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Coronary artery bifurcation biomechanics and implications for interventional strategies. The PP110 film-based formulation provides a slow-release mechanism and as a consequence, a prolonged therapeutic window.

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Dietary trans fatty acids and their impact on plasma lipoproteins. The overall survival of patients with ESCC was slightly better than patients with SCLC.

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Advancement biological target therapy of nasopharyngeal carcinoma Elevated preoperative serum CA 125 levels were more predictive of malignancy in postmenopausal than in premenopausal women (0.86 vs 0.67), but normal levels did not preclude malignancy in either group. Investigations on the presence of antibodies to papova viruses in patients with different forms of cancer and in other categories of patients or apparently healthy subjects.

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Hydrodynamic image formation by the peripheral lateral line system of the Lake Michigan mottled sculpin, Cottus bairdi. Air pollution in the city of Tehran has been a major problem for the past three decades. Therapeutic, PRP gel is produced from patient blood utilizing autologous platelets and plasma that contribute growth factors, cytokines, and chemokines, in a fibrin matrix.

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It must be assumed that even low-dosage irradiation of the liver which fails to produce measurable changes at the beginning, may influence the structure and function of the hepatic parenchyma. Health promotion education can play a key role in the achievement of optimal health and well-being for this population. When deprived of calcium the slow striated muscle fibers of the frog develop reversible contractures in either hypertonic or isotonic solutions. The genotypic characterization of fluoroquinolone resistance using Luminex was also consistent with the data on phenotypical resistance obtained by microdilution test. Alpha 2 and beta adrenoceptors, and muscarinic cholinoceptors in 2 brain regions (cerebral cortex and hippocampus) were measured in rats which received either tap water or nicotine added to the drinking water (5-8 mg/kg/day) for 4 weeks, and immobilization stress (daily 2 hr) for the last 5 days.

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Red fluorescent Qdots 605 were selected because autofluorescence of cells in the red spectral range is not relevant. Even if only comparatively few are brought to the attention of the physician, they account for a considerable portion of the reasons for seeking medical care, both in acute and chronic conditions.

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A series of homologous omega-phenylalkanoic acids and omega-phenylalkenoic acids were isolated from seed lipids of various genera of the subfamily Aroideae of Araceae (the Jack-in-the-Pulpit family) and characterized. The protein increases the energies required for this stretch through the electric field it generates near the active site. Knowledge of this muscle, its anatomical location and variations, and its magnetic resonance imaging characteristics may help clinicians make an accurate differential diagnosis. In order to place appropriate restrictions upon the availability of certain therapeutic agents to limit their abuse, it is important to assess abuse liability, an important aspect of drug safety evaluation.

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The location of the visual field defect correlated with the location of the infusion cannula. There, only a fine meshwork of stained thin fibers and perisomatic terminal arborizations, and also some isolated perikarya of NADPH-d stained multipolar MTN neurons, were observed. Association of HLA-DRB alleles and pulmonary tuberculosis in North Chinese patients.

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The relative merits of coronary perfusion and cold arrest of the heart are discussed together with the disadvantages of each technique. An algorithm that detects overrepresentation of these signature genes in a gene group of interest is used to infer the signaling pathway responsible for regulation.

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Pyrophosphate analogues as inhibitors of DNA polymerases of cytomegalovirus, herpes simplex virus and cellular origin. Adolescence represents a critical period for brain development and the endocannabinoid system plays a crucial role in the regulation of neuronal refinement during this period. Phase II study of cetrorelix, a luteinizing hormone-releasing hormone antagonist in patients with platinum-resistant ovarian cancer.

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In the 1st trimester of pregnancy the demonstration of the gestational sac and of an embryo is most important. Binding motifs for MHC Class II appear to contain up to four anchor positions, with more loosely defined amino acid preferences.

