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Telaprevir (Ribavirin)

Telaprevir is a high-class antiviral medicine which is taken to treat such diseases as severe RSV infection, hepatitis C infection (used in conjunction with sofusbuvir or peginterferon alfa-2b or peginterferon alfa-2a) and other viral infections. Rebetol is an anti-viral drug indicated for severe RSV infection, hepatitis C infection and other viral infections. Rebetol is manufactured by Merck Sharp and Dome (a subsidary of Merck and Co., Inc.). The active ingredient, Telaprevir is a professional grade drug, which when metabolized resembles purine RNA nucleotides. In this form it interferes with RNA metabolism required for replication Rebetol. Telaprevir helps the immune system fight the virus and makes it harder for the virus to reproduce within the body. Rebetol is prescribed in combination with other medications such as sofusbuvir and peginterferon alfa 2a/2b for preventing hepatitis C virus (HCV) cells from multiplying in your body. Treatment of HCV genotypes 1, 2, 3 and 4 is possible with Rebetol, however it is never used on its own.

Other names for this medication:
Ribavirin, Rebetol, Copegus, Alfater, Beclabuvir, Boceprevir, Daclatasvir, Daklinza, Dasabuvir, Elbasvir, Filibuvir, Hepcinat, Hepcvir, Incivek, Kipferon, Ledifos, Ledipasvir, Miravirsen, Multiferon, Olysio, Ombitasvir, Paritaprevir, Pegasys, Pegetron, Pegintron, Rebetron, Resof, Setrobuvir, Simeprevir, Sofab, Sofovir, Sovaldi, Sylatron, Technivie, Telaprevir, Veldona, Victrelis, Viroclear, Zepatier,

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Therefore, elucidating the exact compositional requirements for yeast prion formation has proven challenging. Meprobamate-antihistaminic combination as a pre-anesthetic medication for surgical patients The soluble c-type cytochromes from the bacterium Aquaspirillum itersonii. Inotropic therapy consists primarily of the administration of adrenergic agents. Although poorly understood, it has long been recognized that host regulation of virus-associated disease severity is multigenic.

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Based on a promising pilot study conducted prior to this RCT, subjects in the Tai-chi intervention group are expected to be protected against deterioration of motor coordination and interpersonal functioning. Three methods for determining the lateralization of memory functions in patients with pharmacologically resistant intractable partial epilepsy were compared and evaluated. RESULTS from replica plating suggested one of the plasmids could be related to the gene responsible for ampicillin resistance. These techniques are helpful but not perfect measures for predicting hay fever outcomes in epidemiologic studies. Our results suggest that the interactions of T antigen with ATP that are involved in T-antigen DNA binding and DNA helicase activities are different.

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Sex and workstyle of leaders and followers: determinants of productivity. Mortality from varicella in children receiving adrenocorticosteroids and adrenocorticotropin.

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There are considerable reciprocal interactions between the NE, DA, and the 5-HT systems. A simultaneous resection of a concomitant abdominal aortic aneurysm and hepatocellular carcinoma: two cases. Acute hemodynamic responses to intravenous and intra-arterial guanethidine.

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Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) is caused by mutations in the alpha4 subunit of the neuronal nicotinic acetylcholine receptor (CHRNA4) gene, mapping on chromosome 20q13.2. Childhood victimization and lifetime revictimization were assessed using the Traumatic Life Events Questionnaire. Pharmacokinetic parameters after single and multiple doses were investigated. Porcine NICC were transfected with 5 pairs of designed siRNA respectively or in different combinations with lipofectamine 2000.

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The long-term outcome in two females with autism spectrum disorder. Here, sites of apoA-I, A-II, and H mRNA and protein accumulation were determined in mouse fetal lungs by in situ hybridization and immunohistochemistry in late gestation. Preparation and in vivo evaluation of novel linkers for 211At labeling of proteins. The study also explored the extent to which parents with low and high intentions to self-check restraints differed on salient beliefs regarding the behavior.

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In addition, chronic hepatitis, cirrhosis, biliary cancer and amyloidosis sometimes occur. Future prospective studies are required to investigate this hypothesis. Compared with traditional acupuncture, acupotomology makes modern interpretations on the theory of muscle regions, absorbs theories of anatomy and pathology as well as techniques of asepsis and anaesthesia. The 1959 influenza in hospitalized military personnel in the Hopital Ste-Foy, Quebec These results indicate that the tetrapod parathyroid gland and the gills of fish are evolutionarily related structures, and that the parathyroid likely came into being as a result of the transformation of the gills during tetrapod evolution.

