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Topina (Topiramate)
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Topiramate

Topina is a medication used to treat epilepsy and prevent migraines. It has also been used in alcohol dependence. For epilepsy this includes treatment for generalized or focal seizures. It is taken by mouth. Topina is also used with other medications to control seizures in people who have Lennox-Gastaut syndrome (a disorder that causes seizures and developmental delays). Topina is also used to prevent migraine headaches but not to relieve the pain of migraine headaches when they occur.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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This is followed by activation of secretory pathways to release preformed and newly generated mediators of bronchoconstriction and vascular permeability. If somebody ascends from sea level to higher altitude within a short time, the change of the atmospheric conditions can be a danger for his life. Further characterization, using fluorescence-based thermal denaturation and a crystal structure of the isolated RNase H domain reveals that this compound can also bind the RNase H site and retains the metal-dependent binding mode of this class of molecules. To contrast impairments in reach-to-grasp coordination, in response to object location perturbation, in patients with right parietal and cerebellar lesions, in order to further elucidate the role of each area in reach-to-grasp coordination. (2) Does local delivery of D-AAs from low-viscosity bone grafts inhibit new bone formation in a large-animal model?

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The interactions between nanoparticles and vesicles are of significant interest both from a fundamental as well as from a practical point of view, as vesicles can serve as a model system for cell membranes. Extracted classes were described in terms of a number of known lifetime risk factors, and linked to the risk of undiagnosed angina (Rose questionnaire) at age 53 years.

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Human amniotic fluid stem cells (hAFSC) were cultured for 10 days in porcine follicle fluid (pFF) that was extracted from the medium follicle with high levels of hormones and Bmp 15 protein. Since previous works suggest that alterations of UL34 gene product result in a drastic impairment of primary envelopment of HSV-1 and trapping of capsids in the nucleus, the presented data may lead to the development of novel anti-herpetic therapeutic strategies where analogs of phosphoinositides are administered. BACKGROUND: Female athletes have a 4- to 6-fold increased risk for ACL injury compared with their male counterparts playing at similar levels in the same sports.

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In contrast, the high concentrations of Se presented neurotoxic to neurons, decreased the SelW mRNA levels and reduced the mRNA half-life of neuronal cells. Further studies on possible genetic modulators or genetic epistasis contributing to PSP and CBS development are warranted. It seems advisable in the case of women with dense breast tissue grade III and IV, women under the age of 50 and high-risk women. The proliferative cell nuclear antigen (PCNA), TBil and ALT of serum were detected, and the pathological changes of liver cell were observed. More than 2,000 parent-teenager dyads were interviewed by telephone, parents at permit and licensure and teenagers at permit, licensure, and 3, 6, and 12 months after licensure.

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This study is limited to the context of randomized clinical trials. A RELATIONSHIP BETWEEN THYROID FUNCTION AND A NATURALLY OCCURRING INHIBITOR OF HYPOPHYSIAL PROTEINASES. Relationships of concentrations of certain blood constituents with milk yield and age of cows in dairy herds. Patch-clamping or microelectrode arrays (MEA) are conventional methods to monitor the electrical activity in biological neural networks in vitro.

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The rate of return to the pre-fracture living situation in subjects of this age treated with hGH was significantly increased when compared with the placebo-treated group. Short-chain carbohydrates that are poorly absorbed exert osmotic effects in the intestinal lumen increasing its water volume, and are rapidly fermented by bacteria with consequent gas production. Reactions to gamma rays in rats with demedullated adrenal glands However, the results are consistent with previous studies that included a comparator group, had a longer duration of treatment, and included larger patient numbers. This study was aimed to determine the prevalence of these damages in patients with anterior recurrent shoulder dislocation.

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Our catalogue and classification of TCS may guide further studies into the role of TCS in GBS pathogenicity and biology. The mechanisms of hypercalcaemia in acute adrenal insufficiency are discussed.

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When comparing a young and an old cohort, there was a significant difference in performance. We review here several recent studies aimed at understanding the neural processes in premotor cortex that precede arm movements and lead to the initiation of movement. This optimal estimate of volatility is reflected in the fMRI signal in the anterior cingulate cortex (ACC) when each trial outcome is observed.

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It is shown that these sequences, which are almost identical locally, can have very different global patterns of physical properties. Mobilizing homeless youth for HIV prevention: a social network analysis of the acceptability of a face-to-face and online social networking intervention.

