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Urokinase (uPA) is a serine protease, which together with uPAR, tPA, PAI 1 and PAI 2 forms the plasminogen activator system, a component of metastatic cascade contributing to the invasive growth and angiogenesis of malignant tumours. Surgical treatment of lumbosacral pseudarthrosis and spondyloptosis in a patient with neurofibromatosis type 1 and a large lumbar anterior meningocele.

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A 2-stage treatment protocol with implantation of an antibiotic-loaded cement spacer is an efficient option in the treatment of fungal periprosthetic infections. Citrogenase activity of the cartilage in young rabbits of various ages Based on these findings, an alternative explanation is given for the reduced optical gaps in this size regime. The NZB/NZW hybrid mouse is an animal model of human systemic lupus erythematosus (SLE). Generation of two- and three-dimensional lacrimal gland constructs.

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Mononuclear cells cultured in presence of LEAP-2 or LL-37 demonstrated reduced levels of IL-10. The association of anti-nuclear antigen (ANA) and anti-cardiolipin (CL) antibodies is often observed during systemic lupus erythematosus (SLE) or the primary anti-phospholipid syndrome, thereby raising the possibility of a relationship between these two autoantibody populations.

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Factor so bound can still be recognized by a specific antibody to release factor-2. If each flash in the flicker is localized individually in the same way as a single flash, the apparent position and length of the flicker should be predicted from the time course of mislocalization of a perisaccadic flash. Prolactin and prolactin receptor interactions in normal and neoplastic tissue.

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NPM1 and CEBPA mutations are associated with clinical outcome in AML patients. 11 ATTEMPTS AT RENAL HOMOTRANSPLANTS IN MAN AFTER IRRADIATION OF THE RECEIVER At an early age, the bone marrow is still active at other sites, for example the orbital wall, and thus infarction can also occur there.

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In response to different stimuli, apoptosis may be initiated extrinsically by the death receptor pathway or intrinsically by the mitochondrial pathway. The results of EVEREST will determine whether these effects translate into improved clinical outcomes. Proteomic analysis highlighted twelve modulated proteins related to central metabolism: MetE and MccB (cysteine metabolism), OdhA, AspB, IolD, AnsB, PdhB and YtsJ (Krebs cycle) and XylA, YqjI, Drm and Tal (pentose phosphate pathway). The standard is based on an average adult Drosophila VNC neuropil as labeled in 24 whole-mount preparations with the commercially available antibody (nc82) recognizing the Drosophila Bruchpilot protein (Brp). In the present study, we show that, whereas PECAM-1 is known to control positively the trans-endothelial migration of leukocytes via homophilic interactions between leukocytes and endothelial cells, PECAM-1 engagement on brain endothelial surface unexpectedly counteracts the ICAM-1-induced tyrosine phosphorylation of cortactin and rearrangements of the actin cytoskeleton.

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Titanium and titanium alloy have been widely used in several bioimplant applications, but when implanted into the human body, these still contain some disadvantages, such as poor osteointegration (forming a fibrous capsule), wear debris and metal ion release, which often lead to clinical failure. AYA patients are at a higher risk for toxicities from regimens that may be tolerated by younger patients.

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Depression research has been trying to improve the response rates to treatments by identifying a valid set of differential predictor variables. In each analysis, sex was included as an additional grouping factor. Transgenic alfalfa plants expressing AtNDPK2 exhibit increased growth and tolerance to abiotic stresses. Device closure obviates the need for general anesthesia and a surgical incision and eliminates postoperative pain, long convalescence, and lifelong scarring. Differentiated iPS cells offer an alternative cell source for constructing TEVG.

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Application of capillary electrophoresis in analysis of disease specific proteins It could be well integrated into a multi-modal treatment scheme. Serum YKL-40: a new potential marker of prognosis and location of metastases of patients with recurrent breast cancer. Participating groups submitted 1 year of data for continuously enrolled patients. The enzymatic synthesis of citrulline from ammonia, bicarbonate, adenosine triphosphate, and L-ornithine takes place in the soluble fraction of gut tissue of the earthworm.

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Alterations of the TP53 gene are frequently associated with resistance to chemotherapy, but their significance in relapsed childhood ALL has remained controversial because of small studies. The data sets were compared to determine whether open-sources could recreate the population of homicides and variable responses collected in official data.

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Prospective cohort study of patients with AIDS, conducted from 1998 through 2003. The mechanotransduction mechanism of how osteoblasts respond to mechanical stimulation However, the order of content for latter five elements was not the same in different matrixes.

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A review of current diagnostic and therapeutic aspects and report of a case The highest mean perfusion pressure in fetal circuit was observed in placentas perfused with Captopril in the dose of 100 ng/ml, whereas Captopril in the dose of 1000 ng/ml significantly decreased perfusion pressure after 180 minutes of the experiment.

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Two independent clones of hybridomas were isolated by fusing murine myeloma cells, NS-1, with spleen cells of a rat which was immunized with murine 3T3 fibroblast. Hereditary and acquired defects in the pyrimidine nucleotidase of human erythrocytes. Fetal serum ferritin and cobalamin in red blood cell isoimmunisation.

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Postnatal events contribute to features of the metabolic syndrome in adulthood. The CAP marker residing in the 1-FEH w3 promoter region may facilitate wheat breeding by selecting lines with high stem fructan remobilization capacity under terminal drought. The genomic DNA from 11 of 44 sarcomas contained somatic alterations in the lengths of one or more di-, tri-, tetra-, or pentanucleotide microsatellite sequence markers, and 6 of these cases had alterations in two or more markers. Nontumoral, benign and malignant transformation appeared at different stages. The case demonstrates the importance of prompt diagnosis and adequate therapy that helped in preventing an assumingly life-long complication or even death.

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