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The male patient died 4 days after the onset and the female finally became vegetative. A less pronounced selectivity of urotensin I for alpha-1 adrenoceptor-mediated contractions could be demonstrated in isolated strips of the superior mesenteric artery of the rat.(ABSTRACT TRUNCATED AT 250 WORDS) Abnormal phonation among ICU and intermediate care unit patients is associated with dysphagia and aspiration. Procedure time, numbers of needle insertion attempts and needle passes, visual analogue scale for pain and Oswestry disability index at 1 and 3 months posttreatment. Susceptibility of PTEN-positive metastatic tumors to small interfering RNA targeting the mammalian target of rapamycin.

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Isolation and analysis of somatic hybrids derived from two human diploid cells. Significantly, p53 promoter-driven CAT expression was visualized in the Purkinje cells of the cerebellum and in the cornea as well as in the retina of the eye. A protein, which was immunoreactive to antibody against cytochrome c oxidase, was found in the mitochondrial membrane fraction of sweet potato root tissue. Infector mice transmit influenza virus infection most readily during the period 24 to 48 hours after initiation of their infection.

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Recent findings in SMZL contributed to a better characterization, including the few cases associated with hepatitis C, the recurrence of 7q deletion and the possibility of CD5 expression. The contrasting effects of emotional tension and physical exercise on the excretion of 17-ketogenic steroids and 17-ketosteroids. Here, we investigated a possible role of EZH2 for the growth control of colon cancer cells. A study of insertion/delation polymorphism of the angiotensin-converting enzyme gene in pilots

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Results of experimental studies on dihydrostreptomycin paraaminosalicylate Changes in the relative strengths of the different trunk muscle groups is affected by spinal pathology, and this is discussed. Body composition, food intake, and brown fat thermogenesis in pregnant Djungarian hamsters. The overexpression of the lipase gene (lip9) was achieved when T7 promoter was used and the signal peptide of the lipase was deleted.

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Prevention of parodontosis due to the action of noise and vibration Reciprocal actions in the ternary system ethyl alcohol--internal standard--blood proteins The Model of Uptake with Instantaneous Adsorption and Efflux, MUIAE, describing and predicting the overall Cd uptake by the metal-resistant bacterium Cupriavidus metallidurans CH34, is presented.

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Radiographic assessment of the patella after total knee arthroplasty is typically performed with use of static, unloaded views that may not reproduce the in vivo patellofemoral kinematics. Association of xeroderma pigmentosum group D (Asp312Asn, Lys751Gln) and cytidine deaminase (Lys27Gln, Ala70Thr) polymorphisms with outcome in Chinese non-small cell lung cancer patients treated with cisplatin-gemcitabine. Results of the scientific research work of departments of drug technology in institutions of higher learning of the Ukrainian SSR Cytotoxic and anti-inflammatory tirucallane triterpenoids from Dysoxylum binectariferum. Lanthanide chelates as new fluorochrome labels for cytochemistry.

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We retrospectively reviewed the records of 48 patients who had undergone salvage RT for biochemical relapse after RP. The results show that these genes are circulating among Enterobacteriaceae strains in Hungary and indicate that strict infection control measures are warranted in order to prevent their spread. Whereas there are already extensive studies on the direct effects of hyperthermia on DNA, RNA, and protein synthesis, energy metabolism, and the membrane properties of tumor cells, the indirect effects have only been investigated more closely in recent years. The stimulated salivary clearance of Tc-99m pertechnetate (SSCP) introduced in 1985 by Blue and Jackson is revisited here in patients with known or possible salivary disorders and correlated with most commonly cited and up-to-date quantitative indices obtained from standard dynamic salivary scintigraphy. In these amoeboid cells the molecular events leading to directed migration can be conceptually divided into four interacting networks: receptor/G protein, signal transduction, cytoskeleton, and polarity.

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The correct diagnosis could only be confirmed in a second cerebral biopsy, allowing for proper treatment with radiation therapy. We assessed the prognostic value of MMP-1 mRNA expression in tumor tissue specimens from 85 breast carcinoma patients with a median follow-up time of 38 months (range, 2-48 months). Sulbactam, ampicillin and cefazolin at 32 micrograms/ml did not inhibit MRSA or MRSE.

