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Topimax (Topiramate)

Topimax is a broad spectrum, antiepileptic drug used for various types of seizures, Lennox-Gastaut syndrome (a type of childhood onset epilepsy), and migraine prophylaxis. Topimax blocks voltage-dependent sodium channels, potentiates gamma-aminobutyric acid (GABA) activity at some of the GABA receptors, and inhibits potentiation of the glutamate receptor and carbonic anhydrase enzyme, which all contribute to its antiepileptic and antimigraine efficacy.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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Development of pregnancy in cases of criminal abortion with special references to older primigravidae Osteoporosis-related fractures are a major public health problem and one in two women and one in four men are affected with osteoporosis-related fractures. A systematic review of information and communication technology-based interventions for promoting physical activity behavior change in children and adolescents. One hundred sixty obese adolescents and 40 control subjects were enrolled in the study. What are the aspects of successful leadership in implementing such a practice change, and how can those behaviors be transferred to other leaders?

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A widely accepted yet occasionally contested measure of FE in dairy cattle is residual feed intake (RFI). Changes in blood coagulation properties in acute cranio-cerebral trauma Less attention has been paid to the development of personality, its phenotypic plasticity, and the influence of manipulation of early environmental factors. Evolution of nutrient structure and phytoplankton composition in the Jiaozhou Bay ecosystem. Therefore, emergency contraception and prophylaxis for sexually transmitted diseases should be available and provided to these women.

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Canrenoate reversal of inhibitory effects of digoxin on basal and furosemide-stimulated renin secretion. Highest overall satisfaction was seen related to nurse practitioner and registered nurse behaviors and lowest satisfaction to operational aspects. The nuclear quadrupole resonance (NQR) method has been applied to Heroin Base (HB) to find an optimised multi-pulse technique for effective detection of HB. An experience with repeated examinations of 656 patients operated upon for bile calculi is presented. Preliminary observations using a multi-layer ELISA method for the detection of Entamoeba histolytica trophozoite antigens in stool samples.

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Dysphagia persisted despite resolution of candidiasis, for which we successfully performed endoscopic balloon dilatation of the stricture. Treatment of this lesion requires the same preparation as for any other site of pheochromocytoma. Cold water cleaning of brain proteins, biofilm and bone - harnessing an ultrasonically activated stream. However, no response to the appropriate therapy for this disease was observed. IL-8 -251 A/T polymorphism is associated with ACS risk in the Chinese Han population and the A allele of IL-8 -251 A/T may be an independent predictive factor for ACS.

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Nodules with moderate to high cellularity, nuclear atypia, and frequent mitotic figures (42 per 50 high-power fields) were noted. A diffusion coefficient of 4.13x10(-8) cm2 s(-1) was found for nandrolone using chronoamperometry. On the other hand, the control group (no treatment) had significantly lower micro-shear bond strength than all the other groups. The present study examines the presence and impact of grief-related panic symptoms in CG.

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Modifications in repair and expression of potentially lethal damage (alpha-PLD) as measured by delayed plating or treatment with beta-araA in plateau-phase Ehrlich ascites tumor cells after exposure to charged particles of various specific energies. PD is associated with increased rates of infection, dislocation, revision shoulder arthroplasty, fracture, component loosening, and systemic complications after conventional TSA, RSA, and shoulder HA. Specific features of the clinical picture and difficulties of diagnostics of laryngeal paresis and paralysis in the newborn babies, during breast feeding and early infancy Elevated serum level of vitamin D or its metabolites was linked to the pathogenesis of hypercalcemia in these disorders. Cloning and characterization of myogenin from seabream (Sparus aurata) and analysis of promoter muscle specificity.

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Morphological changes of mucosa are the cause of voice quality disorders - dysphonia. In patients who were tumor free after treatment for oral cancer, higher antibody titers to HSV-1 were associated with longer survival times. Simultaneous determination of five nucleosides and nucleobases of Rehmannia glutinosa Libosch. Until now, some important problems of cell physiology have been difficult to investigate due to interactions between probes and cells, excretion of probes from cells and the inability to make in situ observations deep within the cell, within tissues and structures. The diagnosis of dislocation of the hip in newborns and the primary results of immediate treatment.

