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The children who underwent gastrostomy were followed up for symptoms of gastroesophageal reflux and the need for subsequent fundoplication was studied. In conclusion, our results reveal that miR-26b is downregulated in EOC, and directly targets KPNA2. We retrospectively studied patients with oral cancerous lesions of the anterior floor of the mouth reconstructed by nasolabial flap between 1997 and 2002. A prospective study conducted in Department of Medicine, Adichunchingiri Institute Of medical Sciences and Research Centre, Karnataka, over period of 1 year. Pseudoleukemia during recovery from methotrexate toxicity in psoriasis.

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Developmental aspects of thought disturbance in schizophrenic children: a Rorschach study. We report the identification of a new locus on chromosome 6q12-16 in a French family with 9 individuals affected by the pure form of autosomal dominant DCM. Karyotypic instability and viral integration in polyoma virus-induced mouse salivary gland tumors. An investigation into the role of hydroxyl radical in xanthine oxidase-dependent lipid peroxidation.

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Ultraviolet (UV) irradiation of type I poliovirus resulted in a modified (M) particle that had lost infectivity, lacked ability to adsorb to HeLa cells, lacked VP4, and reduced in S value. Most research to date has involved experimentally infected plants and animals or artificially inoculated foods. Flumazenil, 0.1 microM, had no effect after 10 days, and a 10 microM concentration had a similar effect as the 1 microM concentration. Time related aspects of arterial blood pressure, plasma volume, and electrolyte homeostasis in man.

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Markers of low-grade chronic inflammation, such as C-reactive protein (CRP) and soluble cell adhesion molecules (sCAMs), have been associated with coronary artery disease (CAD). Molecular signatures have been included to characterize different stages of the disease, and thereby the objective is to prevent unnecessary biopsies. Both degenerating pre- and postsynaptic elements appeared to be engulfed by glial processes. Because there were differences in the de novo biosynthesis capacity of purine nucleotides between DH5alpha and DA19, supplementation of adenine had completely different effect on metabolic fluxes in two strains. Hexamethonium chloride with reserpine in the treatment of severe essential hypertension.

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No statistically significant differences in quality of life were noted in any of the groups. Instead of type A particles, mature and immature type C murine virus-like particles could be observed budding from the plasma membrane to extracellular space.

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Chronic kidney disease and sexual dysfunction are common entities in clinical practice in haemodialysis (HD) units. In order to circumvent the early embryonic lethality of Gata4-null embryos and to investigate the role of myocardial Gata4 expression in cardiac development, we used Cre/loxP technology to conditionally delete Gata4 in the myocardium of mice at an early and a late time point in cardiac morphogenesis. Actual adherence was determined independently by review of medical records. Data on developmental ecology of blood-sucking mosquitoes (Diptera, Culicidae). Cross-amplification of nonspecific microsatellites markers: a useful tool to study endangered/vulnerable species of southern Andes deer.

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We propose to use the ARS ratio for two wavelengths (in our case, 632.8 and 441.6 nm) to determine the topographical properties of scattering and to study crystal surface defects. hCG-stimulated testosterone secretion by Leydig cells incubated at low density was also increased by addition of Leydig cell-conditioned medium.

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Effects of alloxan diabetes on hypothalamic hyperphagia and obesity. We postulate that the accumulation of a neurotoxic metabolite may be responsible for the disease phenotype observed. A qualitative multiple case study was conducted, where the cases are COPD patients.

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Tamoxifen but not 4-hydroxytamoxifen initiates apoptosis in p53(-) normal human mammary epithelial cells by inducing mitochondrial depolarization. To defend cells against viruses, the MAVS (mitochondrial antiviral signaling) adaptor protein initiates an antiviral signaling cascade from mitochondrial membranes. gammaD-crystallin protein structure was predicted by Swiss-Model software using bovine gammaD-crystallin as a template and Prospect software using human betab2-crystallin as a template. To what degree is it really the responsibility of the surgeon to determine and define the responsibility of the anesthetist in operative surgery? It concerned extremity injuries in soldiers treated at Togo Level 2 Hospital.

