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Telviran (Acyclovir)
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Acyclovir

Telviran is an antiviral drug, a synthetic nucleoside analogue, that has inhibitory activity (interferes with viral replication) against the herpes viruses, including herpes simplex 1 and 2 (cold sores and genital herpes), varicella-zoster (shingles and chickenpox), and Epstein-Barr virus (mononucleosis). Viruses take over living cells and reproduce themselves, often at the expense of the host cell. The Telviran is converted to an active form by the virus itself, and the virus then uses the active form of Telviran rather than the nucleoside it normally uses to manufacture DNA, a critical component of viral replication. Incorporation of active Telviran into new viral DNA stops the production of the DNA. Virally infected cells absorb more Telviran than normal cells and convert more of it to the active form, which prolongs its antiviral activity. The FDA approved Telviran in March 1982.

Other names for this medication:
Acyclovir, Abduce, Acic, Aciclobeta, Aciclomed, Aciclostad, Aciclovirum, Acifar, Acihexal, Aciklovir, Acitop, Acivir, Acivirex, Acivision, Acix, Actios, Activir, Acycloguanosine, Acyl, Acyrax, Acyvir, Aklovir, Antivir, Asiviral, Avir, Aviral, Avix, Avorax, Blistex, Cicloferon, Cicloviral, Clinovir, Clirbest, Clopes, Clovate, Clovir, Cusiviral, Cyclomed, Cyclovax, Cyclovex, Cyclovir, Danovir, Declovir, Epsin, Eurovir, Hascovir, Hernovir, Herperax, Herpesil, Herpesin, Herpex, Herpin, Herplex, Heviran, Immunovir, Lisovyr, Lovir, Lovire, Lovrak, Medovir, Menova, Ocuvir, Poviral, Ranvir, Remex, Rexan, Scanovir, Sitavig, Sophivir, Soviclor, Supraviran, Telviran, Uniplex, Vilerm, Viraban, Viralex, Viratac, Viratop, Virest, Virestat, Virex, Virless, Virolex, Viromed, Virosil, Virostatic, Virovir, Virucid, Viruderm, Virustat, Virux, Vivorax, Xiclovir, Xorox, Zevin, Ziverone, Zoral, Zorax, Zoraxin, Zovirax,

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The results suggest that the rostral portion of the primitive streak at HH stage 3 consists of at least two distinct subpopulations, entering either the cardiomyocyte lineage or the endocardial cell lineage. Expression levels of 4 biomarkers correlated with pCR after preCRT for rectal cancer. In most assays, the rpoE mutant was more severely affected than the degS mutant and a sigma(E)-dependent reporter gene was more active in the degS mutant than the rpoE strain. Accidents are the leading cause of death in children over the age of 1 year. Amino acid composition of the positive, neutral, and negative peptides of trypsin-digested Escherichia coli protein.

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Here, we used fMRI to investigate whether activity within primary auditory cortex (PAC) is sensitive to the perceived clarity of degraded sentences. The aim of antibiotic therapy is pathogen eradication, which is often assumed on the basis of the alleviation of the signs and symptoms of the disease. Based on different knockout lines, phenolic profiling, and immunohistochemistry, we present evidence that both enzymes fulfil distinct, yet different tasks in Arabidopsis anthers. Syringomyelia is a formation of fluid-filled cavities in the spinal cord, caused by a number of situations including trauma.

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Significant differences in the metrics for these regions were found in the early maps (1912, 1944), but these differences were not significant in 1973 or 1989. The CLA-dependent chemiluminescence by cord blood granulocytes was significantly higher than that by normal adult granulocytes. Socio-demographic, clinical and sick leave information was gathered.

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Diagnostic accuracy of computed tomography imaging of surgically treated acute acalculous cholecystitis in critically ill patients. Chemically induced unilateral renal disease was associated with a high incidence of proteinuria, diuresis, a morphological spectrum ranging from perinephritis to acute tubular or cortical necrosis, and unilateral or bilateral glomerular fibrinogen deposition during the first 2 wk after induction. Inhibition of dihydroorotate dehydrogenase by the immunosuppressive agent leflunomide.

