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The lipophilicity of the cycloaliphatic systems in these members seems to attenuate the cytotoxical effect and increases the selectivity of those compounds containing the norbornene system. Our results indicate that carbon dioxide was an important greenhouse gas during periods of lower solar luminosity, probably dominating over methane after the atmosphere and hydrosphere became pervasively oxygenated between 2 and 2.2 gigayears ago. Peridural anaesthesia is used to avoid operative, postoperative and chronic pain, especially in surgery, gynecology and urology. rostochiensis indicate that the different subgenomes share fragments with high sequence identity. Asymmetric synthesis of tetrahydroquinolines through supramolecular organocatalysis.

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It has been widely recognized that public policies have important impacts on health. We established the size of the PABP2 mutation in 23 Bukhara Jewish patients belonging to eight unrelated families. Compared to the intact specimens, the use of superelastic cables resulted in stiffer instrumented specimens than the use of multifilament cables for all the loading modes except axial torsion. Experiences with CPP-Based Self Assembling Peptide Systems for Topical Delivery of Botulinum Toxin.

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Retrovirus genomes introduced into mouse zygotes by microinjection of cloned DNA, or into morula stage pre-implantation mouse embryos by infection with Moloney murine leukaemia virus (M-MuLV), became de novo methylated and were blocked in expression. Standard features of a model organism database are provided, including genome browsers, gene list annotation, Blast homology searches and gene information pages. A case of chronic discoid lupus erythematosus with transition into the acute variety of the disease, probably following paratyphus infection.

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Effect of auxin on ascorbic oxidase activity in tobacco pith cells. Urinary concentrations of 12-HETE and 20-HETE of BPH and Pca patients were significantly higher than normal subjects.

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Further, clusters of personality, clusters of parental style of raising and clusters of specific life story factors could be detected. Caregiver refusal of immunizations is associated with topical fluoride refusal. We used a sensitive competitive RT-PCR assay to quantify the amounts of GR and MR mRNA in human brain tissue specimens from patients with focal epilepsies.

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Efficient synthesis of open-cage fullerene derivatives having 16-membered-ring orifices. Can neuropsychic impairment which is clinically observed in the case of HIV-infected patients be objectivized, and what is the relationship to somatic features caused by the disease?

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Foetal uptake of acetate and glucose in the conscious cow during late gestation. A 25 year old, 68 kg, primigravida, was taken up for emergency caesarean section for meconium stained liquor and fetal distress. Parallel Ki-67 immunochemistry of histologic and cytologic samples was performed.

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At baseline (immediately after EICPMS placement) and following each injection, the ICP as indicated by EICPMS was recorded, and 3 ultrasonographic images of the optic nerve sheath of each eye were obtained. Haemolymph PPO activation is normally inhibited in the presence of Plasmodium parasites, but in CLSP2-depleted mosquitoes, the Plasmodium-induced block of melanization is reverted, and these mosquitoes are refractory to the parasite.

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Metabolic data obtained in this study are compared with predictions calculated from an avian flight theory. Short tandem repeat (STR) profiling was carried out to evaluate the contamination of amniotic DNA by maternal genomic DNA. Spectral properties of cytochrome P-450 from lupin nodule bacteroids

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Phase I/Ib study of olaparib and carboplatin in BRCA1 or BRCA2 mutation-associated breast or ovarian cancer with biomarker analyses. Postmortem examination revealed deposition of glycogen in liver cells, a liver cell adenoma, bilateral contracted kidneys with scent glycogen deposition, and pulmonary edema. Infliximab inhibits progression of radiographic damage in patients with active psoriatic arthritis through one year of treatment: Results from the induction and maintenance psoriatic arthritis clinical trial 2. Enlargement of the TIM in GO can be identified on computed tomographic and magnetic resonance imaging scans. Calculations of these errors for some measurement conditions and systems were carried out.

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In search of a prognostic classification of endocrine pituitary tumors. Adenovirus-mediated gene therapy combined with radiation is expected to be a new approach to treat pancreatic cancer. Of the 25 patients treated with modified MMS for DFSP, there were no identifiable recurrences. Serum taken from 10 hypogammaglobulinemic patients immediately prior to infusion of immunoglobulin showed low to negative IgG antibody concentrations, and no IgA or IgM antibody was present.

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We demonstrate that MLC1 is specifically expressed in distal astroglial processes in perivascular, subependymal, and subpial regions. The duration of the light pulse depends linearly on the bubble size, ranging from 200 ns to 1 micros for bubbles with maximum diameters between 0.2 and 1 mm.

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Determination of the catalytic base in family 48 glycosyl hydrolases. Although no evident neuropsychiatric etiological component has been mapped to the 1q32 region so far, this finding may lead to further investigation of a possible linkage between genetic markers of this region and bipolar disorder. Oxaliplatin in combination with fluorouracil/folinic acid is an effective treatment option for patients with metastatic colorectal cancer, both as a first-line therapy and in patients refractory to previous chemotherapy.

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Painkilling drugs in collegiate athletics: knowledge, attitudes, and use of student athletes. Some health plans profile physicians on the basis of their relative costs and use these profiles to assign physicians to cost categories. 2D-gel electrophoresis and mass spectrometry were applied to study the proteome difference in denervated hippocampus in wildtype mice and mice lacking intermediate filament proteins glial fibrillary acidic protein (GFAP) and vimentin (GFAP-/-Vim-/-) that show attenuated reactive gliosis and enhanced posttraumatic regeneration.