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More sensitive results, with statistical significance, were achieved using 1.5 g of feces (which corresponds to 36 Kato-Katz slides) than by using the Kato-Katz method. Discovery of lung cancer pathways using reverse phase protein microarray and prior-knowledge based Bayesian networks.

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These findings are consistent with a growing literature on eating disorders among ethnic minorities, which suggests that there may be fewer differences and more similarities among ethnic groups than previously thought. On the other hand, the concentration of sulfamethoxazole was lower in fetal tissues than in fetal fluids when relative ratios to trimethoprim were compared. They completed a battery of neuropsychological tests and a comprehensive interview assessing organic status as well as measures of the potentially confounding factors of current levels of depression and anxiety. Mifamurtide: a review of its use in the treatment of osteosarcoma.

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Paralytic shellfish poisoning in the north Pacific: two historical accounts and implications for today. The aim of this study was to assess the performance in terms of red cell damage of two peristaltic volumetric infusion pumps - the Alaris IVAC 572 (San Diego, CA, USA) and Arcomed Volumed VP7000 (Regensdorf, Switzerland). Collaborative recall and collective memory: what happens when we remember together? To examine coagulation factors and liver function test abnormalities in patients after total cavopulmonary connection (TCPC).

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It is important to understand these environmental influences and how they affect social participation. To study how migrating cells adapt to their changing environment and control their pathway, we have analysed this stereotyped migration in wild-type and mutant backgrounds.

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Gene expression studies were conducted using RT-PCR assays for nine cancer related genes. Development of an acute and highly pathogenic nonhuman primate model of Nipah virus infection. As NFMAs often compress the optic chiasm, these complaints might be related to dysfunction of the adjacent suprachiasmatic nucleus (SCN). Nine concentrations of cefotaxime in lumbar and ventricular CSF out of 19 in a group of seven neurosurgical patients with mild to moderate impairment of the blood-CSF-barrier were higher than 0.5 micrograms/ml. Considering a sample of female cardiac patients, this study shows that the construct of Vital Exhaustion is particularly present.

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The structures of the new compounds as well as a firstly literatural reported known compound (3) were assigned by spectroscopic methods including 1D/2D NMR and MS analysis techniques. INFLUENCE OF TETRACYCLINES AND OLEANDOMYCIN ON THE FLUORIMETRIC DETERMINATION OF ADRENALINE AND NORADRENALINE Cells treated with lithium (0.5-3 mM) or valproate (0.07-1.4 mM) alone produced no apoptotic morphological and biochemical changes while both mood stabilizers pretreatment reduced or prevented the apoptotic morphological changes. Major complications include pulmonary vein stenosis, stroke, and cardiac tamponade.

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Adjuvant clinical use of pPSA over traditional parameters in selecting treatment strategies for men with PCa cannot yet be definitely determined. However, these cases of substantial bone loss tend to be resolved by a hybridization of the procedures. The ages of onset of each clinical landmark were extremely variable between patients.

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The clinical manifestations are non-specific and very similar to that of patients with thromboembolic disease, resulting in delay of the correct diagnosis and proper treatment. Thus, although the components of a muscle are commonly thought to operate uniformly, a significant within-muscle temperature gradient has the potential to induce a mechanical power gradient, whereby subunits within a muscle operate with separate and distinct functional roles.

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The highest SIRs were for pancreatic (6.08) and liver (4.25) cancers. Survivin and Livin, members of the family of inhibitor of apoptosis proteins (IAPs), are specially expressed in embryonic cells and tumor cells, but are seldom expressed in normal adult cells.

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Here we present protocols for using SILAC in the following types of experiments: (i) studying inducible protein complexes, (ii) identification of Tyr kinase substrates, (iii) differential membrane proteomics and (iv) studying temporal dynamics using SILAC 5-plexing. This difference correlated with a distinct difference in cellular tropism of WM-E and F-MuLV within the epididymis of viremic males. Knockdown of CtBP1 also enhanced the sensitivity of MDR cells to chemotherapeutic drugs that are transported by P-gp and increased intracellular drug accumulation. Birth characteristics and age at menarche: results from the dietary intervention study in children (DISC).