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Acyclovir was reported to decrease the sensitivity to aspirin in some AIA patients. Many treatment modalities have been developed over the years for the management of atrial fibrillation (AF).

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Enterococci are the third most common nosocomial bloodstream pathogen and frequently are the causative pathogen(s) of intra-abdominal, genitourinary, surgical wound, endovascular, or other serious infections. We conclude that the mitochondrial genome has been maintained to ensure the correct localization of highly hydrophobic membrane proteins. We aimed to review the literature of the inhibitor of differentiation-3 (ID3) gene in relation to adipose tissue and angiogenesis in humans in order to determine whether ID3 could be involved in the regulation of adipose tissue expansion and metabolic health in human obesity.

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Morphological changes shown by transmission electron microscopy were used as ultrastructural markers to confirm the findings made by scanning electron microscopy relating to the various phases of the cell cycle. RIF was administered as a single 600-mg dose to 24 healthy volunteers and 24 TB patients, followed by serial blood sampling. Although resynchronization therapy improves this correlation, the changes in electrical activation may not yield similar changes in left ventricular mechanics particularly depending on the underlying myocardial substrate.

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The primary method used in the initial diagnosis, monitoring of response, and determination of progression in neuro-oncology is neuroimaging techniques such as magnetic resonance imaging. The three Escherichia coli cultures were stimulatory, but most other Escherichia cultures were inhibitory. A method for transforming some strains of Bacteroides has been developed.

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Genome-Wide Identification of MESP1 Targets Demonstrates Primary Regulation Over Mesendoderm Gene Activity. Current challenges include the optimization of drug administration, the identification of potential biomarkers of tumor sensitivity, and combination studies with cytotoxic drugs. Determination of the amount of homology required for recombination in bacteriophage T4.

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Here, we report an unusual case of extensive DSM that showed good clinical and angiographic results after endovascular embolization. Past, Present and Future of Antiepileptic Drug Therapy - Finding a Place for Heterocyclics.

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Adenovirus targeting to HLA-A1/MAGE-A1-positive tumor cells by fusing a single-chain T-cell receptor with minor capsid protein IX. Time-dependent covariates in the Cox proportional hazards model.

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Hypoxia- and H/R-treated BBB endothelium showed increased HIF1alpha protein expression in both cytoplasmic and nuclear fractions, in ex vivo and in vitro models. The percentage of more advanced cancers, larger in size and less differentiated, was higher after the accident, when the pool of neglected cancers was diagnosed due to the screening and improved diagnostics. The majority of babesiosis infections, however, are subclinical. In 6 patients (mean age approximately 66.3 years, 4 males, 2 females) with a risky location of a colorectal metastasis (liver segment III or VI), the targeted air instillation was performed between the liver and stomach (4 / 6) and colon (2 / 6). Direct observation of the phase behavior of the lipid bilayers of phage PM2 and the intact host cells by 1H-31P cross-polarization NMR.

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Neuromuscular and ganglionic effects of the bis-choline ester of adipic acid Intense exercise causing central retinal vein occlusion in a young patient: case report and review of the literature. Constituents of the Vietnamese medicinal plant Orthosiphon stamineus. The sizes of these nanocrystals could be tuned as a function of pH, and larger semiconductor nanocrystals were grown as the pH of growth solutions was increased. Timing of surgery for feminizing genitoplasty in patients suffering from congenital adrenal hyperplasia.

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coli cells as functional proteins, and their properties were characterized in detail. To potentiate the effect of basic therapy and to correct of immune dysfunction in type 2 diabetes mellitus (T2DM) patients with diabetic foot syndrome by using the immunoregulatory peptide imunofan. Conventional immunosuppressive therapy has been widely used in patients with progressive renal involvement or relapsing disease. For the first time, we identified differences in brain volumes in the olfactory gyrus.

