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Endoxan (Cyclophosphamide)

Endoxan is a drug that is used primarily for treating several types of cancer. In order to work, Endoxan first is converted by the liver into two chemicals, acrolein and phosphoramide. Acrolein and phosphoramide are the active compounds, and they slow the growth of cancer cells by interfering with the actions of deoxyribonucleic acid (DNA) within the cancerous cells. Unfortunately, normal cells also are affected, and this results in serious side effects. In addition to slowing the growth of cancerous cells, Endoxan also suppresses the immune system and is referred to as immunosuppressive. The FDA approved Endoxan in November 1959.

Other names for this medication:
Cyclophosphamide, Cytoxan, Ciclofosfamida, Cryofaxol, Cycloblastin, Cycloxan, Cycram, Endoxan, Endoxana, Genoxal, Neosar, Procytox, Sendoxan,

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Johann David Schoepf, Surgeon of the Anspach-Bayreuth Troops in America, 1777-1784. Characteristics of the diagnoses and procedures such as associated providers, dates of service, inpatient/outpatient status, and other visit-related characteristics are also fed from the administrative systems. Maternal short stature, low pre-pregnancy BMI, and low rate of gestational weight gain may lead to shortened gestation by increasing the risk of idiopathic preterm labor. p38 inhibition tended to reduce cytokine production more substantially. The majority of SAR was stimulated by HFO, however, the SAR discharge patterns during HFO were less homogeneous than during static lung inflations.

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The measurement of Rivotril in whole blood by gas liquid chromatography. After correcting for trust size and budget, the South London and Maudsley NHS Foundation Trust was the most productive. The disturbances manifested themselves mainly as a decrease in the number of primary and secondary granules in different developing forms of the neutrophil series. It follows that open reduction and fixation is employed when closed reduction fails.

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: Secondary data analysis was performed on an administrative dataset of 29,566 adult Texans who entered publicly funded substance abuse treatment between 2000 and 2005. Relevant databases were searched for prospective randomised controlled trials (RCTs) or quasi RCTs that compared the effectiveness of electrocardiogram-guided catheter tip positioning with placement using surface-anatomy-guided insertion plus chest X-ray confirmation. Drug-coated balloons--the importance of packing and dosing antiproliferative drugs.

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CT imaging during embolization procedures demonstrated a dose-dependent relationship in the number and size of visualized embolized arteries. Improved chemosensitivity in cervical cancer to cisplatin: synergistic activity of mahanine through STAT3 inhibition.

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EFFECT OF ETHANOL OF THE SYNTHESIS OF LIVER TRIGLYCERIDES AND PHOSPHOLIPIDS FROM CIRCULATING PALMITIC ACID-1-C14. Relation of the plasma level of atrial natriuretic peptide and hemodynamic parameters in patients with chronic obstructive pulmonary disease The techniques to manage humeral bone loss are evolving and further biomechanical and clinical studies are required to define the indications and treatment algorithms. Advances in the management of iliac artery occlusive disease: a short review.

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In response to severe damage, p53 phosphorylation at Ser46 is promoted by the accumulation of HIPK2 due to downregulation of nuclear Mdm2 in the later phase of the response. An extract from Eisenia bicyclis, previously shown to possess anti-inflammatory activity, was found to stabilize lysosomal membranes in vitro as determined by measurement of inhibition of the marker enzyme beta-glucuronidase. Measurements of the MHD dynamo in the quasi-single-helicity reversed-field pinch. Association between 5-hydroxytryptamine 2A receptor gene polymorphism and postoperative analgesic requirements after major abdominal surgery.

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The principal aim of this longitudinal study was to investigate the maternal speech directed at very preterm children by examining its changes across time and the stability of maternal individual styles. Conventional treatment and its effect on survival of malignant pleural mesothelioma in Western Australia. Age-specific partitioned reference intervals for alkaline phosphatase, creatinine, and total bilirubin were established for both males and females after being partitioned by sex.

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Increase of portal venous vascular resistance is counteracted by decrease of hepatic arterial vascular resistance (hepatic arterial buffer response). HtrA2 coimmunoprecipitates exclusively with immature APP from cell lysates as well as mouse brain extracts and degrades APP in vitro.

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These articles are analysed according to the groups of authors and topics. Wild-type MTEC exposed to TGF-beta1 demonstrated a prominent induction of mesenchymal mediators and a loss of epithelial markers, in conjunction with a loss of trans-epithelial resistance (TER). On the other hand, spontaneous melanomas of human patients responded poorly to most PDT regimens tested so far.

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Anatomical characteristics of the flexor digitorum accessorius longus muscle and their relevance to tarsal tunnel syndrome a systematic review. Cdt is crucial for this induction and may therefore be involved in the pathological bone resorption during the process of localized aggressive periodontitis. A single mutation in region V of CMV pol can, therefore, confer multiple drug resistance in a clinical isolate.

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We tested the hypothesis that there are no significant differences in the success rates when this condition is treated with triamcinolone injection with or without supplemental oral nimesulide. We found that the biologically active rhVEGF165 was able to improve clonogenic survival of HUVEC-C after 2 and 5 Gy. This is however the first report of such premotor potentials before posed smiles. Consistent diurnal variations in these parameters were observed under standard conditions.

