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Toplep (Topiramate)

Toplep can be in combination with other drugs to treat partial-onset seizures, primary generalized tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome (a severe form of childhood epilepsy). Toplep has both its approved and off-label uses. In the United States, the drug is officially approved by the U.S. Food and Drug Administration (FDA)

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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In conclusion, Z-analysis was suitable both to determine the concentration of endogenous agonists and to determine true EC(50) values. nov., isolated from anaerobic granules in an upflow anaerobic sludge blanket reactor.

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Anion concentrations at which the partitioning behaviour for nucleic acids inverted (inversion point) were identified. An observation period is recommended for infants with this clinical course to allow for the opportunity of spontaneous reattachment. This study formed part of the requirements in obtaining a doctorate in veterinary medicine.

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Practice-based learning for improvement: the pursuit of clinical excellence. Differences in matching persistence behavior during block design performance between older normal and brain-damaged persons: a process analysis. A half-day conference was based upon core competencies for health professionals and involved 277 first-year health sciences, nursing, pharmacy, physical therapy, and speech language pathology and audiology students.

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The present work shows the strength of first principles assignment of lignin model bands. Three-dimensional devices, including a symmetric three-waveguide directional coupler and a three-dimensional microring resonator, are fabricated and tested.

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Myristylation of pp60c-src is not required for complex formation with polyomavirus middle-T antigen. Effect of sialoadenectomy on ethanol-induced gastric mucosal damage in the rat: role of neutrophils. It is imperative to perform a necropsy on any birds that die--whether a pet, aviary, or display bird, and despite the fact that other diseases may be present--because viruses can occur concurrently, especially when immunosuppression is present. In this study a new theory for the optimality of the branching angle is proposed, which is based on the optimization between dual competing performances, the maximum space-filling capability at the expense of minimum energy loss. Equal aversion levels for pure tones and one third-octave bands of noise.

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Chromatin-IgG complexes appear as electron dense structures (EDS) in glomerular basement membranes in lupus nephritis. Acetaldehyde significantly decreased TER, but inhibition of alcohol dehydrogenase or application of a superoxide dismutase mimetic failed to prevent alcohol-induced decreases in TER. The patient tolerated the chemotherapy well, developing grade 1 anemia and grade 2 neutropenia plus elevation of total bilirubin.

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Effects of dopamine- and serotonin-related compounds on methamphetamine-induced self-injurious behavior in mice. Our data suggest that the NAC in the present experiment decreased the ACh-induced contractility on rat-isolated ileum. Bupropion SR vs placebo for smoking cessation in health care professionals. We have combined classical subcellular fractionation with large-scale quantitative mass spectrometry to identify proteins that enrich specifically with peroxisomes of Saccharomyces cerevisiae.

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Ultrastructural study of the kidney in the coelacanth Latimeria chalumnae (Rhipidistia: Coelacanthini). Subsequent multivariate analysis was conducted on matched samples to examine the marginal effect of asthma on direct and indirect costs. It must be noted that in addition to being treated with anti-leukotriene therapy, all of these subjects continued to receive routine nasal steroid treatment. This paper presents a study on the effect of sodium salt of pyrophosphate (Na-PPi) in different concentrations (1-10 mMol/l) on the in vitro collagen fibril formation.

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ICU patients have multiple risk factors to develop hypophosphatemia and severe hypophosphatemia is a predictor of a poor prognosis. Thus, we evaluate the concentrations of circulating endothelial progenitor cells (EPCs) and stem cell modulation factors such as vascular endothelial growth factor (VEGF), erythropoietin (Epo), and substance p (SP) in the peripheral blood of diabetic retinopathy patients. Reactive Oxygen Species (ROS) are produced during normal cellular function. Proceedings of the 15th International Conference of the Pacific Basin Consortium for Environment and Health, September 24-27, Honolulu, Hawaii. Field evaluation of test-and-removal and vaccination as control measures for pseudorabies in Missouri swine.

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We conclude that pyrithione inhibits membrane transport via a direct or indirect effect on the primary proton pump which energizes transport and that the site of action of pyrithione is likely to be intra- rather than extracellular. The O(2)/H(2)/CO(2) reaction in darkness is less sensitive to ultraviolet than any of the above reactions. In 1981, during the worldwide canine parvovirus (PV) epizootic, canine transmissible venereal sarcomas growing in Beagles in a colony regressed earlier than expected after the dogs became infected with PV. Thirty-three patients, 6-18years of age, taking antiepileptic drugs and with a last seizure 1-60months prior were assigned to a maximum daily dose of 18, 36, or 54mg of OROS-MPH in a double-blind placebo-controlled crossover trial.

