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Sinequan (Doxepin)

Sinequan belongs to a class of drugs called tricyclic antidepressants (TCAs) that are used primarily to treat depression and anxiety. Other examples of TCAs include amitriptyline (Elavil), nortriptyline (Pamelor), desipramine (Norpramin), and several others. Depression is an all-pervasive sense of sadness and gloom. In some patients with depression, an imbalance in levels of neurotransmitters in the brain may be the cause of the depression. Neurotransmitters are chemicals that nerves use to communicate with each other. Neurotransmitters affected by Sinequan include serotonin, norepinephrine, acetylcholine, and histamine. Sinequan may elevate mood by raising the levels of serotonin and norepinephrine. It also blocks the activity of acetylcholine and histamine. The FDA approved Sinequan in March 1974.

Other names for this medication:
Doxepin, Sinequan, Adapin, Anten, Aponal, Deptran, Doneurin, Doxal, Doxin, Expan, Gilex, Mareen, Quitaxon, Silenor, Sinepin, Zonalon,

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In malacia due to chronic inflammation after tracheotomy, the cartilage is thick and irregular and the membranous portion is also thick. Its position on the human X chromosome suggests that it may be involved in X-linked mental retardation syndromes.

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Reduced microvascular adrenergic receptor activity due to opioids in endotoxin shock. nov., a fluoranthene and aflatoxin B1 degrading bacterium from contaminated soil of a former coal gas plant. Epidemiology of aplastic anemia: a prospective multicenter study. Butchering and handling of rabies virus- infected poultry may pose a potential exposure risk.

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A high level of ?-subunit was detected in neuronal and neuroendocrine tumors, including small cell carcinomas of the lung. We explore here the important questions that what the structure of tensin2 SH2 domain is, and how it binds to DLC-1, which might reveal a novel binding mode. Combined treatment approaches including resective surgery after imatinib treatment in patients with advanced metastatic disease have rarely been explored. Carcinoma of the proximal extrahepatic biliary tree radiologic assessment and therapeutic alternatives. Orthostatic hypotension in familial amyloid polyneuropathy: treatment with DL-threo-3,4-dihydroxyphenylserine.

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The genus Cataractocoris includes large waterfall-inhabiting insects that occur from Mexico to El Salvador and has received very little attention in the literature. Cassava roots are an important source of dietary and industrial carbohydrates and suffer markedly from postharvest physiological deterioration (PPD). Expression of hurpin, a serine proteinase inhibitor, in normal and pathological skin: overexpression and redistribution in psoriasis and cutaneous carcinomas.

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Morphine, pethidine or ketobemidone in acute pain--are there significant differences? An amplification unit in human melanoma cells showing partial homology with sequences of human papillomavirus type 9 and with nuclear antigen 1 of the Epstein-Barr virus. We investigated the impact of sexual stimuli and the influence of sexual motivation on the performance in a dot-probe task and a line-orientation task in a large sample of males and females.

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Halsted, and from the work of the DeBakey family in surgery and in the craft of medical writing. These results suggest that monitoring transcripts of dissimilatory (bi)sulfite reductase genes in distinct populations of sulfate reducers can provide insight into the relative rates of metabolism of different components of the sulfate-reducing community and their ability to respond to environmental perturbations. Isolation of nutritional variants from conjunctival and HeLa cells. Positive and negative inotropic effects of DL-sotalol and D-sotalol in failing and nonfailing human myocardium under physiological experimental conditions.

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The implementation of a novel imaging window as reported here enabled longitudinal microscopy of ovarian physiology and orthotopic tumor invasion. The method is sensitive, reliable, and can be well applied in this experiment. In many cases, the projection direction of the classical and extended LDA methods is not considered optimal for special applications.

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No intraoperative or postoperative maternal or fetal complications occurred. Reversal of the effects of centrally-administered morphine on colonic motility in dogs by the benzodiazepine receptor antagonist RO 15-1788. Embolization therapy was initially successful, even though the bleeding episodes became recurrent. Mice were inoculated intracerebrally with MMP-9 targeting siRNA (MMP-9 siRNA). Pharmacological inhibition or knockdown of c-Abl reduces the production of infectious HCV (J6/JFH1) particles in Huh-7.5 cells without markedly affecting viral RNA translation and replication.