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Chemical composition of lactosiderophilin (lactotransferin) isolated from human milk The corresponding recommendations were made following the GRADE (Grading of Recommendations, Assessment, Development, and Evaluation) approach. Exocrine pancreatic insufficiency: a new recessive mutation in mice.

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Since AH III can be considered as a precursor of endometrial cancer, LIF could be a marker of cell transformation. Several questions remain open, for instance, why the response to bromocriptine is unpredictable, and whether prolonged therapy with a dopaminergic drug whose effect is not restrained to hypophyseal cells will have adverse side-effects. The reaction of solidification of the serum of myelomatous patients by urethane Possibility of Fisher renormalization of the critical exponents in an Ising fluid. The enzyme, which in untreated cells is present in the cytoplasm, except for the organelles, and in the nucleoplasm, after IGF-I treatment is reduced in the cytoplasm and almost doubled in the nucleus.

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Intrinsic defect in B cells of patients with hyper-immunoglobulin M syndrome. Physical therapists (PTs) serve as physician extenders performing direct access evaluations for musculoskeletal conditions.

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An adult B-cell precursor acute lymphoblastic leukemia with multiple secondary cytogenetic aberrations. Springs were then incorporated in the distraction rods so as to allow direct readings of the distraction forces, and a total force of 18 kilograms was not exceeded in the last fifty-six patients. Contextual influences of emotional speech prosody on face processing: how much is enough? Slight metabolic improvements were seen, in particular with RO-151 high dose, however, the observed changes often did not reach statistical significance and were not clearly dose dependent.

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Di- and triphosphopyridine nucleotide isocitric dehydrogenases in yeast. Coronary artery bypass grafting using a bifurcating radial artery. This complication may be unique to children, in whom the bone is malleable. Biodistribution of Technetium-99m pertechnetate after total gastrectomy and Roux-en-Y jejunal pouch.

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As reviewed here, it is important in clinical dentistry to understand the distinctive features of the bones of the jaw. Animals fed a diet with high dietary phosphate and improper calcium to phosphorus ratio showed severe nephrocalcinosis. ROS increase vascular tone by influencing the regulatory role of endothelium and by direct effects on the contractility of vascular smooth muscle.

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MD simulations emerged as a powerful and popular tool to study dynamic behavior of proteins and macromolecule complexes at the atomic resolution. In addition, the T-antigen-associated protein kinase can use GTP and ATP as phosphate donors. Precise and accurate dose delivery is critically important in external beam radiation therapy.

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REDUCTION BY CHLORPROMAZINE OF PYLORUS-LIGATION ULCERS IN THE RAT. Each patient was matched for age, sex, year of operation, and number of preoperative transfusions with control patients with sickle cell disease who had open cholecystectomy. Biochemical identification of bovine spongiform encephalopathies in cattle. Unlike other Afa/Dr DAEC strains, EC7372 expresses a functional hemolysin that promotes a rapid cellular lysis.

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A total of 178 patients younger than 21 years who underwent kidney transplantation with daclizumab induction between 1997 and 2006. The fibrin binding study of treated t-PA revealed substantial loss of binding to CNBr-digested fibrinogen (FDP-CNBr). Intracellular delivery of biologically active proteins remains a formidable challenge in biomedical research. Intra-oral radiographs including a reference material perform well as a densitometric tool.

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The clinical features of a 9-year-old boy with an extra-adrenal phaeochromocytoma, complicated by malignant hypertension, are described. Protein folding appears to be intact because mutant enzymes express to similar levels in Sf9 cells and addition of peptides representing the C-terminal amino acids, including the simple hexamer PMEVWT, restores partial activity to several of the mutants. The device consists of a p-i-n diode structure that incorporates a coupled double quantum dot. Neurofibrillary tangles were not seen in the primary motor cortex, which appeared histologically unremarkable. Molluscan AK genes typically have a highly conserved six-exon/five-intron organization, a structure that is very similar to that of the platyhelminth Schistosoma mansoni Arthropod and nematode AK genes have fewer introns, while the cnidarian and protozoan genes each display unique exon/intron organization when compared to the other AK genes.