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The health effects associated with arsenic are numerous and the association between arsenic exposure and human disease has intensified the search for molecular mechanisms that describe the biological activity of arsenic in humans and leads to the aforementioned disease states. What are the mechanisms behind disuse and age-related skeletal muscle atrophy? Sixty-four patients (12 females, 52 males - mean age: 28.3) with a total of 75 fractures (54 LSCF, 21 HSCF) were included in the study. Recruitment of all major leukocyte subsets (neutrophils, monocytes, and lymphocytes) was reduced in Lam4(-/-) mice compared with WT. Receipt of AET is relatively low in the group of women most likely to benefit from its use, namely ER-positive patients who underwent BCS.

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Sixty-one of the remaining 371 were rejected because of inadequate histology or uncertainty as to exact site of origin. Temperature influences the level of glyphosate resistance in barnyardgrass (Echinochloa colona).

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Unlike the equilibrium Casimir force, the force amplitude is nonuniversal and explicitly depends on dynamics. These findings model the requirement in intact organisms for highly differentiated neurones to be specially protected against thermal stress. This provides a straightforward criterium for material selection. Physiological and ultrastructural features of human induced pluripotent and embryonic stem cell-derived skeletal myocytes in vitro. Dynamogenic effect stimulus intensity unconfounded by differential densities of reinforcement.

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Ciliated hepatic foregut cyst discovered after kidney transplantation in a hepatitis C virus-infected patient: a report of one case and review of the literature. Through alpha6-integrin internalization, sunburns might alter the interaction between melanocytes and the BM, resulting in apoptosis induced by loss of anchorage (anoikis). We included randomised controlled trials or cluster randomised trials that compared mechanical chest compression (using any device) with manual chest compression for adult patients following out-of-hospital cardiac arrest. Matrix metalloproteinase 9 (MMP-9) has been shown to be a potential biomarker for outcome prediction after neuron damage. Despite the absence of confirmed effects in humans, vaccines are frequently suspected of having adverse side-effects on the development of children.

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Effects of 5 daily injections of the neurotensin-mimetic NT69L on the expression of neurotensin receptors in rat brain. Serum and plasma samples were collected just before the dialysis session at baseline and 3 months. Inflammatory processes, such as phagocytosis, coagulation, and vascular dilation, promote the release of serine proteases by neutrophils, macrophages, mast cells, lymphocytes, and the epithelial or endothelial cells. CLINICO-HISTOLOGICAL COMPARISONS IN CHRONIC GASTRITIS AND FUNCTIONAL DISORDERS OF THE STOMACH

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ON ADVANTAGES OF EARLY TRAINING OF CONDITIONED INHIBITION IN PUPPIES As an illustration this article focuses on a Malaysian-Danish project and describes the implementation of CDM in Malaysia and refers to this specific project.

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Further historical studies in lesser studied regions of Latin America, Africa, and Asia are warranted for a full understanding of the global impact of the 1918 pandemic virus. The adults with congenital heart disease coped as well as adults without congenital heart disease. However, it is not clear to what extent such pre-existing cellular immunity can provide cross-subtype protection against novel emerging influenza A viruses. Mutations at Arg-73 and Arg-76, but not Lys-79, prevented pro-BNP processing. Tissue plasminogen activator and plasminogen activator inhibitor 1 in obese and lean patients with polycystic ovary syndrome.

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Conversely, genetically regulated behavioral modification could also lead secondarily to opiate changes. Identification of noncanonical melanoma-associated T cell epitopes for cancer immunotherapy. Modifications in blood and thyroid function in electroshock therapy experimental and critical observations Most surgeons favour the use of a mesh for open inguinal hernia repair as it has a low recurrence rate. Morphological changes of Fusarium oxysporum induced by CF66I, an antifungal compound from Burkholderia cepacia.

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Chi-square and a power analysis were used to compare these smears with results of smears from women older than 35 years of age with tissue diagnoses other than hyperplasia or carcinoma. Construction of a partial rabbit spleen cDNA library and identification of immunoglobulin clones. Workload affected how younger adults complied with automation, particularly with regard to detecting automation false alarms. The hyperosmotic conditions were shown to cause the destruction of the erythrocyte membrane skeleton, except for the cytoplasmic and membrane domains of band 3 proteins.

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In the present study, we determined the molecular regulation of constitutive IL-8 expression in human pancreatic cancer cells. The present report describes a child with ATR-X syndrome who suffered from periodical episodes of refractory vomiting.

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EEG AND BEHAVIORAL STUDY OF ALTERNATING WAKING AND SLEEPING IN THE DONKEY The clinical impact of stent edge dissection, tissue protrusion, and incomplete stent apposition (ISA) after stent implantation, detectable only on optical coherence tomography (OCT), is still unknown because the natural course has not been investigated. Sexual dysfunction induced by antipsychotic drug treatment is under investigated and under reported.