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Although a single binary functional complex between cytochrome P450 (P450 or CYP for a specific isoform) and cytochrome P450 reductase (CPR) has been generally accepted in the literature, this simple model failed to explain the experimentally observed catalytic activity of recombinant CYP2E1 in dependence on the total concentration of the added CPR-K56Q mutant. Burn scar assessment: A systematic review of objective scar assessment tools. Conformational analysis by atomic force microscopy (AFM) of the dried material showed that the polysaccharide forms pearl-necklace-like, intramolecularly condensed structures when dissolved in Milli-Q water and partially relaxed helical aggregates when in alkali solution.

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It exhibited good convergent and discriminant validity but poor predictive validity. MDMA induced a slight dose-dependent impairment on psychomotor performance. As far as concerns the mesenchymal cells, some cells of dental papilla in contact with enamel organ, are intensely positive. Detection of Raman spectra in ocular drugs for potential in vivo application of Raman spectroscopy. Key practical steps in establishing such a programme are discussed, and the experience from Lubombo is used to demonstrate the steps in performing a health needs assessment in a developing country.

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The concentrations of DOPAC and NE in the cortex of both --D and D replete rats increased significantly compared to normal diet group. And while there is a small body of evidence emerging around this phenomenon commonly known as medical tourism there remain significant unanswered policy and research questions which need to be addressed. In conventional silicone oil, the microorganisms survived longer than in heavy silicone oil. With increasing noise amplitude, further transition to classical behavior is shown through an accurate quantitative analysis, which demonstrates that both the energy growth and the momentum distributions are reaching their classical limits. However, the difference in scapular upward rotation between pitchers and position players is not known.

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Impaired fibrinolysis as a result of increased plasminogen activator inhibitor-1 (PAI-1) levels in plasma is a common finding in patients with deep vein thrombosis (DVT). 15 male patients with mean age 33.7 years (range 18 - 56 years) of post traumatic tibial bone loss were analysed.

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Nissen fundoplication cured reflux in all patients up to 2 years, but 5 per cent required revisional surgery. These multivalent ligands are simple to synthesize, are highly soluble, and can be either homofunctional or heterofunctional. Similar source of differential blood mRNAs in lung cancer and pulmonary inflammatory diseases: calls for improved strategy for identifying cancer-specific biomarkers. Evaluation of myocardial contractility by the non-invasive method. Occupational progressive systemic sclerodermia caused by a quartz-containing scouring agent

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Circulating fibrinolysin in a case of prostatic carcinoma with bony metastases. Anti-B.pertussis fimbria IgG antibody levels were also high by both ELISA and microagglutination tests. Individualizing MMF dosing based on MPA determinations may minimize the risk of rejection following OHT.

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Helical arrays of dimers were used to construct a three-dimensional membrane model, which matches the packing lattice deduced from electron microscope analysis of the tubular dimer-only membranes found in mutants of Rba. Using TK-ts13 cells transfected with a plasmid containing the thymidine kinase gene under the control of the human 2.8 kb PCNA promoter, we demonstrated that this promoter is not regulated by calmodulin. Cancer cells in the advanced stage show aberrant antioxidant capacity to detoxify excessive ROS resulting in the compensation for intrinsic oxidative stress and therapeutic resistance. Batrachochytrium dendrobatidis (Bd), the cause of a fatal fungal skin disease of amphibians that has led to massive die-offs, global declines and extinctions, has spread internationally as a pandemic clone with low genetic diversity.

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Serum oestradiol and SHBG levels were significantly higher after 10 years of transdermal oestradiol, alone or combined with micronized oral progesterone, without differences observed in serum metabolic parameters. It is shown that the photolysis is dependent upon light in the region 450-320 nm. In stress conditions, microspores and young pollen grains can be switched from their normal pollen development toward an embryogenic pathway via a process called androgenesis. The digitization of PAD processes has facilitated the evaluation of real-life ALS care.

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Remarkably, only four minor changes in the bacterial progenitor, representing one gene gain and three gene losses, enabled transmission by flea vectors. THE AMERICAN BOARD OF FAMILY MEDICINE FOUNDATION INAUGURATES THE G. Epstein-Barr virus infections in males with the X-linked lymphoproliferative syndrome. Endogamy and anthropological differentiation in the Canary Islands.

