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Treatment with nebulised beta-2 agonists is the initial treatment of choice in acute severe asthma and a small number of such patients require immediate intubation and ventilation. Evaluation of the effect of carbon tetrachloride poisoning on the antigen structure of the rat liver Ecological assessment of heart rate complexity: Differences between high- and low-anxious adolescents.

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However, the tumor was also immunoreactive to D2-40 and thus malignant mesothelioma could not be ruled out. A scrambled peptide showed poor lytic activity, confirming that the activity of these endosomal escape peptides is sequence specific. Simulation of prospective phytosterol intake in Germany by novel functional foods.

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The concept of a direct action of EGF on rat granulosa cells is reinforced by the demonstration of high affinity (Kd approximately 3 X 10(-10) M), low capacity (approximately 5,000 sites/cell) EGF binding sites in these cells. A layered agarose approach to fabricate depth-dependent inhomogeneity in chondrocyte-seeded constructs.

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A comparison of the microbiologic profile of indwelling versus external urinary catheters. However, this impact has never been assessed on bacteria bioluminescent models. Investigation of treatment methods in obstructive colorectal cancer. Clinical Efficacy of Mudpack Therapy in Treating Knee Osteoarthritis: A Meta-Analysis of Randomized Controlled Studies.

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Moreover, constitutive expression of virG overcame the inhibitory effect of some but not all virA alleles, suggesting that there may be more than one inhibitory mechanism. The resonance intensity of N-acetylaspartate/creatine was decreased and choline/creatine was increased, but these did not reliably discriminate between tumor grades. Distribution of vacA alleles and cagA status of Helicobacter pylori in peptic ulcer disease and non-ulcer dyspepsia.

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Dynamics of prolactin secretion from diethylstilbestrol-induced rat prolactinoma tissue in vitro. Glutathione (GSH) levels and glutathione peroxidase (GPx), superoxide dismutase (SOD), and catalase (CAT) activity were measured in the liver tissue.

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In the case of dielectrophiles C- and N-alkylation takes place to afford heterocyclic derivatives. It is essential in children and uncooperative adults and provides an immobile, quiet patient who does not recall the operative procedure. From a technical point of view there were no difficulties or complications. An optimal operating strategy for fixed-bed bioreactors used in wastewater treatment. Does washing swabs increase the efficiency of red cell recovery by cell salvage in aortic surgery?

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The results indicate that correlation equations with fewer parameters than the theoretical required to account for all molecular changes may often be encountered. cDNA sequences reveal considerable gene prediction inaccuracy in the Plasmodium falciparum genome. Smokers with MHC are differentially affected by the rise in popularity of e-cigarettes.

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Purification and properties of the pyruvate kinase isozyme M1 from the pig brain. Relationship between therapy and deliquency in epileptic patients

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CPD, nitrotyrosine, and Ki67 levels were higher in PCa than in benign and tended to co-localize, along with phospho-Stat5. Terminal duct carcinoma, at times, may be difficult, if not impossible, to distinguish from adenoid cystic carcinoma in fine-needle aspiration specimens. Melittin in concentrations as high as 100 microM did not significantly alter membrane fluidity of SYM as measured by fluorescence depolarization and electron spin resonance (ESR) using diphenylhexatriene and a doxyl derivative of SPM, respectively. Because neuronal mechanisms controlling these responses are not known, these were investigated in human neuroblastoma SH-SY5Y cells.

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Data analysis was performed using the SPSS software version 18 and associated statistical tests. This revolution in fundamental and applied therapeutics has entrained an evolution in biology and medicine.

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We did not find evidence of association of this set of diabetes risk alleles with prostate cancer. TSNA was analyzed using a gas chromatography/thermal energy analyzer (GC-TEA), while nitrate was determined spectrophotometrically as nitrite following on-line reduction with copper, diozatization with sulfanilamide and coupling with N-(1-naphthyl) ethylene diamine to form an azo dye.

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This protein showed significant similarity to the extracellular endopeptidase with beta-lactamase activity encoded by the adp gene from Bacillus cereus and to PBPs (DD-carboxypeptidases and DD-endopeptidases) and beta-lactamases. SYNTHESIS OF SOME HISTAMINE DERIVATIVES HAVING POTENTIAL HISTAMINE-LIKE OR ANTIHISTAMINE ACTIVITY. While both mutants grew more slowly than controls, the mutant deficient in tRNA(Glu2) spacers was more severely affected. The RAV-0-injected chickens also developed neoplasms at a much higher frequency than did the control chickens.