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These results suggest enhanced membrane phospholipid turnover in the pineal gland of SHR. The intermediate bound to the enzyme rapidly, with a second order rate constant of 5 x 10(7) M-1 s-1. Fast in vivo quantification of T1 and T2 MRI relaxation times in the myocardium based on inversion recovery SSFP with in vitro validation post Gd-based contrast administration.

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The incidence and correlation of allergy and chronic maxillary sinusitis. Local anesthetic action and effect on the autonomic nervous system. Antibiotic lock technique (ALT) may be an adjunct therapy in treating catheter-related infections.

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Plasma HIV-1 load and nosocomial transmission in Romanian children. Effects of switching from anastrozole to letrozole, due to reimbursement policy, on the outcome of breast cancer therapy.

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A dramatic increase in endothelial proliferation was followed by expansion of the local SVZ vascular tree 7 days after the injury. This heterogeneity is probably secondary to the fact that a large proportion seems to occur from a transformation of an unknown indolent lymphoma. Tap water has been shown to markedly potentiate the polivirucidal effectiveness of FC at pH 9.0. The isotopic analysis of boron from material that carries only trace amounts of boron requires low boron blank levels.

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Reactions of laser-ablated copper atoms with carbon monoxide and dinitrogen in excess argon have been investigated by matrix-isolation infrared spectroscopy. Methods for recognizing the different developmental parameters in the size distribution of muscle fibers are described and three empirical examples interpreted in terms of the model.

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The main tool used in this study was a questionnaire developed from a focus group interview of ten psychiatrists about their attitudes toward OCD patients. Semliki Forest virus induced, immune mediated demyelination: the effect of irradiation. We showed the nuclear texture has specific changes at different mitotic stages and this can be used for more precise staging of mitosis. Zebrafish evx1 is dynamically expressed during embryogenesis in subsets of interneurones, posterior gut and urogenital system. A systematic review of the literature was carried out performing an unrestricted search in MEDLINE, EMBASE and Cochrane Library up to 28th February 2014.

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The patients were placed randomly on either magnesium supplementation (intravenous plus oral) or placebo. On revision surgery, tension forces to the right were therefore neutralised by additional transmuscular sutures on the right side. Tuberculous spondylitis in spondylolytic-spondylolisthetic vertebra

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To investigate the level of control of alpha-fodrin expression, we isolated two cDNA clones for oocyte alpha-fodrin. Blood pressure levels remained unchanged, despite up to a 20-fold increase in plasma catecholamines. The Ce (IV)-doped TiO(2) nanoparticles displayed their superiority. Surgical outcomes of LTG were investigated and compared with those of patients who underwent LDG. The stress response, characterized by a transient downregulation of most cellular products and by the upregulation of the heat-shock proteins (HSPs), has been shown to provide protection to cells and experimental animals if triggered prior to an otherwise lethal injury.

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These results suggest that the microsomal enzyme is a precursor of the mitochondrial enzyme, that the levels of A-form and B-form MAO are regulated genetically, and that the two forms of MAO may be synthesized separately. Fos was detected in many magno- and parvocellular NADPH-D positive neurons in response to haemorrhage or drug-evoked hypotension using i.v. Symptom trajectories and psychosis onset in a clinical high-risk cohort: the relevance of subthreshold thought disorder.

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Its appearance and distribution were unlike those of any known cavernous branch, originating at the level where the trigeminal artery is usually found but having no communication with the basilar artery. However, determination of the cup area based on computation algorithm is very difficult, thus we propose a method to measure the cup-to-disc ratio using a vertical profile on the optic disc.

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Detecting an imaging signal from a small number of cells is vital when a disease needs to be diagnosed in an early stage of development. Heterologous expression of active thymidylate synthase-dihydrofolate reductase from Plasmodium falciparum. ESII seemed to be accurate in predicting the risk of SAVR patients.