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Production of 3-(1,2-epoxypropyl)-5,6-dihydro-5-hydroxy-6-methylpyran-2-one by Aspergillus ochraceus Wilhelm. Data from the 1996 Medical Expenditure Panel Survey were examined by means of logistic regression techniques.

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However, transient increases in ICP without changes in middle cerebral artery blood flow velocity may occur concomitant with decreases in MAP. Encephalitozoonosis in 2 South American Fur Seal (Arctocephalus australis) Pups. The independent and combined risks from the different categories of PG-BMI and GWG with IUGR and macrosomia were determined by means of relative risk (RR).

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Dye dilution curves have been used to calculate cardiac output under conditions of normal circulation. Techniques for suppressing amplified spontaneous emission are employed to favor the signal gain 23 nm off the gain peak of the Yb-doped fiber. Force dependent internalization of magnetic nanoparticles results in highly loaded endothelial cells for use as potential therapy delivery vectors.

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Memory deficit produced by bilateral lesions in the hippocampal zone. Mapping migratory bird prevalence using remote sensing data fusion. In certain patients, atrial fibrillation and flutter may be different expressions of the same electrical disease, and eradication of the flutter circuit will not prevent the eventual manifestation of atrial fibrillation.

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Unusual evolution of ciprofloxacin-induced hepatitis revealing a possible link with IgG4-associated autoimmune hepatitis. Furthermore, this work describes why the neuronal correlates of key cognitive concepts, such as learning and memory, are so deeply connected with mechanisms implicated in the development and maintenance of addictive behaviour so that modification of these systems may inevitably run the risk of addiction to the enhancing drugs. The combination of selective staining and 3D reconstruction provides a valuable tool for revealing aspects of synaptic morphology not apparent from standard electron microscopic evaluation.

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In the pursuit of CBCT-based treatment adaptation, dedicated imaging protocols may be required. For the best PLSR model performance, the correlation coefficient of validation set increased to 0.926 and the root of mean square errors for validation set to 0.045 in the optimization interval PLSR model. In this paper, we argue that one important reason for this failure is that the solutions proposed do not adequately address the societal concerns that motivated the original research.

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However, the E3 ligase that targets hSSB1 for destruction is still unknown. IL-1beta induces eotaxin gene transcription in A549 airway epithelial cells through NF-kappaB. Phenotypic reversions at the W/Kit locus mediated by mitotic recombination in mice. This paper examines 35 patients whose persistent swelling of the parotid was diagnosed as sialosis, and shows that diabetes mellitus and alcoholism are the most common causes.

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Whereas the neurofibroma series probably arise from a mesenchymal origin closer to a fibroblast. An institution-wide training programme for HIV care physicians in smoking cessation counselling led to increased smoking cessation and fewer relapses. INCORPORATION OF C-14-LABELED CO2 INTO GLYCOALKALOIDS IN THE LEAVES OF SOLANUM AVICULARE Erythrodermic psoriasis is a severe manifestation of psoriasis and can be triggered by several factors.

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Obesity is related to the development of vascular diseases and metabolic complications. The autosomal dominant prealbumin amyloidoses are late-onset disorders characterized by varying degrees of peripheral neuropathy, nephropathy and cardiomyopathy.

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We find that epistatic interactions between the determinants of the expression of a gene and its downstream effect impose significant constraints on evolution, but these interactions do allow the gradual evolution of increased robustness. Drop spreading on heterogeneous substrates via Monte Carlo simulations. This is partly due to our poor understanding of the phosphatase-substrate network. Thus, pp93 and pp95/96 may be important GH signal transducers independent of PKC activation and different from the characterized members in the JAK-STAT pathway. Comprehensibility of latent muscle participation in lupus erythematodes

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Among them, the peaks 1, 3, 4, 5, 8, 9, 10, 12, 13, and 16 were identified 3,4-dihodroxybenzoic acid, 4-Hydroxybenzoic Acid, epicatechin, puerarin, daidzein, liquiritigenin, calycosin, genistein, formononetin, and prunetin, respectively. The Oregon Pregnancy Risk Assessment Monitoring System (PRAMS) is a population-based survey of postpartum women.

