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Karum (Clopidogrel)
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Clopidogrel

Karum is an antiplatelet medicine, or blood thinner. It makes your blood flow through your veins more easily. This means that your blood will be less likely to make a dangerous blood clot. Taking Karum helps prevent blood clots if you have an increased risk of having them. Your risk is higher if you have or have had: a heart attack; unstable angina; a stroke or "mini-stroke" (transient ischaemic attack or TIA); peripheral arterial disease; an operation on your heart or blood vessels, such as a coronary stent insertion. Karum comes as tablets and is only available on prescription.

Other names for this medication:
Clopidogrel, Plavix, Anclog, Anlet, Antiplar, Artevil, Clavix, Clopicard, Clopilet, Clopivas, Deplatt, Diloxol, Duoplavin, Expansia, Farcet, Globel, Grepid, Iscover, Karum, Klopidogrel, Nabratin, Narutis, Nefazan, Noklot, Pidocar, Pidogrel, Pladex, Plagerine, Planor, Tisten, Troken, Trombex, Vaclo, Zyllt,

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Minimally destructive management of amelogenesis imperfecta and hypodontia with bleaching and bonding. The dust acoustic wave (DAW) spectrum is reexamined to account for the dust charge fluctuation dynamics in a thermal dusty plasma whose constituents are electrons and positively charged dust particulates. A case of extreme hyperglycaemia in diabetic coma with recovery. This study also revealed lower prevalence for most asthma and allergy, and respiratory symptoms in children attending NV CCCs. Based on comprehensive spectroscopic analyses including IR, ESI-MS, HR-ESI-MS, and 1D and 2D NMR, their structures were elucidated as 18-demethoxyltransconitine A (1) and 8-O-anisoyl-14-hydroxylacoforesticine (2).

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In conclusion, although nanoparticles are not always the right choice for molecular imaging (because smaller or larger molecules might provide more specific information), there are other diagnostic and theranostic applications for which nanoparticles hold substantial clinical potential. Successful infection of the common marmoset (Callithrix jacchus) with human varicella-zoster virus.

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Deleterious mutations can be efficiently induced by expression of a synthetic nuclease that targets a gene of interest. The aim of this study is to analyse the construct, content and criterion validity of the GFI in independent-living old Romanians. The theoretical methods used to predict the phase transition are validated by comparing their prediction to the well-characterized ice VII/VIII proton-ordering transition. Microvessel and mast cell densities were investigated in tumour specimens from 60 patients with colorectal carcinoma.

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Anthropological studies of the extensive dental samples from Neolithic (MR 3) and Chalcolithic (MR 2) levels at Mehrgarh, Baluchistan, and Bronze Age Harappa, Punjab, yielded several interesting examples of unusual dental abrasion. EOPs are involved in the mediation of the elevations in nociceptive threshold, core temperature, exploration and grooming behaviour elicited by stress. Wild-type CD8 lymphocytes were transferred to nude mice followed by heterotopic heart transplantation. Electromyographic activity during sprinting was recorded for the biceps femoris long head, semitendinosus, and semimembranosus muscles of ipsilateral limb.

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In vitro activity of sulbactam/ampicillin against ampicillin-resistant, beta-lactamase-producing bacteria isolated in Italian hospitals. The objective classification of results of the previously described symmetry detector method for gamma encephalography is reported. These are indispensable for qualitative laboratory work as well as for future prospective studies aimed at providing prognostic information for spontaneous pregnancies and successful Assisted Reproductive Techniques (ART) treatment.

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Here we demonstrate how controlled degeneracy of the respective electronic orbitals maximizes this backaction and leads to stronger binding energies and lower symmetry of the bound dimers. Sonidegib exhibited low absorption, was extensively distributed, and was slowly metabolized. The paper describes the structural design, the Nyquist impedance response, the measurement sensitivity and accuracy, and the field testing of the nitrate sensor performed within tree nursery settings under ISO/IEC 17025 certifications.

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We examined associations between a wide range of DSM-IV mental disorders with adult onset of asthma and whether observed associations remain after mental comorbidity adjustments. Clinical observation and study of blood phosphate concentration changes in postoperative patients

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During HM, we analyzed: arrhythmias, QT intervals, the presence of late ventricular potentials (LP), heart rate variability, heart rate turbulence. Melanoma cells were implanted directly into the inguinal lymph nodes in mice, and micro-MRI was performed using a customized 1.5-T clinical MRI system.

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Knowledge and beliefs about urinary incontinence in adulthood and old age. The in situ infiltration of polymorphonuclear leukocytes following the topical application of leukotriene B4 to the clinically uninvolved skin of psoriatic patients and the skin of normal controls has been quantified using elastase as a marker enzyme. The micrococci are black, and have an average diameter about 0.5 micro.

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The inner ear will detect whole-body accelerations generated by changes in flow, or by turbulence, whereas visual and tactile inputs will signal translational movement with respect to an external visual or tactile reference frame. Limited elimination of two viruses by cryotherapy of pelargonium apices related to virus distribution.