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Demyelinating encephalomyelitis associated with treatment with adalimumab VULVOVAGINITIS IN CHILDREN: AN ACCOUNT OF ITS ETIOLOGY, SYMPTOMATOLOGY AND MANAGEMENT, WITH A SUMMARY OF SIXTY-THREE CASES OCCURRING IN SOUTH AFRICA. Conversely, in vivo loss of EphA function, achieved through EphA7 gene disruption, caused a reduction in apoptosis occurring normally in forebrain neural progenitors, resulting in an increase in cortical size and, in extreme cases, exencephalic forebrain overgrowth. Rose hip extract at concentrations higher than 500 micro/m1 inhibited the chemotaxis and chemiluminescence of peripheral blood polymorphonuclear leucocytes in vitro. Isolated lymphoma of the anterior visual pathway diagnosed by optic nerve biopsy.

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The majority of these associations are with common single-nucleotide polymorphisms exhibiting modest effects on relative risk. The authors used the version of the National Eye Institute 25-item visual function questionnaire (NEI VFQ25). Influence of pudendal block on the function of the anal sphincters. Use of effective core potential calculations for the conformational and vibrational study of platinum(II) anticancer drugs. Using a 0.05-0.1 M neutral solution of barium acetate as electrolyte, thin-layer electrophoresis allowed excellent and rapid separation as well as identification of all common uronic acids which are constituents of many acidic polysaccharides.

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For most drugs, current bioequivalence testing generally enables clinicians to routinely substitute generic for innovator products. In order to better manage and make full use of such large amount of toxicity data, there is a trend to develop functionalities aiming towards data governance in predictive toxicology to formalise a set of processes to guarantee high data quality and better data management. We present an algorithm to study mixed-state dynamics in one-dimensional quantum lattice systems. An acute obturation intestinal obstruction, caused by biliary concrement The novel CBT provides reliable and reasonably accurate data for on-line GER estimate, in a simple manner suitable for medical clinics or bedside setting, without the use of radioactive substances.

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In a GWAS, single-marker analysis, which tests one SNP at a time, is usually used as the first stage to screen SNPs across the genome in order to identify a small fraction of promising SNPs with relatively low p-values for further and more focused studies. The use of eculizumab in C4d-negative or C1q-negative AMR does not seem effective.

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A wrinkle formation mechanism with cutaneous aging is addressed through a mechanical calculation of linear buckling. Precise tumor location during surgical treatment is often difficult, owing to limited tumor size and post-surgical anatomic modifications. The infrared and Raman spectra have been simulated from calculated intensities. The strains from the gastric-cancer group had a significantly higher ratio than those from the non-gastric-cancer group, although all results were below the cut-off ratio of the Ames test, and were thus regarded as having no mutagenicity.

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We suggest that fragment A passes through these pores from acidic endocytotic vesicles (lysosomes?) to the cytosol. Effect of hypothalamic lesions and hypophysectomy on corticoid production in vitro and on adrenal weight in rats. However, there was significant increase in mean serum fucose level of oral squamous cell carcinoma patients compared with healthy controls. This, along with lower side effect-related issues, has led to improved compliance and patient satisfaction.

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Effect of n-alkanes on asphaltene structuring in petroleum oils. In the current study we investigated whether selective EP ligands alter PTZ-induced seizures in adult male Wistar rats by electrographic methods.

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Value of vaginal smears in study of certain pathological pregnancies Symptoms and esophageal clearance by timed barium study were compared before and after treatment. First, the correction for the density of states is made smooth by using the Gaussian distribution obtained by a short canonical simulation. Monoepoxy octadecadienoates and monoepoxy octadecatrienoates 2: mass spectral characterization.

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The principles of the medical service, as seen in the framework of logistics The chaperone reduced the UPR and inhibited ER stress-associated proapoptotic pathways.