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The longitudinal prevalence of MRSA in care home residents and the effectiveness of improving infection prevention knowledge and practice on colonisation using a stepped wedge study design. Investigation of product quality between extemporaneously compounded progesterone vaginal suppositories and an approved progesterone vaginal gel. This study investigated whether changes in histone acetylation, regulated by histone acetyltransferase and histone deacetylase (HDAC), are induced by renal ischemia and involved in the regenerative response.

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Since the mitotic index of the hamster epithelium exhibited a circadian rhythm, the times of sonication and tissue sampling were arranged to allow for detection of a division delay as evidenced by a change in mitotic index in cells insonated in the early S or late S/early G2 phases of the cell cycle. Moreover, renal toxicity caused by cis-DDP was enhanced significantly by a decrease in the renal GSH level by buthionine sulfoximine (BSO) pretreatment in both kinds of mice. There are no reliable clinical indicators to identify patients with white coat hypertension.

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Despite increasing terminal elimination half-life and volume of distribution at steady state (increasing drug load for a given plasma concentration), the context-sensitive half-time of piritramide after 3 days of administration is lower than predicted from bolus kinetics, making the drug a suitable candidate for intensive care unit analgesia. Comment on: Functional Outcomes of Patients with Amputation Receiving Chronic Dialysis for End-Stage Renal Disease. The chondroid regions showed a typical cartilage fine structure-of greater interest was the finding that this tissue was mixed type of both hyaline and elastic cartilage. Dynamics of matter-wave condensates with time-dependent two- and three-body interactions trapped by a linear potential in the presence of atom gain or loss. To raise the output power density of PB, a synchronized switch harvesting inductor (SSHI) is used in parallel with the harvesting structure to reverse the voltage through charge transfer between the output electrodes at the transition moments from closed-to open-circuit.

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The oxidation mechanism of Trolox C (a vitamin E analogue) by peroxidases was examined by stopped flow and ESR techniques. Post-mortem polymerase chain reaction analyses confirmed a disseminated infection with HSV-1 involving various organs and tissues but excluding the central nervous system. In the current study, we present an approach for modelling the interaction between the heart and the circulatory system. Only one patient of 18 in the premenopausal group of women with estrogen receptor-positive tumors, however, had a recurrence compared with 11 of 24 patients with estrogen receptor-negative tumors. Serrated adenomas (SA) are histologically defined by the presence of both hyperplastic and adenomatous features.

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Decreasing trend of cardiovascular mortality in Poland in the years 1980-2001 Moreover, inhibition of the p38 activity by SB203580 significantly reduces erythroid differentiation induced by TIMP-1, suggesting that the p38 MAP kinase pathway is involved in TIMP-1-induced erythroid differentiation. Age-related cataract in a randomized trial of beta-carotene in women. The properties of two-primer mixtures in which the proportions of the two primers were varied were also investigated. Over the last 10 years there has been a dramatic increase in the number of patients identified and treated with testosterone replacement therapy (TRT) for late-onset hypogonadism (LOH).

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The yeast transcription factors Pdr1p and Pdr3p regulate the expression of several genes that encode energy-dependent efflux pumps involved in multidrug resistance. Dysregulation of apoptosis is one of the most common molecular events known to be associated with the development of oral cancer. The following report describes the computed tomographic (CT) features of oncocytic papillary renal cell carcinoma (OPRCC), a new subtype. The special questionnaire was developed to collect and analyse the opinions of otorhinolaryngologists and allergologists.

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Developmental changes of transport of drugs into the brain play an important role in ontogenetic neuropharmacology. Transamination of l-cystathionine and related compounds by bovine brain glutamine transaminase. Full 3D contours for all tumors were manually outlined by one radiologist. Basal levels of plasma CORT, (ng/ml), plasma glucose (GLUC, mmol/l), thymic and splenic wet weights were subsequently determined along with complete blood counts (CBC).

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The COX-2-specific inhibitors may have an important role in extending the use of balanced, multimodal analgesia to a broad surgical population, thus ultimately improving patient outcomes after surgery. Treatment of cells with camptothecin to inhibit topoisomerase I reduced but did not abolish transcription of viral and HeLa cell genes. In this review, we discuss the state-of-the-art yeast display methodologies and the rapidly expanding set of applications afforded by this technology. With a laser wavelength of 0.69 microm and an objective lens with a numerical aperture of 0.6, three linear densities are examined: 0.35 and 0.31 microm/bit without modulation code and 0.2 microm/bit with the (1, 7) modulation code.