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Characteristics of spitzoid melanoma and clues for differential diagnosis with spitz nevus. Genetic rat models for childhood absence epilepsy have become instrumental in developing theories on the origin of absence epilepsy, the evaluation of new and experimental treatments, as well as in developing new methods for automatic seizure detection, prediction, and/or interference of seizures. We examined the effect of gender-associated differences in pharmacokinetics on the anti-arrhythmic effects of flecainide in Japanese patients with supraventricular tachyarrhythmia and in healthy subjects. This enzyme catalyzes the two-electron oxidation of ubiquinol-8 which is located in the cytoplasmic membrane, and the four-electron reduction of molecular oxygen to water.

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The affinity toward aminoundecanoic acid-2,4-D derivatives, for instance, was improved about 100-fold compared to 2,4-D alone and yielded detection limits as low as 100 amoles of analyte. Target cells from 10 of 11 HL-A7-positive donors were damaged in vitro by this antiserum together with lymphocytes from normal donors. Mealtime support and standards of dignity patchy, but improving. Nattokinase (Subtilisin NAT, NK) is a bacterial serine protease with high fibrinolytic activity.

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SIMQUADNMR: a program for simulation and interpretation of multiple quantum-filtered NMR spectra of quadrupolar nuclei. The imaginary component also follows a simple relationship but only up to a certain coverage, above which it increases rapidly. Results of fast neutron therapy of adenoidcystic carcinomas of the head and neck at the neutron facility Hamburg-Eppendorf.

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Insomnia is a frequent problem in people who suffer from mental illnesses. A photoconvertible fluorescent reporter to track chaperone-mediated autophagy. Item response scales and composite scoring of all candidate PROMs were suboptimal to our specific purpose. Subjects were 105,946 White, Black, and Hispanic residents aged 15 years and older, dying in the US between 2003 and 2005, whose manner of death was recorded as suicide or injury of undetermined intent. In a polymerase chain reaction study of paraffin-embedded tissues, analyses for the rearrangement of immunoglobulin heavy chain and T-cell receptor-gamma genes were negative.

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Site-selective Cu(I)-catalyzed reactions have been developed on microelectrode arrays. A significant minority of lifetime marijuana users will eventually receive a diagnosis of abuse or dependence.

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The operative techniques draw considerable benefits from intraoperative radiography and, when necessary, the clamping of the renal pedicle under pharmacological protection. The volume of messages and the time spent answering messages for the e-mail group physicians was not increased. Studies of the branching patterns of individual ganglion cell axons suggest that during the period when inputs from the two eyes are intermixed, axons from one eye send side branches into territory later occupied exclusively by axons from the other eye. The strongest predictors of levels of genetic variation in susceptibility were disease characteristics negatively associated with immune effectiveness.

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In this review we will briefly discuss the current pipeline of drugs for schizophrenia, outlining many of the strategies and targets currently under investigation for the development of new schizophrenia drugs. Efficiently hiding sensitive itemsets with transaction deletion based on genetic algorithms. Microtubule depolymerization inhibits transport of cathepsin D from the Golgi apparatus to lysosomes. Evidence for a super-reduced cobamide as the major corrinoid fraction in vivo and a histidine residue as a cobalt ligand of the p-cresolyl cobamide in the acetogenic bacterium Sporomusa ovata.

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A conservative treatment with analgesics, dexamethasone and hydantoin was indicated. Histopathological examination revealed the retinopathy in the eyes of rats treated with ZnO NPs. Studies have found a relationship between decreased immunity and increased incidence of cancer. Multi-locus sequence typing of Ehrlichia ruminantium strains from geographically diverse origins and collected in Amblyomma variegatum from Uganda. A biotin interference assay highlights two different asymmetric interaction profiles for lambda integrase arm-type binding sites in integrative versus excisive recombination.

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In addition, it provides information on the physical and functional interactions among proteins as well as other genetic elements. Therapeutic activity of cefotiam was about 9 approximately 15 times as potent as that of cefazolin in experimental pneumonia caused by K. Exceeding 2 hrs of daily total screen-time was negatively associated with MVPA for both boys and girls, and with VPA for girls.