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As we prepare to enter the much-heralded post-genomic era, we also need to revisit our overall models of the relationship between genotype and phenotype to encompass aspects of genome structure and composition beyond structural genes. Thus, viral resistance becomes a challenge for intervention to prevent mother-to-infant transmission. A new method for the reparation of cast crowns with functional technique occlusal surfaces. Their helical structures might permit targeting of the backbone loops and grooves of G-quadruplexes instead of the G-tetrads.

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people living in the Bella Coola Valley, Canada, and having a chart at the Bella Coola Medical Clinic as at September 2001. We discuss data requirements for answering questions related to tag loss and sampling designs that lend themselves to this purpose. Fifty-three patients with measurable disease received capecitabine 1,000 mg/m2 twice daily on d 1-14 and oxaliplatin 130 mg/m2 on d 1, every 3 wk. A critical evaluation of the open and closed methods of determination of oxygen consumption after a change in inspiratory oxygen concentration All of the efflux systems extrude a wide variety of antimicrobial agent groups, i.e., quinolones, macrolides, tetracyclines, lincomycin, chloramphenicol, most penicillins (all but carbenicillin and sulbenicillin), most cephems (all but cefsulodin and ceftazidime), meropenem, and S-4661, but none of them extrude polymyxin B or imipenem.

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cis-acting elements responsible for interleukin-6 inducible C-reactive protein gene expression. Clinical symptoms were recorded and laboratory and radiologic examinations were carried out. Atypical fibrosarcoma in the skin of a Roborovski hamster (Phodopus roborovskii). A convenience sample of families presenting to an urban primary care clinic for routine care filled out an anonymous, voluntary survey that included demographic data, the Satisfaction with Life Scale (SWLS), the Spiritual Inventory and Beliefs Scale, and an emotional coping inventory.

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However the PinG model predicts significantly different contributions of the 18 sources to pollutant concentrations and deposition downwind of the point sources compared to the base model. Compared with metal stent, silicone Y-shaped tracheobronchial stent needs much more time for insertion. The stronger reactivity of polyclonal antibodies to COX subunits II-III and VIIbc with type I as compared to type II fibres, correlated well with the higher histochemical reactivity of NADH dehydrogenase, succinate dehydrogenase and cytochrome c oxidase in type I fibres. Longitudinal strain and torsion assessed by two-dimensional speckle tracking correlate with the serum level of tissue inhibitor of matrix metalloproteinase-1, a marker of myocardial fibrosis, in patients with hypertension. Rapid repletion of brain serotonin in malnourished corn-fed rats following L-tryptophan injection.

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Generally, microarray data revealed that the expression of the majority of genes remained unchanged compared to the control. Introduction: selection of 3 998 persons for screening and nephrological examination (55.7 percent), including a control group (16.1 percent). From a 2006-2007 nationally representative survey, we identified 1,111 practicing primary care physicians who provide breast and cervical cancer screenings and assessed their recommendations using clinical vignettes related to screening initiation, frequency, and cessation. This finding, together the identification of significant similarities of domain D with the preceding domain C, may help to understand the molecular mechanism by which PhK alpha and/or beta domain D might regulate PhK activity.

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IR of adipose and skeletal muscle tissue, and the elevation in insulin levels in obese, insulin-resistant patients could be explained by an adaptation to their carbohydrate intake. The cercopithecid assemblage is most consistent with a woodland habitat, corroborating an earlier interpretation based on the non-primate fauna.

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Psychosocial aspects of breast cancer treatment in Accra, Ghana. Impact on quality of life of botulinum toxin treatments for essential blepharospasm. This study investigated the sleep-promoting, thermoregulatory, and circadian phase-shifting actions of passive body heating (PBH) in elderly insomniac patients (IPs) with mild-to-moderate vascular dementia. Laminoplasty is better of laminectomy in cervical stenotic myelopathy: myth or truth? It is scarcely photo-oxidized by interaction with the mentioned ROS.