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We assessed the potential for increasing the specificity for CAH by use of a second step involving analysis of the CYP21 gene. We conducted a comprehensive literature search of MEDLINE, PsychINFO and Web of Science databases up to May 2009, supplemented by a search of the references of all relevant articles. The characteristic time for this process closely matches the lifetimes of the 7AB excited state. Roentgenographic evidence of bone and soft tissue abnormalities may be noted in the upper extremities of diabetics. Accurate prediction is essential for patient counselling, appropriate selection of treatments and determination of eligibility for clinical trials.

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UDP-N-acetylglucosamine:dolichyl-phosphate N-acetylglucosamine-1-phosphate transferase is amplified in tunicamycin-resistant soybean cells. Natural history of tumour-related sacral obliteration with nerve-root preservation. The objective of this study was to replicate this association in a sample of U.S. Colonoscopic examination revealed aphthous ulcers in the right colon, and mucosal biopsy culture grew Yersinia pseudotuberculosis. On the extremities it affects the distal portion more than the proximal areas.

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Cytochrome P450 catalyzes monooxidation reactions of many organic compounds in the presence of hydroperoxides even in the absence of electron-transfer proteins and molecular oxygen. Ultrasound-guided core needle biopsy of breast masses: How many cores are necessary to diagnose cancer?

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ELEVATED URINARY LDH AND ALKALINE PHOSPHATASE ACTIVITIES FOR THE DIAGNOSIS OF RENAL ADENOCARCINOMAS. It stresses the necessity of cooperation across disciplines and the combination of space and ground based investigations.

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The torpedine electric fish Narcine brasiliensis has two morphologically distinct electric organs (main and accessory) which also differ with respect to a number of electrophysiological properties. Is atherosclerosis in diabetes and impaired fasting glucose driven by elevated LDL cholesterol or by decreased HDL cholesterol? The involvement of an insurance company in new forms of health care delivery. Most fertile donors presented low values for ssDNA and dsDNA fragmentation (low-equivalent Comet profile), which would be the best prognosis for achieving a pregnancy.

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Major advances in understanding the role of vitamin A in vertebrate heart formation have been made since the discovery that the vitamin A active form, all-trans-retinoic acid, regulates many genes, including developmental genes. This reveals that the organization of PS II complexes is different in the wild type and both mutants indicating altered connection between the LHC II and the RC core complexes of PS II in both mutants. The aim of this study was to assess the impact of hypertrophied tonsils on velopharyngeal function in children with repaired cleft palate and to measure the effect of tonsillectomy on velopharyngeal closure and speech resonance. Definitions of DSM-III, DSM-IV-TR, and International Classification of Diseases. Demyelinated areas improved after immunomodulatory therapy, but cortical lesions spread in both hemispheres.

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The purpose of this study was to develop a DPT that could serve as an ophthalmic delivery vehicle for gatifloxacin and to evaluate its in vitro and in vivo delivery after topical application. Iron intakes of premenopausal women were less than two-thirds RDA.

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Understanding how stigmatized identities contribute to increased rates of depression and anxiety is critical to stigma reduction and mental health treatment. Lymphocytes primed with xenogenized LCLs and challenged with unmodified LCLs showed increased IFNgamma secretion compared with lymphocytes primed with non-xenogenized LCLs. Relief of presenting symptoms is to be expected, and long-term results suggest that the operation is durable.

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All seven surviving fetuses had growth retardation at delivery and four also showed severe malformations. Stomatal and pavement cell density linked to leaf internal CO2 concentration. Veratrum viride and hexamethonium in the treatment of severe diastolic hypertension. Comparative studies on enzyme activities in the mucosa of corpus and endocervix uteri under various hormonal conditions. What is the relationship between myocardial perfusion imaging and coronary artery disease risk factors and markers of inflammation?