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By characterizing these mutations we can aim to define and target populations of pathogenic autoantibodies that cause autoimmune rheumatic diseases. No significant effects on blood lipids were observed in the main study to a soy supplementation in hypercholesterolaemic subjects after 24 weeks.

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Clones HMS-41/I, -78/2, and -98/2 were developed from cell lines HeLa AV3, MBA 9812 (bronchogenic carcinoma), and SW 267 (pheochromocytoma), respectively. SrfB, a member of the Serum Response Factor family of transcription factors, regulates starvation response and early development in Dictyostelium. Semaphorin 7a promotes spreading and dendricity in human melanocytes through beta1-integrins.

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Influence of xerostomia on oral health-related quality of life in the elderly: a 5-year longitudinal study. Studies varied in onset of the training, the training protocol and the outcomes measured. The thrombogenicity of prothrombin complex concentrates (PCCs) has been known as a risk factor since their first clinical use about 30 years ago. In the particular case of bony ankle impingement associated with poorly tolerated range of motion restriction, both pain and joint mobility can be improved by simple arthroscopic surgical techniques combining anterior synovectomy, extensive anterior capsuloligamentous release, large-scale osteophyte resection and malleolar groove release. Significant sex differences in the correlation of electrocardiographic exercise testing and coronary arteriograms.

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The derived control chart limits were in agreement with AAPM TG114 guidelines on action levels. Preventive measures for avoiding conditions that compromise the safety of aviation operations at night are discussed.

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A simple and efficient process to cyclize triols containing a 1,2-diol functionality with a pendant hydroxyl group is presented. Speech and aesthetic concerns seem to have been important factors affecting the health-related quality of life for children with oral clefts. Other experiments used microinjections that were below threshold for involuntary vocalization. Uncomplicating the Macrovascular Complications of Diabetes: The 2014 Edwin Bierman Award Lecture.

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We found that the increase of plasma corticosterone (CS) concentration is lower in sialoadenectomized than that in sham-operated mice. Macrophages may play a pivotal role in cutaneous wound repair by producing bFGF not only during the inflammatory or proliferative stages but also during the remodelling stage. Left ventricular (LV) dysfunction after trastuzumab treatment in erb-2 breast cancer cases has been fully investigated. Its role in functional recovery is time-dependent while its major adverse effect, intracranial haemorrhage, is dose-dependent.

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Multimodal therapeutic concepts in cancer therapy more and more often allow a curative approach even in advanced stages of the disease. Sustained responders, at least HLA-A2 patients, elicited a more potent CTL immunity against YMDD and its mutants. THE EFFECTS OF INANITION ON THE HUMORAL RESPONSE TO EXPERIMENTAL INFLAMMATION.

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Immunohistochemical staining showed that the tumor cells were positive for cytokeratin, CD56, synaptophysin and chromogranin A, and negative for inhibin, placental alkaline phosphatase and alpha-fetoprotein. CHARACTERIZATION OF DNA ISOLATED BY DIFFERENT METHODS AND ITS RELATION TO VIRUS STRUCTURE. The N-oxide metabolite contributes to bladder selectivity resulting from oral propiverine: muscarinic receptor binding and pharmacokinetics. In 13 of the 14 cases the neuralgia completely disappeared postoperatively.

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The patterns found represent a kind of electronic footprints that makes it possible to discern between aromatic and antiaromatic systems. Forskolin (10(-7) M) increased the sensitivity and amplitude of the response. Plasma cell leukemia induced to complete remission with negative minimal residual disease by qualitative PCR analysis after hyper-CVAD and high-dose melphalan followed by autologous peripheral blood stem cell transplantation

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Prevention of atrial fibrillation by Renin-Angiotensin system inhibition a meta-analysis. There was no influence from factors such as fitness level, age, hypoxia, and blood distribution. The results showed that the mutant lacks an external calcium-dependent NADPH dehydrogenase. How the size of the needle electrode leading-off surface influences the shape of the single muscle fibre action potential in electromyography. The prognostic value of emergency echocardiography (EE) in the management of cardiac arrest patients has previously been studied in an in-hospital setting.