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An increasing discussion today consists of whether emerging genetic tests will provide a powerful tool for individual risk assessments for the life, health, disability and accident policies underwritten by private insurance companies and what could be the consequences of this for the insurance contract system built throughout the last decades. Endothelium-dependent and -independent vasorelaxation by a theophylline derivative MCPT: roles of cyclic nucleotides, potassium channel opening and phosphodiesterase inhibition.

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The patients had multiple painful neurofibromas, including bilateral orbital plexiform neurofibromas, and spinal as well as mucosal neurofibromas. At the cloud base, multiple scattering is weak and single backscattering is predominant by many orders of magnitude. Thus, comparative molecular dynamics simulations reveal how a PI-binding domain undergoes changes in conformational dynamics on binding to a PIP 2-containing membrane and how interactions additional to those with the PI headgroup are formed. The effect of the local application of cortisone, ACTH and desoxycorticosterone on epithelial regeneration in the guinea-pig cornea following mechanical erosion

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Selective propagation of such transformants, however, led to the integration of plasmid sequences into the H. One manner in which this obligate parasite regulates and adapts to its changing environment is through cyclic-di-GMP (c-di-GMP) signaling. WebPrInSeS: automated full-length clone sequence identification and verification using high-throughput sequencing data. By use of isotope substitution neutron scattering difference measurements on a 0.04 mole fraction solution of tert-butanol in water as the solute clustering passes through a temperature maximum, the changes in local intermolecular structures are examined.

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Our objective was to assess the impact (and safety) of aspirin on vascular and nonvascular outcomes in primary prevention. Between January 2003 and June 2006, we retrospectively analyzed patients who underwent surgical treatment due to parasitic cysts of the liver, at the Ege University School of Medicine, Department of General Surgery. We have previously shown that tryptophan depletion enhances punishment but not reward prediction (Cools et al. The aim of the study was to evaluate the risk of occurrence of metabolic syndrome (MS) in females who suffered from gestational diabetes mellitus (GDM). The gain in the VOR in this context refers to the linear components of the fit, and so predicts sensitivity only at low head velocities.

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Effects of A-192621.1, a specific endothelin-B antagonist, on intrarenal hemodynamic responses to endothelin-1. Intriguing is an insCGTT variant that truncates the protein at its amino terminus and results in a GRIN3B null allele. Triplet complexes typically (but not always) undergo spin crossover prior to solvent coordination, whereas 17e doublets do not coordinate solvent molecules as token ligands and cannot relax to a lower spin state to do so.

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We found that these polypeptides were particularly cysteine-rich and lost their ability to trigger host-acceptance behaviour after being denatured and purified. Blood urea nitrogen and creatinine values in the serum, and histopathological change in the kidney were utilized as indicators of nephrotoxicity caused by cis-DDP. A case report of cor pulmonale in a woman without exposure to tobacco smoke: an example of the risks of indoor wood burning. Orexin-A was microinjected into lateral preoptic area (IPOA) and the effects on sleep-wakefulness and brain temperature were studied.

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Quantitative analysis was performed by gas chromatography/mass spectrometry. In the cancer patient near the end of life, common ethical dilemmas include those dealing with artificial nutrition and hydration, truth-telling and disagreements over management plans. Parameters of sexual function were no different in women with different urodynamic diagnosis.

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Selective deprotection of terminal isopropylidene acetals and trityl ethers using HClO4 supported on silica gel. The sensitivity of this method was demonstrated in the analysis of a low-abundance enzyme, alpha1,3-N-acetylgalactosaminyltransferase, from single HT29 cells. To investigate whether supplement dietary fibre improves compliance to very low calorie diets (VLCD), a nutritional powder providing 388 kcal/day was compared with a similar preparation containing 30 plant fibre per day. Variation in the basal level of alkaline phosphatase in Coprinus lagopus wild-type strains. Repeated episodes of chronic intermittent ethanol promote insensitivity to devaluation of the reinforcing effect of ethanol.

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Both implicit time and amplitude of the cone-mediated electroretinographic (ERG) b-wave differ significantly between the C57BL/6JOlaHsd and 129S2/SvHsd inbred mouse strains. We made a restriction map of this region and correlated it with the genetic map by subcloning the uid restriction fragments into plasmids pBR322, pBR325, and pACYC177. The presence of subendometrial echogenic linear striations, a globular configuration and myometrial cysts on transvaginal ultrasound supports the diagnosis of adenomyosis.