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During a six-month period, 40 consecutive fiberoptic bronchoscopic procedures including bronchoalveolar lavage, bronchial brushing and forceps biopsy were performed in local anaesthesia on 34 HIV-infected males presenting symptoms compatible with Pneumocystis carinii pneumonia. Sucralfate enemas improve the inflammatory process and increase the tissue content of neutral and acid mucins in colon without fecal stream. He had no ocular history apart from myopia, which was corrected with the use of hard contact lenses. Interaction of a folded chromosome-associated protein with single-stranded DNA-binding protein of Escherichia coli, identified by affinity chromatography.

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The aim of this study was to assess whether MBL is associated with diabetic nephropathy in type 1 diabetes, and whether there is an association between MBL and low-grade inflammatory markers or insulin resistance. To examine the three ACE poly-morphic variants in intron 16 for a possible role in modulating DN in T1DM patients from Kutch region, Gujarat. Relationship between calcium stimulation of cyclic GMP and lipid peroxidation in the rat kidney: evidence for involvement of calmodulin and separate pathways of peroxidation in cortex versus inner medulla. Obese subjects consumed their meals and chewed mouthful in significantly less time than did nonobese subjects.

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These changes could be used as an indicator for working state of the reactor. The INO4 gene product is believed to be a positive regulatory factor in a complex cascade of positive and negative factors that coordinates the synthesis of phospholipids in the yeast Saccharomyces cerevisiae. Bisphosphonates induce apoptosis in CLL cells independently of MDR phenotype.

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Shift Work and Prostate Cancer Incidence in Industrial Workers: A Historical Cohort Study in a German Chemical Company. We modified family-focused treatment for adolescents with BD (FFT-A) in order to explicitly target comorbid SUD (FFT-SUD). Two antibodies with known binding epitopes to IL-13 that block binding to either IL-13Ralpha1 or IL-4R inhibited the TR-FRET signal formed by the ternary complex. For those situations and because of the present scarcity of donor organs, SLT must be utilized for selected non-infectious diseases for which it is safe and effective. Staphylococcus aureus is a major pathogen responsible for both nosocomial and community-acquired infections.

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Levoatriocardinal Vein and Mimics: Spectrum of Imaging Findings. Some black stripes disappeared and interstripe areas were emphasized with a yellow color within one year on a white background. If necessary, certain exercises (inspiration/expiration, Valsalva manoeuvre, squats) can be performed to facilitate the aetiological classification of a heart murmur. Effectiveness of complementary and self-help treatments for anxiety in children and adolescents.

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These results provide direct clinical support for the hypothesis that GA induces an inhibition of the activity of 11 beta-dehydrogenase, resulting in a blockade in the conversion of cortisol to cortisone. We present patient examples showing that use of MyoD-transduced fibroblasts as a source of muscle-specific mRNA overcomes these potential difficulties in sequencing large muscle-related genes. Adeno-associated virus type 2 (AAV) is a non-pathogenic DNA virus which has been utilized as a eukaryotic gene transfer vector in vitro and in vivo.

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Coral reef ecosystems are based on coral-zooxanthellae symbiosis. Reduced Coxsackie antibody titres in type 1 (insulin-dependent) diabetic patients presenting during an outbreak of Coxsackie B3 and B4 infection. Effects of various protein-modifying agents and the aminonucleoside of puromycin on dithioerythritol-reducible disulfide in glomerular basement membrane. Lung cancer is the leading cause of death from cancer worldwide with limited available treatment options in absence of specific molecular alteration.

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Some studies suggest that temporal summation, allodynia, and secondary hyperalgesia may be more pronounced in women than in men. Lymphocyte populations in joint tissues from dogs with inflammatory stifle arthritis and associated degenerative cranial cruciate ligament rupture. This review describes recent insights into the mechanisms governing microRNA transcription and processing in cobicistat versus ritonavir medication vertebrates and their implications for understanding the regulation of microRNA biogenesis. The effect of non-ionic detergent tween 80 on colcemid-resistant transformed mouse cells in vitro.

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Effect of sucrose monolaurate on acid production, levels of glycolytic intermediates, and enzyme activities of Streptococcus mutans NCTC 10449. The age of hairdressers, their years of working and the long hours they spent working in a standing position may be significant factors that contribute to the high prevalence of the WMSDs among them. The choleretic effects in dogs of medoclav 625 mg perc the synthetic C-terminal octapeptide of cholecystokinin and of two peptide mixtures, G1 and G2, derived from upper hog intestine.

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The Gly482Ser polymorphism in the peroxisome proliferator-activated receptor-gamma coactivator-1 gene is associated with hypertension in type 2 diabetic men. Development and validation of a predictive screening tool for uninterpretable coronary CT angiography results. This study simulates the potential impact of male circumcision and clarinex d 24 hour ingredients in mayonnaise female microbicide interventions, singularly and in combination, in rural Uganda. Acute hemolysis during cyclosporine therapy successfully treated with vitamin E. No increase of arginase activity was observed in sera of patients with angina pectoris, coronary insufficiency or cardiac failure.