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To establish a dynamics model for extracting the lipophilic components in Panax notoginseng with supercritical carbon dioxide (CO2). These results were duplicated in LHRH neurons maintained in vitro in nasal explants. Lava lamp, a novel peripheral golgi protein, is required for Drosophila melanogaster cellularization. A new genus and two new species of Anteroporidae (Cestoda: Lecanicephalidea) from the darkspotted numbfish, Narcine maculata (Torpediniformes: Narcinidae), off Malaysian Borneo.

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This study examined the regional differences in baseline characteristics, treatment, and outcome in patients presenting with ST elevation myocardial infarction (STEMI) who were entered into the Magnesium in Coronaries (MAGIC) trial. The ability of the resistant coliforms to transfer their resistance in vitro to antibiotic-sensitive recipients was examined. Bridge hosts, a missing link for disease ecology in multi-host systems.

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We concluded that this system enables the operator to determine the kinetics and activities of pulmonary enzymes independently of the effects of pressure and flow in a perfusion system that is stable for at least 3 h under physiologic conditions. Cardiac magnetic resonance (CMR) confirmed the site of the fistula and also presence of a significant arteriovenous (AV) shunt. Infection of MDA-MB-231 cells within the lentivirus resulted in approximately a 1 000-fold increase in the expression of VEGI. This uptake was not affected by non-radiolabelled octreotide pretreatment. Without contradicting the wisdom of ligating major veins in the setup of multi-trauma or an unstable patient, our experience indicates that a routine repair of venous trauma can be safely and effectively performed in young patients.

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This system has enabled study of the biological characteristics of RV-C strains, including quantitative research. The gross and histologic appearance of the tumor is described and the literature is reviewed.

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Human liver alanine aminopeptidase is inhibited by L-amino acids having hydrophobic side chains such as Phe, Tyr, Trp, Met, and Leu. Recruitment of osteoclast precursors by stromal cell derived factor-1 (SDF-1) in giant cell tumor of bone. Special care should be taken of purulent pericaditis in differential diagnosis of cardiac tamponade.

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Faecal bacteriotherapy is a safe and simple method capable of curing chronically relapsing forms of pseudomembranous colitis. We calculate the rate of biomarker excretion in normal animals for both collection periods and the bias and correlation in urinary biomarker concentration between collection periods in dosed and control animals, and we estimate the level of agreement in biomarker concentration between both collection periods. However, the odds ratios for prevalent HF according to the increment in the plasma and bone marrow S1P level were not statistically significant. To establish an animal model capable of accommodating (1) direct study of its vertebral arteries and (2) creation of controlled interventions simulating arterial injury.

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We used this approach to map a second marker linked to a gene governing low linolenic acid concentration in a B. While fatty acid acylation does not directly modulate peptide conformation, it promotes self-association of the acylated peptide and association with micelles. Here, the frequencies of several behavioural characteristics related to probing and feeding that are exhibited by non-viruliferous (NV) and TYLCV-viruliferous (V) adult B.

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The aim of this study is to establish an HPLC method for simultaneous determinations of mifepristone and its metabolites, mono-demethylated mifepristone, di-demethylated mifepristone and C-hydroxylated mifepristone in plasma and to evaluate the pharmacokinetic characteristics of mifepristone tablet. Twenty larvae of early fourth-instar stage were used in the larvicidal assay and five replicates were maintained for each concentration. They debated how to ensure that consent was fully informed, and when, and how, to randomize.

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Distribution of absorbed doses in the organs of patients during roetgenodiagnosis The present study was designed to examine the participation of gamma-aminobutyric acid (GABA) receptor mechanisms in the medial preoptic nucleus (MPO) in the drinking response caused by angiotensin II (ANG II) activation of the subfornical organ (SFO) in the awake rat. Endogenous benzodiazepine ligands were extracted from rat brain and human CSF by acid treatment and purification by HPLC.

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In a strain of Salmonella typhi isolated from a patient with post-operative typhoid fever, a 217-Kb conjugative plasmid has been detected which codes for lactose fermentation and drug resistance to sulphonamides (SA), chloramphenicol (CP), ampicillin (AP), kanamycin (KM) and trimethoprim (TP). Deletion of alternative pathways for reductant recycling in Thermococcus kodakarensis increases hydrogen production.

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A case of acute pulmonary edema without cardiac failure, infectious or toxic cause, revealing a Multiple Sclerosis (M.S.), one case of bradycardia during a bout in a known M.S. Metabolic syndrome as a predictor of cardiovascular risk in children and adolescents. A major phosphoprotein of cells infected with pseudorabies virus is phosphorylated by cellular casein kinase II.

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The comprehension of the mechanisms governing this particular sub-cellular localization could allow the design of better candidates for PCI. Another set of studies have revealed preferences for traits indicating complementary genes, focussing on discrimination of dissimilarity at genes in the major histocompatibility complex (MHC). Neonatal consequences of benzodiazepines used during the last month of pregnancy Hemorrhage and hemostasis in specific organs: trachea, bronchi and esophagus Subcutaneous implantable cardioverter-defibrillators (S-ICDs) may prevent some of these complications.

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