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The 29 symptoms version of the SOMS-2 with a cut-off of 4 showed a high specificity and sensitivity, being reliable as a referral tool for further specialized diagnosis. Overcoming drug resistance to heme-targeted antimalarials by systematic side chain variation of 7-chloro-4-aminoquinolines. The characteristic shape of the isochrone is a trifurcated system: Trajectories that transmit the barrier are launched from the lower branch (T), while the middle and upper branches form the segments for reflected trajectories (F and B). While RA FLS express the FKN receptor, CX(3)CR1, the pathophysiologic relevance of FKN stimulation of RA FLS is not understood.

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Death was further correlated with active AAV2 genome replication and differential expression of viral non-structural proteins Rep78 and Rep52. It is not possible at present to make any specific recommendations for prophylaxis. A minor decrease in kidney function was observed in most patients, but none of the surviving patients needed hemodialysis. Because of the complexity of transfusion risks and practices, the cost-effectiveness of whole blood or PLTs-and-plasma PRT can be modeled provided that assumptions and simplifications are made. We will discuss a potential role of percutaneous vertebroplasty (PVP) in the management of patients with severe fibrous dysplasia of the spine with multiple cervical lesions and C2-C3 pathologic fractures that may not be a good surgical candidate.

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Mucocutaneous biopsy specimens consistently showed multiple dystrophic keratinocytes. Immunohistochemistry studies have confirmed the presence of group IIA, group V and group X secretory phospholipase A2 in human or mouse atherosclerotic lesions.

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Water skiing and wakeboarding are popular sports with high potential for injury due to rapid boat acceleration, lack of protective gear, and waterway obstacles. Antioxidant enzymes significantly decreased 3 h after menadione bisulfite adduct injection. Our results suggest that hydroxyurea acts during erythroid development and modulates adhesion receptor expression and function differently, possibly by acting on gene expression and the signaling cascade leading to receptor activation.

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Preincubation with Gal-3 primed neutrophils to the effects of sFbg, resulting in a synergistic action on degranulation. The two assays were used to analyze fractions obtained by gel filtration as well as serum samples serially collected from four other MI patients. To determine the levels of pro-inflammatory and anti-inflammatory cytokines in the vagina of healthy women and in bacterial vaginosis (BV) patients.

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Victims of domestic violence presenting for health care are frequently referred to medical specialists, but little is known about domestic violence screening among specialists. Remodeling of collagen fibrils due to the forces exerted by embedded cells was imaged in real-time as cells adhere to and contract the matrix. These include primary and secondary breast lymphoma, primary axillary nodal lymphoma, metastatic acute lymphatic leukemia, metastatic plasmacytoma, granulocytic sarcoma, primary angiosarcoma, metastatic rhabdomyosarcoma, hematogenous metastasis from primary lung, ovarian, cervical, thyroid, and colonic carcinoma, malignant melanoma, carcinoma of the nasal cavity, and adenocarcinoma of unknown primary. This approach has successfully resulted in decreased morbidity in these patients as well as others with limited oral opening.

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A total of 805 patients with multiple or recurrent high-grade Ta, T1, and/or carcinoma in situ bladder cancer received BCG therapy. Here, we propose an effective approach to achieve correct 3D shape measurement that can be extended in case of cells having concave surfaces, thus overcoming the limit of the previous technique. It was confirmed that the sintered hydroxyapatite had good compatibility and long-term stability with skin tissue. Lactate favours the dissociation of skeletal muscle 6-phosphofructo-1-kinase tetramers down-regulating the enzyme and muscle glycolysis. Effect of erythromycin on metabolism of quetiapine in Chinese suffering from schizophrenia.

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The GNB3 C825T polymorphism was determined by polymerase chain reaction and restriction enzyme digestion. The methylenindene scaffold can be prepared from readily available gem-dibromoolefins using an efficient palladium-catalyzed tandem intermolecular Suzuki/intramolecular Heck reaction.