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The Rural and Remote Area Placement Program (RRAPP) began in April 2000 to provide a rural community practice training term for junior doctors and to increase the opportunities for junior doctors to experience training outside the hospital setting. The bariatric team and patients should be aware that mental health may play a role in the decision for conversion to gastric bypass. During the discharge of m.e.p.s.p.s produced by BWSV, the increase in the aspartate efflux was very small compared to glutamate. Population-based study of asymptomatic infection with Chlamydia trachomatis among female and male students. Defects in medullated retinal nerve fibres were continous with arcuate nerve fibre bundle defects.

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In addition, rApfA improved the vaccination potential of the penta-antigen mixture of rApxIA, rApxIIA, rApxIIIA, rApxIVA and rTbpB proteins, where the hexa-antigen vaccine containing rApfA conferred a high level of protection on pigs against the disease. The cells prior to transformation are diploid and because they have been in culture only for a few passages prior to transformation with the oncogene it is unlikely that any preexisting mutation affecting radiation response could be present.

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Abnormal 5-HT function could be a result of disturbances at various pre- and postsynaptic levels. Mismatch negativity: no difference between treatment-naive alcoholics and controls. We therefore prevented DNA replication and cytokinesis, which ensue after nuclear transfer, in order to assess their requirement for transcriptional reprogramming of the key pluripotency genes Oct4 (Pou5f1) and Nanog in cloned mouse embryos. Primary tumours in the pancreas and liver metastases could be diagnosed with CT and ultrasound, except for two small insulinomas, which required angiography.

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This nucleosome dissolution required positive superhelical stress as evidenced by the requirement that the extended RNA transcript remain associated with the polymerase during the transcription process. Lubiprostone is approved by the FDA for IBS with constipation, and alosetron in IBS with diarrhea (IBS-D). The current combination therapy consisting of interferon-alpha and ribavirin mainly acts by supporting host cell defence. Differential Modulation of Thresholds for Intracranial Self-Stimulation by mGlu5 Positive and Negative Allosteric Modulators: Implications for Effects on Drug Self-Administration. A disagreement between experimental data and the theoretical results for alpha(4) is attributed to the fact that the isotropic contribution to alpha(4) in the nematic phase is beyond the scope of the theories that are based on the anisotropic orientational distributions.

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Current status and therapeutic strategy for hepatocellular carcinoma Cytomegalovirus infection in the renal allograft recipient has been associated with the initiation of acute rejection. In vitro standardization of two different removal devices in cemented implant prosthesis. Influence of different exchangers on the mobility in chloroform-formamide and correlation of chromatographic data. The colocalization of neurotransmitter proteins in early neuroblasts (60 hr of embryogenesis) supports the recent concept that these substances themselves may influence phenotypic expression and also supports our idea that microenvironmental factors (i.e., ethanol, growth factors) provide signals which affect emerging phenotypes.

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The combination of the necessary diagnostic procedures, as CT scan, angiography, ventriculography, serial biopsy within a single three coordinate reference system offers considerable advantages for brain tumour patients. We strongly recommend fine needle aspiration cytology for the diagnosis of primary carcinoma of liver. ABE also triggered the downregulation of Akt, and combined treatment with LY294002 (an inhibitor of Akt) significantly decreased cell viability. A systematic review of the literature was conducted for different screening strategies in terms of age (60, 65, or 70 years) and risk profiles (all men or specific high-risk groups) of the screened population, and rescreening after 5 or 10 years. In the present studies we used a multisite ceramic-based microelectrode for rapid (800 ms) and low level measures of L-glutamate in vivo.

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Based on the predicted demographic changes with an ageing society an increase of the prevalence and thus also an increase of costs for eye diseases is expected in the future. Interviews were conducted by trained interviewers located at the SST Coordinating Center, via a computer-assisted telephone interview system that randomly assigned the order of instrument administration. A comparative study on three-dimensional digital model of knee joint anterior cruciate ligament between normal adult and corpse based on magnetic resonance imaging reconstruction EGFR activation involves an integrated signaling pathway that includes NADPH oxidase activation of metalloproteinase, and EGFR proligand release that activates EGFR.

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Meningitis, septicemia and endophthalmitis caused by Streptococcus equi subspecies zooepidemicus Processing and characterization of silver films used to fabricate hollow glass waveguides. Early-stage chronic kidney disease, insulin resistance, and osteoporosis as risk factors of sarcopenia in aged population: the fourth Korea National Health and Nutrition Examination Survey (KNHANES IV), 2008-2009.

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Since then, stevia has been approved as a sweetener for the European market. Striae distensae represent a common skin condition, corresponding to a physiological event particularly developed during adolescence, pregnancy and gain in body weight. The incorporation of biologically occurring or chemically synthesized non-canonical amino acids into recombinant proteins and even proteomes via reprogrammed protein translation is in the heart of these efforts.

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Preliminary examples of electro-oculography (EOG) signal analysis during sleep are presented. Neither Gly-Gln nor Gly-Glu influenced the accumulation of cyclic AMP in the cultures.