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Breast cancer awareness among women in Eastern China: a cross-sectional study. THE DOUBLE SACCHAROSE COMPARTMENT TECHNIC: A METHOD FOR STUDYING THE MEMBRANE POTENTIAL AND MEMBRANE PROPERTIES OF SMOOTH MUSCLE In 18 cases the invaded lesions of postcricoid area include the mucous layer, submucous fat layer and the mucous layer of anterior wall. To establish the effect on JSW reproducibility of a new method of magnification measurement in microfocal radiographs. Molecular mimicry theory is based on similarities between HLA-B27 molecule and microbial particle.

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However, at the assessment at a mean of 15 months thereafter, none of these patients were treated for carpal tunnel syndrome, although, five of them still suffered from similar symptoms. Immunohistochemical stainings of the tumor cells demonstrated positive reactions for cytokeratins and epithelial membrane antigen. MICROBIOLOGICAL SCREENING OF CHEMICALS FOR POTENTIAL ANTITUMOR ACTIVITY. The conceptual model provides structure to a process that is frequently stressful for both patients and psychiatrists.

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There was a negative correlation between the prescription of tricyclic antidepressants, selective serotonin reuptake inhibitors, antipsychotics, antimanic drugs and non-opiate analgesics and a decline in elderly suicide rates due to poisoning by solid and liquid substances, hanging, strangulation and suffocation, drowning, firearms and explosives, and jumping from high places. Diethyldithiocarbamate delays gastric emptying and increases gastric acidity in rats in vivo. Cells expressing A1-BP showed an increased virus binding capacity, but not BP-A1.

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An analysis of GABA receptor changes in the discrete regions of mouse brain after acute and chronic treatments with morphine. Therefore, we decided to complete our previous studies with further experiments using another compound of the cyanobiphenyls series, the 6CB in the nematic phase, and also on liquid substrates, water and glycerol.

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To define the kinematic motion patterns of the canine cervical spine, with a particular emphasis on identifying differences between the cranial (C(2)-C(4)) and caudal (C(5)-C(7)) segments, and to determine the significance of coupled motions (CM) in the canine cervical spine. A 65-year-old man presented with right arm and face weakness associated with severe coughing fits. Electrophysiological evaluation confirmed an isolated axillary nerve injury. Study of the neuroprotective effects of memantine in patients with mild to moderate ischemic stroke. Estrogens and progestins alter electrical and chemical features of nerve cells, particularly in hypothalamus.

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Finally, a large group of genes was up-regulated during germination on water, but not during osmopriming. Experimental staphylococcal mastitis in the mouse: effects of extracellular products and whole bacterial cells from a high-virulence and a low-virulence strain of Staphylococcus aureus. Suppression of human and mouse Th17 differentiation and autoimmunity by an endogenous Interleukin 23 receptor cytokine-binding homology region. Group III consisted of 13 patients without arthrotic changes in the wrist. Reservations on the analogy between the various leukemic diseases and their cumulative inclusion in the chapter of neoplasms

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Comprehensive cardiovascular magnetic resonance for diagnosis of cardiac hydatid cyst. The Stanford Health Assessment Questionnaire Disability Index (HAQ) is the gold standard functional status questionnaire in rheumatology, but it is lengthy. Dyslipidemia and progression of cardiovascular calcification (CVC) in patients with end-stage renal disease (ESRD).

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This late phase myocarditis is characterized by the emergence of mononuclear cells within healing foci of myocyte necrosis as well as a distinctive diffuse interstitial pattern of myocarditis. Simultaneous chemical stimulation of the hypothalamus and dorsal hippocampus in the waking cat. Different 2D fingerprints were used as search tools and also as descriptors for a support vector machine (SVM) algorithm. Disorders of the inhibitory glycine receptor: the spastic mouse. Several alterations are present in the hypothalamic hypophyseal regulation of many hormones in patients with chronic renal failure.