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We summarize a Cochrane systematic review that was conducted to assess the effects of low-molecular-weight heparins (LMWH) for managing vasoocclusive crises (VOC) in people with sickle cell disease. The management of cystic lesions is heavily dependent on the type of cyst, the neoplastic potential, and the risk of surgery. Since ceftriaxone was first reviewed in the Journal, further studies have confirmed its broad antibacterial spectrum in vitro and extended its clinical documentation in comparative studies with other widely used drugs in infections of the urinary and lower respiratory tract, meningitis in infants and children, uncomplicated gonorrhoea, perioperative prophylaxis in patients undergoing surgery, and in several other types of infection. Simulation results show that the recall capability obtained by using the proposed method is indeed larger than that obtained by using the conventional method.

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This latter relationship is congruent with a growing set of morphological and molecular analyses placing turtles within crown Diapsida and recognizing them as secondarily anapsid (lacking a skull fenestration). Our study emphasizes the need for adequate statistical methods and accurate study design when evaluating the contribution of genetic variants to the course of chronic liver diseases.

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A survey of the dental condition of geriatric patients on admission to hospital. Efficacy of atorvastatin on hippocampal neuronal damage caused by chronic intermittent hypoxia: Involving TLR4 and its downstream signaling pathway. After annealing at 300 degrees C for 1 h in the air, the coated specimens were evaluated by dynamic cyclic polarization tests, immersion tests, tensile tests, surface morphology observations, XRD analyses and cells culture. A cardiovascular burden index was also computed by totalling the number of cardiovascular risk factors and diseases.

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Ghrelin stimulates myogenic differentiation in a mouse muscle satellite cell line and in primary cultures of bovine myoblasts. To assess the feasibility of a study design that may determine whether subcutaneous administration of the interleukin-2 receptor antibody daclizumab can safely reduce the dependence on standard systemic corticosteroids or other immunosuppressive regimens in patients with sight-threatening, noninfectious intermediate uveitis, posterior uveitis, or panuveitis.

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EFFECT OF ADRENOCORTICOTROPIN ON THE DEVELOPMENT OF EXPERIMENTAL ARTERIOSCLEROSIS Intrafraction motion may compromise the target dose in stereotactic body radiation therapy (SBRT) of tumors in the liver. The histopathological picture and a heavy family history support the rare diagnosis of polycystic kidney disease of adult type in a new-born child. Knowledge of proper blood sampling techniques is essential for care and management of bats.

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Scanning electron microscopy: arterial endothelial integrity after fixation at physiological pressure. SFT has been described in many extrapleural sites, including the head and neck. We also found that the cysteine protease activity in the hemolymph of fp25K-mutated BmNPV-infected B. The neuraminidase inhibitors (NAIs) oseltamivir, zanamivir, laninamivir and peramivir are available in Japan.

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Twenty weeks pregnant woman was admitted with hemoptysis and dyspnea. The symptoms were managed by the use of an occlusal appliance worn at night and occasionally during the day, associated with increased awareness of parafunction during the day to reduce muscle pain and fatigue. ZnCl2 exposure reduced AChE activity and caused a mild pro-oxidative effect, since lipid peroxidation was increased in the hippocampus. International efforts in health care reform: systemic treatment funding model reform in Ontario. Sonic and ultrasonic scalers are mainly used during initial therapy and their use is often limited to the supragingival area.

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Several databases were searched using keywords relating to higher education students, mental health, and eHealth interventions. To identify the predictors of attempts to stop smoking and the predictors of quit attempt success in adult general population samples. Advanced practice nurses within acute care settings are responsible for providing healthcare to a rapidly expanding population of elderly patients. Subcellular fractionation of polyprenyl diphosphate synthase activities responsible for the syntheses of polyprenols and dolichols in spinach leaves.

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Lateralization of motor cortex excitability in stroke patients during action observation: a TMS study. Cardiac asystole after repeated administration of succinylcholine. Create a generous craniectomy in the bone flap to avoid any graft compression. This alteration was specific in the choroid plexus, since no significant difference in the binding of 125I-ANP was observed in the olfactory bulb.

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Extended scale-invariant pattern recognition with white-light illumination. This result is of practical importance in the development of immunoassays for 2-nitroimidazoles as hypoxia markers in normal and tumor tissue. ACQUIRED HEMORRHAGIC DIATHESIS CAUSED BY DEFECT OF FACTORS II, VII AND X ExoU is a potent effector protein that causes rapid host cell death upon injection by the type III secretion system of Pseudomonas aeruginosa. We conducted a retrospective analysis of 884 patients diagnosed with colorectal adenocarcinoma in the year 2002 and documented in a regional tumor registry in Southern Germany.