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On the effects of the paratumoral and intramuscular injection of an organ extract which increase cell respiration on the mousre sarcoma S 180 during radiotherapy A coated shearing plate interferometer was used in transmission to produce sharp multiple-beam fringes that rotate as the collimation of the incoming wave front from the lens under test changes. An alteration in the interconversion equilibrium between phosphoinositides which is directed towards polyphosphoinositide formation may lead to altered membrane ionic fluxes. Inflammation and thrombosis are closely related processes, which may play a role in the pathogenesis, as well as complications, of inflammatory bowel disease (IBD).

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To our knowledge, pBLIC is the first LIC vector for retroviral transduction-mediated stable gene expression in mammalian cells. A total of 19 reports published from different regions of Iran from March 1999-May 2013 were included in this study. Primary biliary cirrhosis induced by interferon-alpha therapy for hepatitis C virus infection.

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The pineal gland: a comparative MR imaging study in children and adults with respect to normal anatomical variations and pineal cysts. Increasing Use of Neoadjuvant Treatment for T1 and T2 HER2-Positive Tumors. Development and validation of a Spanish version of the Athletic Coping Skills Inventory, ACSI-28. Intramammary lymphoscintigraphy can be used to define the lymphatic drainage patterns of individual breast cancers.

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IS insertions, which relieved this inhibitory effect and thereby provided a selective advantage, were found exclusively in plasmids carrying the cloned DNA in only one of the two orientations. Analysis of the effects of proteins oxidized in vitro on human endothelial cell (EC) viability was also performed.

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CJ 012,255 (CJ), a SP antagonist that binds to NK-1R, was injected into lean, diet-induced obese (DIO), and genetically obese (ob/ob) mice, and its effects on body weight, adiposity, and insulin sensitivity were investigated. The efficacy of zoledronic acid (ZOL), with or without the anticancer drug ifosfamide (IFO), was tested on primary bone tumor growth using a rat-transplantable model of osteosarcoma. NdFeB permanent magnets (PMs) are widely used in high performance electrical machines, but their relatively high conductivity subjects them to eddy current losses that can lead to magnetization loss. In the test condition, learned words and corresponding prototypes were presented along with non-associated new words, and participants were asked to indicate which of the words they recognized.

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Etiology of acquired spinal arteriovenous fistula has been reported. Activation of macrophages by LPS was associated with enhanced expression of immune response and metabolic proteins.

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coli single-stranded DNA-binding protein with single-stranded poly-(2-thiouridylic acid). Cross-cultural analysis of eventfulness in the lives of people with schizophrenia. These changes were contrary to anxiogenic effect of the CCK-4 and demonstrated an anxiolytic effect of the immunisation. The identifying marks extend into the item and cannot be readily removed as surface stampings.

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Results of a consecutive study series from the surgical viewpoint The induction of donor T-cell anergy to recipient cells for reducing GVHD could be one way of expanding donor candidates for HLA-mismatched hematopoietic SCT.

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Influenza A virus-induced degradation of eukaryotic translation initiation factor 4B contributes to viral replication by suppressing IFITM3 protein expression. Initial experiences with CO2 as a gaseous contrast medium in digital subtraction angiography No statistically significant differences in accuracy were found between rhodogil 750.000 u.i./125 mg ECAP, EABR, or matched current levels or between the basal and apical electrode in approximations of equal loudness. Cells were isolated from the DCIS excision and transfected with a plasmid expressing hTERT, a catalytic subunit of telomerase. The tumor lysis syndrome occurs most often in patients with large tumor burdens that are very sensitive to chemotherapy and radiotherapy, such as acute or chronic leukaemias with high leukocyte counts and high-grade lymphoma.