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After 10 years, dental ankylosis of the incisor was recorded and the patient underwent a prosthetic-orthodontic rehabilitation using CAD-CAM technology and no-prep veneers. Significant differences in the starting amount of target cDNA were found between the analyzed genotypes, indicating differences in viral accumulation that correlated to their different levels of resistance. Vardenafil, a clinically available phosphodiesterase inhibitor, potentiates the killing effect of EGCG on CLL cells.

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Three-dimensional analysis showed that the truncated protein had lost the functional region for both ATP and substrate binding such that tyrosine kinase activity would be affected. Inferred threat and safety: symbolic generalization of human avoidance learning. The outcome of this case study suggests that customized multidensity foot orthoses may be a useful intervention to reduce foot pain and maintain function in the neuroischemic diabetic foot. The micelle diameter and pyrene partition coefficient (Kv) were directly related to the PCL block length whereas the critical micelle concentrations (CMC) were inversely related to the PCL block length.

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Here, we show by immunohistochemistry and in situ hybridization that Gal1 expression is differentially regulated by peripheral nerve injury and by dorsal rhizotomy. Doxorubicin induces expression of multidrug resistance-associated protein 1 in human small cell lung cancer cell lines by the c-jun N-terminal kinase pathway. Examination of the Association between Insufficient Sleep and Cardiovascular Disease and Diabetes by Race/Ethnicity. Hence, adsorption experiments of creatinine/creatine binary mixture were also carried out to investigate and confirm the specific binding of the creatinine-imprinted poly(beta-cyclodextrin) towards creatinine.

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Managed carefully from childhood to adulthood patients should not require ventilatory assistance. Effect of the South African traditional meat, biltong, on cancer-associated enzymes CYP2E1 and CYP1A2. Assuming that the dependence parameter is known, at the second stage we estimate the marginal hazard function by iterating between estimation of the risk heterogeneity (frailty) for each family and maximization of the partial likelihood function with an offset to account for the risk heterogeneity. The subjects involved were 40 patients with various stages of chronic heart failure.

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Palmitic acid stimulated the enzyme by 18 percent at its optimum pH (5) but the stimulation was in excess of 63 percent at pH 2.5. Athletic performance and serial weight changes during 12- and 24-hour ultra-marathons. A critical review of medical mycology in the United States 1946-1956 solium cysticercosis were investigated in pork carcasses slaughtered and retailed in Antananarivo (Madagascar), thanks to a 12-month monitoring plan in two urban abattoirs.

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Association of nuclear-localized Nemo-like kinase with heat-shock protein 27 inhibits apoptosis in human breast cancer cells. Patients having emergent surgery after chemotherapy have more comorbidities and severe disease, which are associated with higher complication rates and mortality. The risk of experiencing long GP referral delays was associated with residential area, with a greater risk of long delays in rural vs.

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The sustained effects of acupuncture have been widely applied to clinical treatment, thus it can be assumed that the relatively functional specificity of acupoints may evolve as the function of time. Initially, DC-based therapy was used in animal models of cancers. Differential associations of serum amyloid A and pentraxin-3 with allele-specific lipoprotein(a) levels in African Americans and Caucasians. Image integration for catheter ablation: searching for the perfect match.

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Epidemiologic studies suggest that a high level of physical activity would protect against coronary heart disease. On principles for otolaryngological endoscopy and a technic for ear endoscopy Despite the positive attitude of nursing students toward technology, the problem of minimal technology education should be addressed in future nursing programs to further enhance positive attitudes toward technology. Esterification of (4--14C)cholesterol by cutaneous bacteria (Staphylococcus epidermidis, Propionibacterium acnes, and Propionibacterium granulosum).

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The assumption of PKA being one molecular entity has hindered the study of a wide range of behaviors. Stem cell therapy has been studied intensively as a promising therapeutic strategy toward a cure for diabetes. In particular, the program is used here to make predictions on the behavior of cells grown in a glucose-poor medium: these predictions are confirmed by experimental observation. Retroperitoneal laparoscopic dismembered pyeloplasty was feasible in all cases. Prenatal sonography provides the radiologist a means to identify congenital cystic adenomatoid malformations in a population of infants who are asymptomatic at birth.