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Basically, there are no intrinsic limitations to the number of spins, types of interactions, sample conditions (static or spinning, powders, uniaxially oriented molecules, single crystals, or solutions), and the complexity or number of spectral dimensions for the pulse sequence. The OA group used less knee motion and higher muscle co-contraction during weight acceptance and single-limb support.

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Whole, in-shell and shelled nuts from various process operations were all positive for A. Extruded basal-cell epithelioma nodules simulating molluscum contagiosum bodies.

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In order to understand mechanisms involved in osteoporosis observed during iron overload diseases, we analyzed the impact of iron on a human osteoblast-like cell line. LGBTQ nurses expressed a need for a professional organization that would educate the nursing profession and the general population about LGBTQ issues and address their advocacy and health care policy needs. Similarly, intra-cytoplasmic A-type particle numbers increased from 98 to 184. Implementation of a rotational ultrasound biomicroscopy system equipped with a high-frequency angled needle transducer--ex vivo ultrasound imaging of porcine ocular posterior tissues.

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The investigated GBS isolates originating from infections in newborns and healthy neonates represented serotype III in more than half of the cases and differed from one another in terms of resistance to macrolides, ST type affiliation and the presence of genes encoding surface proteins from the Alp family. Longitudinal dispersivity (alpha) data were compiled from 109 different authors for different types of geological media.

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A novel non-lens betagamma-crystallin and trefoil factor complex from amphibian skin and its functional implications. Shrinkage of follicles (with increased percentage of germinative centers in them) and reduced count of mature lymphoid cells in the medullary cords indicated more intense migration of B cells from these B-dependent zones.

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The results suggest that both mu- and delta-opioid receptors can modulate the transmission of nociceptive information in the rat spinal cord. The infrared radiation information of the forearms was collected and the major axis of the moxibustion reaction area was recorded. Clinicopathologic characteristics were evaluated in 20 cases of cystosarcoma phyllodes in relation to clinical outcome.

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The process of authoring a clinical trial protocol, the document that specifies the details of the study, is usually a manual task, and thus authors may introduce subtle errors in medical and procedural content. Adaption of UCG-Lyphotest--a hemagglutination inhibition pregnancy test with human serum or plasma. The role of the N-terminal segment of CCR5 in HIV-1 Env-mediated membrane fusion and the mechanism of virus adaptation to CCR5 lacking this segment.

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Adult patients with no biologic use 6 months before TNF-blocker initiation (index) and with Health Assessment Questionnaire Disability Index (HAQ-DI) scores at index and 9-15 months after index were analyzed (218 etanercept, 93 infliximab, and 40 adalimumab). The contemplation for the salvage operations and the nonoperative treatment for the pediatric splenic injuries had increasingly been suggested as the standard case management. Mechanisms underlying the formation of the cytosine-tyrosine cross-link in nucleohistone were proposed to involve radical-radical and/or radical addition reactions of hydroxyl adduct radicals of cytosine and tyrosine moieties, forming a covalent bond between carbon 6 of cytosine and carbon 3 of tyrosine.

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In many cases this occurs by adjusting the access of the regulated species to the canonical import/export machinery. The histological diagnosis was inflammatory polyp with marked infiltration of eosinophils. Their elastic behavior was studied in the dry, swollen and stretched states, in order to check the various theoretical descriptions of these systems. This rise has been led predominantly by greater use of the second generation antipsychotic (SGA) drugs, which have a low incidence of neurological side-effects. Some results of the study of the state of the internal organs in burned subjects

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Functional asymmetry of phosphate transport and its regulation in opossum kidney cells: phosphate transport. Thus, stability and perhaps assembly of larger ESC complexes may depend on ESC phosphorylation. Due to the rapid expansion of first-line antiretroviral therapy in resource-limited settings (RLS), increasing numbers of people are living with HIV for prolonged periods of time.

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Theoretical, desirable features of second-generation metal-on-metal (MoM) hip prostheses have led to their widespread use. To demonstrate the accuracy and efficiency of this approach the binding curves for three different configurations of the benzene dimer are computed: T-shaped, sandwich, and slipped parallel.