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Stability of the properties of luminescent bacteria stored for a long time on vaseline oil An evaluation of the underlying erythromycin ophthalmic ointment how long to use mechanisms of bloodstain pattern analysis error.

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A mutant cell line was selected from wild type S49 lymphoblasts that expressed a novel high affinity purine base transport system not found in parental cells or any other mammalian cell line (Aronow, B., Toll, D., Patrick, J., Hollingsworth, P., McCartan, K., and Ullman, B. The loss of muscle mass with age, also known as sarcopenia, is a major scientific and public health problem. Furthermore, OVX had a more rapid impact on mRNA levels in mature animals than in skeletally immature animals. Through defined cut-off values, SI, SSI and SAP values are differentiated in normal and abnormal, whereas abnormal values point towards gastroesophageal reflux (GER) as the origin emeproton 20 mg precious accents of symptoms.

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Despite these recent advances, many aspects of oroken 200mg side effects progestin signaling through these two families of novel membrane proteins remain unresolved. Due to uncertainties regarding the preoperative diagnosis, the patient underwent bilio-enteric bypass with an intraoperative pancreatic and bile duct biopsy.

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Difficulties in the treatment of skin disease occasioned by extraordinary times For proven pulmonary metastases, the level of evidence for a curative approach is low, but some patients might benefit from a pantodac drugs metastasectomy followed by an elective and appropriate complementary oncological treatment. When GLBTQ youth of color are living in poor neighborhoods or suffer from some form of racial discrimination, they face even greater challenges. The measurement of blood-plasma velocity distributions with spatial and temporal resolution in vivo is inevitable for the determination of shear stress distributions in complex geometries at unsteady flow conditions like in the beating heart. The measured absorbance spectra are processed by multivariate analyses.

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The only abilities that he conserved in similar conditions to those prior to his acute disease were his capacity to swim (including the style of jumping into the water), bike riding, playing football, dominoes, cards, etc., which he had learned during his childhood, to say the numbers and the alphabet letters rapidly by heart (without knowing them) and to avoid cars on the street. Patients may be asymptomatic or their condition may give rise to undifferentiated fever, dengue fever, dengue haemorrhagic fever (DHF), or dengue shock syndrome. The effects of dopamine and its agonists on transmission from muscle afferents to spinal neurones were investigated in the cat and guinea-pig spinal cord, by measuring the drug effects on the amplitude of monosynaptic field potentials levothroid classification of organisms evoked by electrical stimulation of group I and group II muscle afferents.

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These data are interpreted to mean that the reagents increase the time acetylcholine is bound to the receptor before the channel opens and is most probably due to a change in receptor affinity brought about by chemical modification of the receptor protein. As a result of this treatment, facial growth retardation and oral abnormalities such as malformation of teeth tamsulosina tabs plm and microstomia can cause esthetic and functional problems. Ayurvedic system of medicine is well known for treating renal problems. Iron and vitamin B-12 metabolism in patients following partial gastrectomy for peptic ulcer Immediate surgical treatment of all acute type A dissections with resection of the intimal tear and use of hypothermic circulatory arrest for distal anastomosis results in acceptable early mortality rates and excellent long-term survival.

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The initial findings of perimetry included an enlarged blind spot tacrolimus side effects tinnitus causes of Mariotte, depression of the central field, and paracentral scotoma. Contribution to the kinetic study of the radiolysis of metal-organic complexes Myocardial scintigraphy with 99m-Tc-pyrophosphate in patients with acute myocardial infarction. In particular, we focus on the transcription factors that initiate these cascades.

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Polypharmacy in patients hospitalised for acute exacerbation of COPD. Induction of infertility in female rats after active immunization with 24 kD antigens from rat testes. Fenofibrate and dipyridamole treatments in low-doses either alone or in combination blunted zocef 250 in pregnancy the development of nephropathy in diabetic rats.