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VWF is synthesized with a very large propeptide (VWFpp) that is critical for intracellular processing of VWF. Nerve rootlets to be sectioned for spasticity resolution in selective dorsal rhizotomy. Spending for drugs, hospitalizations, and physician services was compared for COPD patients with and without prescription coverage using data from the 1999 and 2000 US Medicare Current Beneficiary Survey.

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Immunologic mechanisms in chronic demyelinating diseases of the central and peripheral nervous system. Studies on the in vivo absorption of butyric acid in the small intestine of the cat. Effect of intrahepatic arterial infusion of 131I-labelled lipiodol on hepatocellular carcinoma of rat. NEW DATA ON THE BLOOD AMMONIA IN A FRESH WATER TELEOSTEAN: CYPRINUS CARPIO L MHC class I molecules were engineered with a rigid, in-sequence, YFP tag followed at the C-terminus by a pair of crosslinkable domains.

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Isolation of a terminal cisterna protein which may link the dihydropyridine receptor to the junctional foot protein in skeletal muscle. Highly sensitive transient absorption imaging of graphene and graphene oxide in living cells and circulating blood.

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ON THE CLINICAL ASPECTS AND SURGICAL TREATMENT OF ENDEMIC GOITER Insulin-like growth factor 1 (IGF-1) is a crucial mediator of body size and bone mass during growth and development. The effect of dialysis on platelet function of patients with renal failure. Ultrastructurally, all seven cases were confirmed to be myofibroblastic in nature, and the morphology and intracellular topography of the inclusion bodies suggested their derivation from contractile protein. We have been unable to determine a clinical value for serum anti-EBNA-1 IgG levels in MS or to confirm reported association with disease course and clinical disease activity.

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Delta opiate receptors are involved in the endopioid-induced myoclonic contractions. One patient with osteomyelitis of the anterior tibial tubercle and a second patient with arteriovenous malformation of the anterior tibial tubercle were originally misdiagnosed as having Osgood-Schlatter disease.

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Blood samples, demographic and cultural data were collected from seven settlements of Semai Senoi, a swidden farming ethnic group of Malaysia. Nalbuphine is a newer drug which, like pentazocine, is an opioid agonist-antagonist. Hypercalcemia and malignant disease in the elderly: magnesium sulphate therapy.

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Although the use of screening mammography has increased over the past decade, older women are one of the last subgroups to derive benefit from this screening test. Recent research has emphasized that the human circadian rhythm system is differentially sensitive to short wavelength light. Maternal history of asthma or atopy is among the most consistently reported risk factors for asthma and atopy in children, yet the molecular basis for this observation remains unclear.

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Effectiveness of structured teaching on home care management of diabetes mellitus. Haemostasis prophylaxis using single dose desmopressin acetate and extended use epsilon aminocaproic acid for adenotonsillectomy in patients with type 1 von Willebrand disease. These results indicate that the jun oncoprotein binds the same DNA sequences as GCN4, and strongly suggest that jun is derived from a normal cellular transcription factor (possibly AP-1, which recognizes similar sequences).

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Onychomatricoma is a rare benign tumor originating in the nail matrix. We found that folds shared by the three organismal domains were placed almost exclusively at the base of the rooted tree and that there were marked heterogeneities in fold distribution and clear evolutionary patterns related to protein architecture and organismal diversification. One of the primary goals was to enhance the communication between paraprofessional (nursing assistants) and professional (nurses and physicians) staff. In 2005 the concept of healthcare associated pneumonia (HCAP) was proposed by the ATS/IDSA guidelines. On the 150 anniversary of the French chemists who marked the bacteriological era

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This was confirmed by fractionation of infected cells in the presence or absence of detergent. Diffusion values normalized after 10 days of normoxia (hypoxia from P10 to P20 and killed at P30 (early hypoxia P30)), but immunohistochemistry revealed significant astrocytosis and hypomyelination. Using cultured chick Bergmann glia cells and mouse cerebellar fusiform astrocytes, we demonstrate here that glutamate receptor activation results in a time and dose dependent decrease of Dp-71 levels.

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Compared to avoiders, planners had better executive function, were more psychologically and physiologically reactive and performed better on the BPST. FE patients without schizophrenia were no different in any parameter as compared to controls.

