Norsic works through two mechanisms. The first is by acting on dopamine receptors. Dopamine is a signaling molecule in the brain that plays an important role in motor control and thinking abilities. In Huntington’s disease patients, dopamine levels are imbalanced. In the early and intermediate stages of the disease, dopamine’s activity is too high, which is thought to cause chorea. Norsic binds to dopamine receptors, preventing dopamine itself from binding to its receptor, thereby interfering with its function. The second mechanism through which Norsic acts is by blocking serotonin receptors, primarily one called 5HT2A. Inappropriate binding of serotonin, another signaling molecule in the brain, to the 5HT2A receptor plays a role in psychiatric disorders, such as schizophrenia, dyskinesia (difficulties with voluntary movements), and depression. It is not entirely understood how the combination of these two mechanisms results in the therapeutic effects of Norsic in Huntington’s disease patients.
Other names for this medication:
Quetiapine,
Seroquel,
Alzen,
Asicot,
Cedrina,
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Quetapel,
Quetiapin,
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Quetiazic,
Quetidin,
Quetin,
Serenil,
Setinin,
Socalm,
Vesparax,
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