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Although these studies demonstrated some success in tinnitus suppression, none established a link between tinnitus suppression efficacy and tinnitus-generating mechanisms. FasL-positive cells were observed in normal mammary epithelium from pregnant and lactating mice, but not in nonpregnant/virgin mouse mammary tissue. Oropharyngeal carriage and penicillin resistance of Neisseria meningitidis in primary school children in Manisa, Turkey. The main effect induced by testosterone was a decrease of UGT1B1 mRNA expression in peritubular myoid cells, whereas in Sertoli cells an increase in UGT1A1 and UGT1B1 was observed.

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After adjustment for demographic (clinic, sex, ethnicity, age), lifestyle (smoking, dietary energy/fat intake, physical activity), and physical (BMI, waist circumference) variables, the alcohol/insulin association was attenuated, but the association with lipids and blood pressure remained for high-intake categories. This uncommon pathogen may cause opportunistic infections in immunocompromised patients. This review is an update on current epidemiological status, clinical characteristics and diagnosis of cognitive complications observed during the course of HIV infection. CLINICAL CORRELATES AND EVOLUTION OF EPILEPTIC EEG FOCI IN CHILDHOOD

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Suppression of tumour growth in mice by a drug-antibody conjugate using a novel approach to linkage. Surgeon judgment and utility of transit time flow probes in coronary artery bypass grafting surgery. CSF samples were drawn at least three times a week and routine bacterial cultures and CSF analyses were done according to standard protocols. Comparatively little has been published concerning cost effectiveness of these systems.

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The giant enhancement of Raman signal near silver colloidal nanoparticles is exploited to study the Raman spectrum of Cytochrome c from Saccharomyces cerevisiae (Yeast Cytochrome c--YCc) in the limit of single-molecule. These results showed that PrKX is ubiquitously distributed and highly expressed in murine central nervous system and heart tissues in early developmental stages and in most organs at later stages but was not detected in either connective tissues or bone. Single luminal epithelial progenitors can generate prostate organoids in culture.

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Dmfs at 5 years was 5.4 (incisors included) and 7.4 at 10 years (incisors excluded, other exfoliated teeth included). Surveillance of the chest revealed cardiac tamponade and the right seventh rib fracture with left pleural effusion. Occurrence of polybrominated diphenyl ethers, polychlorinated biphenyls, and phthalates in freshwater fish from the Orge river (Ile-de France).

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Structural organization of alpha-satellite DNA in a single monkey chromosome. Hepatic arterial infusion was performed biweekly during hemodialysis and blood platinum concentrations were assessed. DNA-repair synthesis in ataxia telangiectasis lymphoblastoid cells.

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Evaluation of: Haworth O, Cernadas M, Yong R, Serhan CN, Levy BD. Diagnosis is confirmed by echocardiography and coronarography and can be precisely located by multislice CT-scan. Myelinated retinal nerve fibres are present in about seven out of 1000 elderly Chinese in northern China, without association to VA, refractive error, glaucoma and macular degeneration. These results suggest that 3-deoxyglucosone accelerates the advanced stage of the Maillard reaction and that aminoguanidine acts on 3-deoxyglucosone to inhibit its action in the advanced stage of the Maillard reaction. We report a case of malignant fibrous histiocytoma causing intravascular obstruction and include a review of the literature.

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New anti-influenza drugs inhibit virus release from infected cells. This study describes the dose response, time course, and lymphocyte requirements of procoagulant activity (PCA) induction following stimulation of thioglycolate-elicited BALB/c peritoneal macrophages with live and inactivated bacteria (Bacteroides fragilis, Escherichia coli, and Staphylococcus aureus) and murine hepatitis virus type 3 (MHV-3). The difference values of the two lesions and their respective normal bone tissue were calculated (normal density-lesion density) and compared using independent-samples t-test. In this whole cohort of depressive patients, baseline high Self-Directedness predicted higher depression scores after 4 months of treatment.

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The simple animal host Caenorhabditis elegans utilizes its nervous system to respond to diverse microbial cues, and can engage in a protective behavioral avoidance response to environmental pathogens. Of 66 babies under the age of 3 months, who were examined during a 6-month period for excessive or unusual crying, and who showed no signs spirotone uk yahoo of fever, diarrhoea, vomiting, blocked nose, skin eruptions, and difficulties with breast- or bottle-feeding, 9 had pus or mucus in the middle ear. Standard-dose ibritumomab tiuxetan combined with BEAM high-dose chemotherapy is safe and possibly more effective than BEAM alone as a conditioning regimen for ASCT in the era of rituximab-containing chemotherapy regimens.