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To determine whether a skills laboratory for corneal foreign body and rust ring removal improves self-assessed skill and confidence. This will have a significant impact in the future development of targeted asthma therapies as well as the current management of asthma and other inflammatory medical conditions. Therefore, if changing redox conditions facilitated animal diversification, it did so through a limited rise in oxygen past critical functional and ecological thresholds, as is seen in modern oxygen minimum zone benthic animal communities.

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Laboratory studies of the frequency of mutation to drug resistance and the features of drug-resistant mutants may have predictive value for the clinic. Limited access to hospitalization in an Italian infectious disease ward. Some symptoms showed marked change in prevalence over time (e.g., worry, irritability, fatigue), whereas others showed no change (e.g., loss of enjoyment, worthlessness). No significant differences were noted in the current study in several preoperative variables and surgical outcomes between AA and C. A migratory third molar erupting into the lower border of orbit causing blindness in the left eye.

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This association of MR and gpmcrD did not withstand zolax medicine man polyacrylamide gel electrophoresis under nondenaturing conditions. Experimental studies on biomechanics of articular process fractures Musculoskeletal pain associated with corticosteroid therapy in cancer. Family communication patterns moderate the relationship between psychological reactance and willingness to talk about organ donation. Both PG12 and EDRF are readily degraded by free radicals, especially superoxide anion.

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Data were analyzed in SPSS software, by descriptive and analytic statistics and p value 0.05 was considered statistically significant. We report that dendritic cells in these mice taufik hidayat vs lindan olimpiade london 2012 are grossly normal. Additionally, insomnia was related to decreased immune functioning.

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Identification and implementation of effective strategies to prevent and manage DM should be considered as a public health priority. Considering the urinary tract substitution effects on renal function and metabolism, particularly for the role of glucose on proximal and distal tubule the usefulness avix bird rain spray of administering only glucidic solutions and maintaining a good diuresis is underlined.

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This second-generation virus is deleted of E1 and contains a temperature-sensitive mutation in the E2a gene, which encodes a defective DNA-binding protein. Intrauterine growth restriction is associated with structural alterations in human umbilical cord and decreased nitric oxide-induced relaxation of umbilical vein. Several studies have demonstrated anomalous asymmetry of the 100-msec latency auditory-evoked field (M100) in schizophrenia. The German Cooperative Group on Radiotherapy in Benign Diseases (GCG-BD) conducted a pattern-of-care study (PCS) to analyze the radiation therapy (RT) practice for pigmented villonodular synovitis (PVNS). efavirenz prescribing information MODIFICATION OF ANAL CUP TECHNIQUE FOR SMALL EXPERIMENTAL ANIMALS.

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Urinary BPA concentrations deflegmin 7 5mg ml dawkowanie augmentin were not associated with adverse reproductive and pregnancy outcomes among women from a fertility clinic. In this double-blind, randomized, placebo-controlled, four-way, crossover study, we examined the effects of pioglitazone (45 mg/d for 6 wk) or placebo on renal calcium and phosphate excretion and PTH levels during different sodium intakes in 16 individuals (eight with type 2 diabetes and eight with essential hypertension). Social deprivation and rigidity in the performance of feebleminded children.

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Comparison of drug use and psychiatric morbidity between prostitute and non-prostitute female drug users in Glasgow, Scotland. The continuous changes in the dose of acyclovir in varicella zoster symptoms regulation of financing and reimbursement represent a big challenge for ophthalmology.

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However, the process itself did not destroy the oil nanodroplets, which could easily generic alfuzosin be redispersed when the powder was put back in contact with water. Precise staging of liver fibrosis is essential for patient management in clinical practice because the presence of bridging fibrosis represents a strong indication for antiviral therapy, while cirrhosis requires a specific follow-up. There is no randomized controlled trial evidence to support this schedule, and model-based analysis is required. Transitions in caregiving: evaluating a person-centered approach to supporting family caregivers in the community. Measuring skin cancer risk in African Americans: is the Fitzpatrick Skin Type Classification Scale culturally sensitive?

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Based on preclinical studies phosphodiesterase 4 (PDE4) inhibitors may exhibit beneficial anti-inflammatory and anti-remodeling properties for the treatment of these respiratory disorders. Cutaneous epithelioma of the sole of the foot with lamotrigina 25 mg tabletas lymphatic recurrence despite high amputation and inguinoc-rural adenectomy Analysis of the content of radioactive sodium labeled sodium chloride