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Long-term dietary supplementation with L-NAC prevented oxidative damage in the hippocampus of aged rats. thermophilus were not able to release a significant level of free proline from the beta-casein hydrolysate, which was consistent with the identification of numerous dipeptides containing proline. Clinical, biological (amylasemia and amylasuria) and radiological (arteriography) signs of pancreatic disease are noticed as well as important radiological lesions of the limbs.

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Vaccination is recommended, however, to reduce the incidence of respiratory disease, abortion, and neonatal death on the farm. This review is confined to the historical background and development of the 2 principal methods of chorionic villus sampling. Thyroid hormone receptor beta-deficient mice show complete loss of the normal cholesterol 7alpha-hydroxylase (CYP7A) response to thyroid hormone but display enhanced resistance to dietary cholesterol. The results of these trials suggest that lower LDL-C levels confer a more favorable cardiovascular outcome in high-risk individuals.

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Anesthesia considerations in a patient with mcArdle disease: a case report. Terminal fragments were identified by exonuclease treatments, and linkage of fragments was deduced by a combination of single- and double-digest experiments and cross-blot hybridizations.

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The degradation of SWCNTs was catalyzed by myeloperoxidase (MPO) present in purified NETs and the reaction was facilitated by the addition of H2O2 and NaBr. Thus, BCL9 may serve to modulate and diversify the transcriptional responses to Wnt signaling in a cell-type-specific manner. Dielectrophoresis-Mediated Electrodeformation as a Means of Determining Individual Platelet Stiffness. The DIR sequence may be useful for delineating synovium without using contrast materials. The 2005 UK National Institute for Health and Clinical Excellence Improving Outcomes Guidance encompasses caring for young people with cancer in an age-appropriate model of care developing regional principal treatment centres for this purpose.

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This study aims to characterize the virological and biochemical response and to determine factors that may influence the development of resistance to adefovir. Cell lines from uveal melanoma tumors are an essential tool for these types of analyses.

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2-Amino-5-oxo-4-phenyl-5,6,7,8-tetra-hydro-4H-chromene-3-carbonitrile. We studied the improvements of Q(max,free), OG, Vmean, nocturia, and diuria after TURP and the improvements of SI, QoL, SPI, and BII. The efficacy and safety of the reducing dose HAA regimen as induction chemotherapy in previously untreated elderly patients aged 60-69 years with acute myeloid leukemia Influence of thyroid hormones on 3,4-methylenedioxymethamphetamine-induced thermogenesis and reinforcing strength in monkeys. This result was interpreted as a directed interaction between the anterior cingulate cortex and the secondary somatosensory cortex and the insula, structures that are significantly involved in the constitution of pain.

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Surface morphology (zeta potential, AFM) and surface chemistry (FTIR) confirmed conjugation of Lf on SLN surface. The element which bears some resemblance to a prism with a small radius at its apex expands the laser beam in one direction only. A gradient echo sequence which allows short repetition times was synchronized with the ECG. Permeability control in animal cells by polyenes: a possibility.

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A multi-stage control process is considered whereby the total pumping time is divided into short sampling intervals. Endoscopic resection of colorectal lesions: The narrowing divide between East and West. Multiple binding with identical linkage: a mechanism that explains the effect of lipoprotein(a) on fibrinolysis. Objects Mediate Goal Integration in Ventrolateral Prefrontal Cortex during Action Observation. We conducted a quasi-experimental study, comparing surveys at baseline and 6 months, among personnel in 10 clinics who received UBT training to personnel in 5 control clinics.

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Finally, the optimized signal processing was applied to ex vivo prostate cancer detection. This switch is extremely attractive for cascaded switching arrays such as those found in multistage interconnect networks. Dissociated perturbations of the facio-bucco-pharyngeal motricity with aphemia in a deep partial sylvian malacia

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In contrast, during the psychophysical plateau, both the intensity and volume of thalamic and cortical activations in the right medial thalamus, right posterior insula, and left secondary (S2) somatosensory cortex continued to increase with stimulus duration but not with perceived stimulus intensity. However, the biomolecular pathways and therapeutic targets specific to MB-derived CSCs remain unresolved. Antithromboplastin: the degeneration of intrinsic thromboplastin in normal serum.

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In a column system designed to incorporate aquifer flow, repeated addition of PR1 resulted in a buildup of bacterivore populations and reduced half-life of the bacterium. Although ILs are relatively safe in the atmospheric environment, they may be toxic in other environments. Two new amphibian genes have been isolated and characterized from frog melanotropes, and the level of expression of these genes is related to the secretory status of the cells.