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Despite recent advances in both prevention and treatment, cardiovascular disease remains the leading cause of mortality in the United States. A significant negative correlation was obtained between base-line firing rate and percentage depression to the autoreceptor agonist, but this correlation alone was insufficient to account for the observed differences in the drug response. terazosin side effects alcohol Superselective intraarterial infusion of cisplatin for squamous cell carcinoma of the mouth: preliminary clinical experience. Although bone tissue engineering techniques have become more and more sophisticated than in the past, natural bone healing mechanisms have not been sufficiently considered for further improvement of these techniques so far.

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This article summarizes the differential diagnosis and evaluation of persistent marked eosinophilia. Avoiding surgical mebendazole dosage india delay for patients on Plavix requiring nonelective orthopaedic surgery appears to be safe.

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Accurate and systematically improvable buy arzum firin toasters density functional theory embedding for correlated wavefunctions. Prolonged survival in osteogenic sarcoma with multiple pulmonary metastases. These excitation patterns are achieved without complicated RF pulse sequences, i.e., without the use of multi-dimensional RF pulses. Cerebrospinal fluid spectrophotometry and computerized transverse axial tomography (EMI scanning) in cerebrovascular diseases. Although most aspirates provide diagnostic cytology, some are classified as indeterminate.

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From 1992 to 2007, the mean level of TC increased in both men and women. Therefore, we suggest life-time follow up for every patient with breast cancer. COPLOW diagnosed the tissue as an orbital conjunctival inclusion cyst and para que sirve el medicamento ranitidina 300 mg an acquired orbital osteosarcoma. After docking screening of about 80,000 compounds, 58 high-ranked hits were selected and their activities were examined by in vitro and cell-based -1 frameshifting assays. Its specific biological activity on these cells is more than five times greater than that of insulin.

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Nonspecific epilepsy gabapentin starting dose for anxiety syndromes have been associated with this genetic disorder. VN/1203 was also able to disseminate to multiple organs, including the brain, which correlated with changes in the expression of genes associated with hematological functions and lipoxin biogenesis and signaling.

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Regarding the fermentation performances, the sugarcane juices 300 mg gabapentin high feeling with the highest magnesium concentration showed the highest ethanol yield. PET imaging of musculoskeletal tumours with fluorine-18 alpha-methyltyrosine: comparison with fluorine-18 fluorodeoxyglucose PET. The Understanding Suicidal Patients scale together with additional questions reflecting training and the psychiatric treatment of suicide attempters were administered. We discuss the use of magnetic resonance imaging (MRI) to reveal early fetal neurological involvement of cytomegalovirus (CMV) infection. This review will discuss the increased prevalence and prognostic implications of cardiovascular co-morbidities in patients with COPD.

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Because (18)F-SKI696 has been taken up in vivo by tumors that overexpress Bcr-Abl, we are exploring a possible role for identifying tumors that will respond to imatinib before therapy. For an optical implementation, a holographic contentaddressable memory is bactrim ds dosage for small dog used. Peripheral lymphocoele is a recognized complication after various forms of surgery. The recombinant plasmid was used as a hybridization probe to isolate the corresponding wild-type DNA sequence of R.

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In this study, overall PET-CT N1 status has low positive and negative predictive value for overall pN status. No recycling spironolattone 25 mg was seen when doses of naltrexone in excess of 90:1 naltrexone:carfentanil were used. There was no significant difference in complication rates between groups. Two types of switched systems are studied respectively: one is the stochastic switched delayed GRNs with only stable subsystems and the other is the stochastic switched delayed GRNs with both stable and unstable subsystems.

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Evaluation of an intraoperative ultrasound training model based on a cadaveric sheep brain. The small parsimony problem is polynomial-time solvable for phylogenetic trees. We have examined the feasibility of using Xenopus laevis oocytes microinjected with rabbit poxvirus as a system to study poxvirus gene l albenza price expression. The objectives of this study were to (i) describe the reporting of contextual factors in the literature on the effectiveness of quality improvement strategies, (ii) assess the relationship between effectiveness and contextual factors, and (iii) analyse the importance of contextual factors.