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The clinical effectiveness of a new flossing device, the Floss Plus easy flosser, in reducing interproximal plaque and interproximal gingival inflammation was compared to the effectiveness of hand-held floss. Despite that, current debate remains narrowly focused on the role of calcium loading from calcium-based phosphate binders (CBPB) in the pathogenesis and progression of CVC. Multistage cluster sampling was employed to recruit 293 medical science students (Male: 95/Female: 198) from 7 faculties in Tehran University of Medical Sciences. Position of the hexapeptide relative to the homeodomain is important. Based on their unique structural and physical properties, functionalized CNT substrates have been used due to the fact that independent variation in molecular as well as electronic properties could be controlled by understanding the wetting of these liquids on carbon nanotubes (CNTs), both pristine as well as ozone treated.

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Effectiveness of a nurse-tailored HIV/AIDS medication adherence intervention: an unresolved issue Certain variants of the hemopoietic system in diphyllobothriasis Moreover, promising results are also being reported against molecular targets, particularly with inhibitors of EGFR. UVER efficiently removes both cyclobutane pyrimidine dimers (CPDs) and pyrimidine (6-4) pyrimidone photoproducts (6-4PPs) from genomic DNA.

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Comparative analysis of different water conditioning technologies, i.e. Glutathione-S-Transferase M1 (GSTM1) is one of the genes involved in detoxification of endogenous and exogenous compounds. The mean values of egg weight, eggshell thickness, Haugh unit, thick albumen height, yolk height, and yolk diameter were calculated.

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This review summarises the state of knowledge concerning the early stages of enteric nervous system development and concentrates on: (i) the embryological origins of the neural crest cells which colonise the gastrointestinal tract, (ii) their spatiotemporal migration within the gut, (iii) the possible pre-specification of neural crest cells as enteric nervous system precursors and (iv) factors influencing their directional migration within the gut. Tapping into water: key considerations for achieving excellence in school drinking water access. Clarifying the nomenclature of intervertebral disc degeneration and displacement has important implications both for investigators and for physicians. The ability of HCV to infect central nervous system cells seems to be significant in the hypothalamus--epiphysis--axis dysfunction.

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MECHANISMS OF ENDOTOXIN TOLERANCE IN RELATION TO CARBOHYDRATE METABOLISM. This observation shows that the apparent Fermi surface nesting alone is not enough to enhance the antiferromagnetic correlation as well as the superconducting transition temperature. Serum Soluble Interleukin-2 Receptor Levels in Patients with Breast Cancer. NT71 and NT72 did not cause any significant in vitro or in vivo toxicity, in contrast to sodium channel blockers. Elderly patients referred to an SNF for prosthetic training have a high probability of using a prosthesis when having an independent ambulation after transtibial amputation, without phantom pain.

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HIPK2 and Wip1 expression is also negatively correlated after cisplatin-based combination chemotherapy in vivo. In this report, we highlight the artefactual mislocalisation errors which may occur with PET/CT imaging, and the need to review and verify these scans. It also inhibited HUVEC proliferation by the induction of cellular apoptosis and cell-cycle arrest at the G0/G1 phase. Antemortem measures of hippocampal volume have been used to distinguish subjects with and without probable Alzheimer disease (AD). Submit complex 3-IV as the nucleotide binding site of Q-beta replicase.

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Exploitation of the differential binding properties of these mAb indicated that mutant (as distinct from WT) TNFRSF1A showed abnormal intracellular retention in the neutrophils of TRAPS patients with the C33Y mutation, with little if any expression of mutant TNFRSF1A on the cell surface or as soluble receptor in plasma. The data generated from these model organisms have made unique contributions to our knowledge of spindle positioning. This is the second described case of endothelial graft failure after DLEK. Impact of variation in endocervical specimen collection and testing techniques on frequency of false-positive and false-negative Chlamydia detection results. subtilis and other Bacillus species, including Bacillus anthracis, bound rabbit IgM through an unconventional, superantigen-like binding site, and in vivo, surface molecules of B.

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When fused to beta-galactosidase, these peptides, like the normal invertase signal sequence, direct the hybrid protein to a perinuclear region, consistent with localization to the endoplasmic reticulum. Thus, we could demonstrate in CHO-K1 cells that 25-OHC activates the apoptotic machinery through induction of the release of cytochrome c from mitochodria into the cytosol and activation of a typical caspase cascade. Finally, we describe a novel activation pathway hitherto unknown for the activation and viral inhibitory characteristic shown by these phosphoramidate derivatives of stavudine. PCR reveals starling gonads express mRNA for gonadotropin inhibitory hormone (GnIH) and its receptor (GnIHR) and melatonin receptors 1B (Mel 1B) and 1C (Mel 1C). The exceptional high thermostability of BLA, although produced by a nonthermophilic organism, is not fortuitous but subject to a selective pressure still at work in natural environments.

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Effects of intravenous administration of hydrochlorothiazide on renal hemodynamics and excretion of electrolytes junior lanzol 15 mg in hypertensive patients Acknowledgement of the way that different groups approach lifestyle behaviours may assist acceptability of interventions. Pathogenic implications of age of onset in juvenile rheumatoid arthritis. Antibacterial effect on Staphylococcus of lipids from human sebum In addition, one of the patients has esophageal achalasia, which has rarely been described in WS.

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