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Proceedings: Studies on the mechanism of entry of androgens into canine prostate. Based on morphological studies reported by others, bioactive luteotropic signals identified in this study were detectable in the maternal circulation at about the time of trophoblast lacunae coalescing with maternal uterine blood vessels. Decision Support Systems and Line Performance: Case of Gold Coast University Hospital.

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A polymerase chain reaction (PCR)-based diagnostic assay was developed that rapidly and reliably differentiates the sibling species of the Anopheles claviger complex, An. FhFtn-1 contains a conserved motif of the ferroxidase center typical of vertebrate ferritins. Sweet and low: two sugar-based supergelators can congeal oils to produce highly transparent gels with glass-like refractive indices showing low UV transmittance and high visible transmittance and remarkable self-healing properties. A careful assessment of these risk factors may be important for future success in preventing PICC-related infections. Support for such a reaction has been found through kraft cooks in the presence of an added phenol, 2,6-xylenol, as well as through NMR analysis of kraft lignin.

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Exploring NUE in crops and in Arabidopsis ideotypes to improve yield and seed quality. Compared with established healthcare interventions, such as haemodialysis, renal transplantation can be considered a cost-effective therapy for patients with end-stage renal disease, even if patients are non-adherent after transplantation. The auxilin-like phosphoprotein Swa2p is required for clathrin function in yeast. Our study demonstrated no differences in total cholesterol and LDL cholesterol in infants receiving an infant formula with GOS/lcFOS from infants receiving a control infant formula. The anaesthetics tested were ketamine (0.1-2 mM), pentobarbitone (0.1-5 mM), urethane (5-200 mM), halothane (0.5-5 mM), ether (10-200 mM), alphaxalone (0.001-0.05 mM), diisopropylphenol (0.05-0.5 mM) and lignocaine (0.01-0.5 mM).

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The mechanism of autoantibody production in IFN-gamma transgenics may be relevant to human lupus and is consistent with a central role for cutaneous T cells in the pathogenesis of systemic lupus erythematosus in man. This lifestyle potentially facilitates the rapid spread of pathogens between individuals. To determine whether glatiramer acetate therapy normalizes dysregulated B-cell proliferation and cytokine production in patients with MS. This approach should be widely applicable to the study of radical processes in biological and chemical systems.

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Helicobacter pylori infection in patients with chronic hives and asthma A semitubular plate is placed over a guide wire parallel to the joint line, 1.5 cm distal to it, and is gently hammered into the tibial head with just the last hole seen outside. The patients underwent odontological clinical examination and answered a questionnaire with questions regarding dental health, medical and psychological health, and treatments undertaken from baseline to follow-up. Oxamniquine (3.6 X 10(-5)-5.5 X 10(-4) M) depressed or abolished electrically-evoked contractions of the isolated chick esophagus and isolated vas deferens muscle preparations. Effect of vitamin A restriction on carcass characteristics and immune status of beef steers.

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Silica induces nuclear factor-kappa B activation through tyrosine phosphorylation of I kappa B-alpha in RAW264.7 macrophages. Membrane type 1 (MT1)-matrix metalloproteinase (MMP) is a major mediator of collagen degradation in the pericellular space in both physiological and pathological conditions. Pretreatment with Rg1 significantly attenuated t-BHP-induced senescence in WI-38 cells. Direct observation of X-ray induced atomic motion using scanning tunneling microscope combined with synchrotron radiation.

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Hepatic splenosis refers to heterotopic auto-transplantation and implantation of splenic tissue resulting from the spillage of cells from the spleen after splenic trauma or splenectomy. USE IN PEDIATRICS OF THE THYROID FUNCTION TEST WITH I-131 LABELED TRIIODOTHYRONINE

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Change in the phase structure of systole of the left ventricle in donors after the first blood collection The authors linked patients to HA data and retrieved all claims in the 2 yr before surgery to determine the presence of any diagnostic codes, diagnostic procedures, or therapeutic interventions consistent with OSA. Contrast to sMC, LAD2 MC respond to SP with stronger histamine release and robust TNF-alpha production in an only partially neurokinin-1R mediated manner, while histamine release of sMC is chiefly mediated by this receptor.

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A study of the adjustment of 500 persons over sixteen years of age with disabilities resulting from poliomyelitis. The results show that the Trendelenburg position is vastly superior to the Valsalva manoeuvre in identifying bleeding vessels at haemostasis. For the auditory stimuli, attention was associated with a decrease in N1 latency as well as a robust P3 for the deviant tone. Identification of the regulatory subunit of a cAMP-dependent protein kinase in Dictyostelium discoideum. DNA containing the plasmid origin of bacteriophage P1 is replicated in vitro by a protein fraction prepared from uninfected Escherichia coli supplemented with purified P1 RepA protein.