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It is shown that centrifugation always removes considerable amounts of both lecithin and sphingomyelin from the supernatant towards the end of pregnancy, but very little at the beginning of the last trimester. Detection of underlying tumor in patients with unknown-origin acute ICH may be difficult because acute hematoma may mask enhancement of tumor on postcontrast CT. Main peaks have good correlation between Trichosanthis Fructus and its processed products.

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These results indicate that CTLA-4 signaling is not the crucial factor in preventing sensitization to food allergens, but plays a pivotal role in regulating the intensity of a food allergic sensitization response. Data on triplets and quadruplets are too scant to be of statistical relevance. However, recent studies have demonstrated that these organisms can be surprisingly complex and dynamic. The presentation is similar to koro except that the tongue is involved instead of the penis.

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Integration of hepatitis B virus DNA into the myeloid/lymphoid or mixed-lineage leukemia (MLL4) gene and rearrangements of MLL4 in human hepatocellular carcinoma. Potentially prothrombotic flow features were found to occur periodically in the region of the upstream bearing.

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Wound healing was impaired by a single subcutaneous injection of 6 mg of methylprednisolone acetate (Depo-Medrol). Cytotoxic and antioxidant activities of alkylated benzoquinones from Maesa lanceolata. A two-strain epidemiological model was employed to simulate the transmission dynamics of dengue and to identify the relevant data gaps in empirical observations. By use of quasi-point-source optical excitation, we show how, from a series of images that form a movie of the travelling waves, the dispersion relation of the acoustic modes, their corresponding mode patterns and the position and widths of phonon stop bands can be obtained by temporal and spatio-temporal Fourier analysis. Data were analysed from a previously published descriptive qualitative study that explored perspectives of adults with hearing impairment on hearing help-seeking and rehabilitation.

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The present study re-examines this relationship, while controlling these factors. Spurious associations of alleles with disease phenotypes may be obtained or true associations overlooked when allele frequencies differ notably among subpopulations that are not represented equally among cases and controls. Trisomy for the proximal segment of the long arm of chromosome 13: a new entity?

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Silymarin is an herbal extract with antioxidant properties that can reduce oxidative stress-mediated injuries in murine models of liver, heart, and kidney diseases. High gelsolin expression and restoration of alpha-actin expression may be associated with the acquirement of flat morphology and ordered cell growth pattern, ranitidine 75 mg posologie augmentin which imply loss of tumorigenicity of R1 cells. We report on 2 brothers from a consanguineous family from a small city of southeast Turkey. With the approval of bortezomib (Velcade, PS-341), the proteosome, a master protein regulator, has been validated as an anticancer target.

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To our knowledge, this is the first report of complete response by the administration of carboplatin for non-Hodgkin lymphoma. We report a newborn infant presenting with an intra-abdominal cystic lymphangioma, in which necrosis and infection led to an unusual combination of solid doxepin 25 mg coupon and liquid areas observed by ultrasonography.

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Estimation of right ventricular mass by two-dimensional echocardiography. A purposive sampling strategy was antibiotico suprax 400 mg employed to incorporate maximum participant variation. Effects of isoflurane preconditioning in the delayed phase on myocardial tumor necrosis factor alpha levels and caspase-3 protein expression in a rabbit model of ischemia-reperfusion injury.

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AUDIOLOGIC AND OTOSCOPIC FINDINGS FOLLOWING OTITIS MEDIA IN CHILDHOOD. When compared with clear lenses from control animals of approximately the same age, the MIP26K component from Emory mouse lenses demonstrated no quantitative changes in the binding of anti-MIP26K256-263 and anti-MIP26Kwhole sera. In the present series, resection in hope of cure was viraday dosage carried out in 25 of 32 malignant tumors resulting in eight five-year survivals. Since the risk of cardiovascular and endocrinological disease is clearly elevated, proper care during adulthood is emphasized. The pp results differ, to a varying degree, from most quantum chromodynamics-inspired phenomenological models and provide the input needed to fine tune their parameters.

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Susceptibility of xeroderma pigmentosum cells to chromosome breakage by adenovirus type 12. Preventing severe AECOPD and their sequelae is a critical component in treating our patients with COPD. Synthesis of biotinylated probes of artemisinin for action of aspirin and clopidogrel vs aspirin affinity labeling.

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Comparing the PET imaging data before and after the pantoprazole 40 mg dr eckman GBP treatment, the spared nerve injury-induced increases of glucose metabolism in the thalamus and cerebellar vermis were reversed, and a significant decrease occurred in glucose metabolism in the medial prefrontal cortex (mPFC), including the anterior cingulate cortex. Observational studies, prospective, retrospective and randomized controlled studies were included. Immunoproteomic approach based on the combination of two-dimensional gel electrophoresis, immunoblotting, and mass spectrometry was applied.

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