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The present study suggests that HSPs are implicated in human periodontal disease process. Quartz crystal microbalance with dissipation (QCM-D) and optical waveguide lightmode spectroscopy monitoring were used to optimize the multistep surface modification process.

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Two patients were operated for melanoma in which surgery, at a site remote from the melanoma, suggested incomplete relapse despite the fact that previous clinical examination had indicated healthy skin. Increased oxygen or oxygen metabolites may increase oxidative stress, cell damage, intraocular pressure, and the risk of developing glaucoma. These methods often overcome many of the limitations associated with measuring atmospheric PM mass concentrations by daily filter-based methods (e.g., potential positive or negative sampling artifacts).

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Antiulcer and gastroprotective potential of Stereospermum suaveolens in Wistar Rats. Cardiac PET using (18)F-FDG under fasting conditions (fasting (18)F-FDG PET) is a promising technique for identification of cardiac sarcoidosis and assessment of disease activity. In this paper we present a recursive temporal filter with different weights (lag) for different user selected regions of interest (ROI) to assist the neurointerventionalist during an image guided catheter procedure.

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PCR amplification, sequencing, and alignment methodologies were conducted and phylogenetic tree constructed. The proven clinical efficacy of the CB(1) cannabinoid receptor antagonist rimonabant in both obesity and smoking cessation and its therapeutic potential in other disorders has given a tremendous impetus to the discovery of novel CB(1) antagonists. The recent implementation of the Diagnostic and Statistical Manual of Mental Disorders, fifth edition introduced some important changes in the conceptualization of hypersexuality and paraphilic disorders.

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Rapid bone density loss that occurs during the first year after transplant along with pre-existing bone disorder, places these patients at risk of bone fractures at three times higher than the general population. However, naming latencies were similar in the neutral condition and the unrelated condition. Concentrations of ultrafine particles are lower and of coarser (PM2.5) particles higher underground than on the surface.

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A single model compound was investigated in detail by obtaining product-ion spectra on all mono-oxygenated species in an attempt to correlate these and identify enantiomeric pairs of metabolites. Considering the increased expression level of two miRNAs in cancerous tissue compared to normal tissue as well as the area under ROC curve, miR-21 and miR-221 can be used for early detection of gastric cancer. These data demonstrate a central role for the SH2 domain in the regulation of Fes kinase activity and biological function in vivo.

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The tumour was found confined in the nasal cavity and the paranasal sinuses of a crossbred German Shepherd dog. In this study, tissue microarray and immunohistochemistry were used to investigate the expression and localization of AhR in EC tissues. To the best of our knowledge, this is one of the first study in an in vitro keratinocyte model providing evidence that cysteine and iron cooperate for keratins expression, indicative of their central role in maintaining healthy epithelia. DUST PRODUCTION IN OPEN COLD ASPHALT PLANTS AND ITS EFFECT ON SANITARY CONDITIONS IN LIVING AREAS

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Notably, AOPP-induced increase in the rate of podocyte apoptosis was partly reversed by salubrinal, an ER stress inhibitor, whereas the AOPP effect was reproduced by an inducer of ER stress, thapsigargin, suggesting that AOPPs triggered podocyte apoptosis by inducing ER stress. Median PFS with 20 and 40 mg veliparib almost doubled numerically compared with placebo, but the improvements did not reach statistical significance.

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In contrast to our hypothesis, fibrin was entirely dispensable for long-bone fracture repair, as healing fractures in fibrinogen-deficient mice were indistinguishable from those in control animals. Effect of certain antihistaminic and steroid compounds on appendiceal peritonitis. An increasing body of evidence shows that HER3 plays a critical role in EGFR- and HER2-driven tumours. Genes expressed upon insect infestation were identified in the susceptible pear cultivar Bartlett and in the resistant selection NY10355. A similar morphology was also observed following treatment with the Rho-kinase inhibitor, Y27632.

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Activity of Vitis vinifera Tendrils Extract Against Phytopathogenic Fungi. Mucinous tumours are the second most common type of epithelial ovarian tumours. It remains to be elucidated whether this phenomenon, which was particularly intense in ethynylestradiol induced cholestasis, is important in the pathogenesis and perpetuation of bile secretory failure.