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Telescoping Teflon catheters were used in one patient to dilate the tract sufficiently to remove the stone with the Dormia type wire basket. Contribution of P1-(A2b subtype) and P2-purinoceptors to the control of vascular tone in the rat isolated mesenteric arterial bed. The authors used competing risk survival analysis to formally compare associations of smoking-related variables on risk of death as a result of coronary heart disease (CHD), cerebrovascular diseases, lung cancer, other respiratory diseases, other smoking-caused cancers and other causes. Defaunation resulted in higher bacterial growth efficiency, significantly in one sheep, but the decrease after refaunation was statistically significant for both sheep. However, research on species distribution often averages environmental covariates across large geographic areas, missing variability in population-environment interactions within geographically distinct regions.

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Such studies are frequently carried out on only a few structures or else require a labor-intensive process. Retrospective cohort study of HIV-infected women delivered before (Pre-HAART) and after (Post-HAART) the introduction of HAART and scheduled cesarean delivery. This improvement resulted in more accurate information on the binding mode between proteins and ligands than in the case of conventional CoMFA. Inspired by the philosophy of the structural similarity index, we propose a C2G structural similarity (C2G-SSIM) index, which evaluates the luminance, contrast, and structure similarities between the reference color image and the C2G converted image.

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This process again turns the pseudostratified epithelium into primatic, cubic and flat epithelium. A review of irradiated fuel particle releases from the Windscale Piles, 1950-1957.

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Thymidylate synthase (TS) has been targeted in cancer therapy for many years. Certain problems of improvement of clinical training of medical students in the RSFSR Increased anti-core glycolipid antibody binding was visualized by immunoelectron microscopy after incubation of Escherichia coli K1:O7 cells with a bacteriolytic antibiotic and compared with binding in control cells. To illustrate the endovascular technique for treating tandem arterial aneurysms in the distal carotid artery.

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Increase in vasopressin concentration and cardiodepressant activity in the blood dialysates from the sella turcica during acute hypoxia. The Good Behavior Game (GBG) has been demonstrated to reduce disruptive student behavior during implementation. To perform such flights, sensor information generated by each UAV should be shared via communications. They are indispensable in progenitor cell fate determination, and various Sox family members are involved in managing the critical balance between stem cells and differentiating cells.

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typhimurium, the synonymous substitution rates can be estimated. Laser trabeculoplasty is a common treatment for open-angle glaucoma. A injecting baclofen pill id large proportion of clinical islet transplant recipients fail to initially achieve or sustain meaningful independence from exogenous insulin use. In most patients, it is associated with other congenital defects including situs inversus, malrotation, and biliary atresia or occurs as part of the heterotaxia syndrome or polysplenia syndrome.

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Ninety-one patients selected clavamox for dogs side effects respiratory one of two treatments or no intervention before oral surgery (control group). Engraftment syndrome in autologous bone marrow and peripheral stem cell transplantation.

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Correlation between apoptotic endothelial microparticles and serum interleukin-6 and C-reactive protein in healthy men. This measured frequency dependence of the THz-emission is found to be consistent with the semi-classical transient electron current model, similar to the Brunel mechanism of harmonic generation. These Indices show throughout the observation time persisting low atazanavir sulfate tablets kidney values which reflect the optimal uteroplacental circulation in a system with low downstream impedance.

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The purpose of the current study was to determine if providing instruction and products for flavor enhancement of foods to elderly cancer patients in addition to nutritional information would improve their nutritional status, and, by extension, functional and immune status as well as quality of life. Principles of SARS and avian influenza infections transmission as zoonoses are described as well as mechanisms of transmission impeding their ability to infect humans. Many graduate orthodontic programs now are teaching this technique to their residents. Parathormone and calcitonin were measured in a mysoline alcohol proportion of the children.

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Although incubation with either forskolin or (Bu)2cAMP alone stimulated estrogen production from granulosa cells, cotreatment with SOD significantly attenuated estrogen levels, indicating that SOD can inhibit aromatase activity at one or more post-FSH receptor sites. This gene, which we have named nautilus (nau), encodes basic and helix-loop-helix domains that display ribavirin mechanism of resistance antibiotics striking sequence similarity to those of the vertebrate myogenic regulatory gene family. Motile zoospores of Batrachochytrium dendrobatidis move away from antifungal metabolites produced by amphibian skin bacteria.

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The objective of this study is to provide a descriptive epidemiology of the pattern of STDs among clinic attendees at a Special Treatment Clinic (STC) of the University College Hospital (UCH), Ibadan. In women, peripheral feedback from consciously detected genital arousal seems globaxol forte to be a relatively unimportant determinant of subjective sexual arousal. THE TREATMENT OF MALUNITED FRACTURES OF THE NOSE WITH LATERAL DEVIATION.

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