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At 6 months, the fourth pattern was characterized predominantly by breastfeeding and at 15 months, by contemporary-style foods including herbs, legumes, nuts, raw fruit and vegetables. (ii) Transfection of Chinese hamster ovary cells with an expression plasmid containing the mutant M1 cDNA resulted in the production of dATP feedback-resistant ribonucleotide reductase. Regulation of muscle differentiation: stimulation of myoblast fusion in vitro by catecholamines. Spectroscopic and structural characterization of these compounds supports the idea that electrons are stored in the ligand framework and used in subsequent reactivity.

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PRESENCE OF AN ALBUMIN AS A NORMAL CONSTITUENT OF THYROID PROTEINS Isolation of feather keratin mRNA and its translation in a rabbit reticulocyte cell-free system. The benefits of physical exercise on a regular basis over endothelial function have been demonstrated in experiments with animals and humans.

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Electrochemical studies on various metallic dental restoration materials. In this paper, we explain how the activation of Cdc20 (which causes the activation of separase and a decrease of Cdk1 kinase activity) provides an initial trigger for the activation of the MEN-Cdc14 positive feedback loops, which in turn, flips the second irreversible Cdk-APC(Cdh1) switch on the APC(Cdh1) side).

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The xylXYZ genes encode three subunits of toluate 1,2-dioxygenase. A pyrene-excimer-forming probe allowed the easy and sensitive detection of a single base mismatch in target DNA. We recently demonstrated that papillary microcarcinomas with preoperatively detectable node metastasis in the lateral compartment on ultrasonography (clinically apparent metastasis) show worse postoperative relapse-free survival than those with no metastasis or metastasis that could not be detected preoperatively, but was confirmed by pathological examination after surgery (occult metastasis).

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coli K12 carrying a missense mutation or deletion in the dnaK, dnaJ, or grpE gene were virtually unable to be transformed by mini-F DNA at the temperature (30 degrees C) that permits cell growth. Some patients also experience neutrophilic infiltrates in other organs, defining the neutrophilic disease. Distribution and organoleptic impact of ethyl 2-methylbutanoate enantiomers in wine.

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Unlike wild type gammaB, the gammaB-I4F mutant protein binds to alpha-crystallin to form high molecular weight complexes in vivo and in vitro. New effects of polarization multistability and polarization hysteresis in a coherently driven polariton system in a semiconductor microcavity are predicted and theoretically analyzed. To describe institutional variation in traumatic brain injury (TBI) inpatient rehabilitation program characteristics and evaluate to what extent patient factors and center effects explain how TBI inpatient rehabilitation services are delivered. We propose that the nonselective depression of transmission from group I and II afferents at short intervals is due to the activation of reticulospinal pathways by cells or fibers stimulated within the cuneiform area. Using Monte Carlo simulation to determine optimal dosing regimen for cefetamet sodium for injection.

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Stimulation of choline acetyl transferase activity by l- and d-carnitine in brain areas of neonate rats. Investigation of the possibility of copper recovery from the flotation tailings by acid leaching. The developmental course of salivary alpha-amylase and cortisol from 12 to 36 months: Relations with early poverty and later behavior problems. Results of the macrophage migration test during the early phase of Rauscher leukemia

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A population-based sample of 11 525 men 40 years or older (248,217,013 weighted men) in the United States, selected from the Medical Expenditure Panel Survey (2003-2006). The mutation status of the KRAS gene is likely involved in mTOR pathway and to be a prognosis marker for colorectal cancer in kidney transplantation. Recent advances in plasmepsin medicinal chemistry and implications for future antimalarial drug discovery efforts. Bilateral intrastriatal injections of quinolinic acid (QA) (180 nmoles) induced weight loss and neurologic and behavioral deficits including convulsions, decreased catalepsy response to haloperidol, increased nocturnal locomotor activity, and abnormal feeding behavior in adult male Sprague-Dawley rats.

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